2.Efficacy of Additive Trans-cuff Augmentation Sutures for Proximal Humeral Fractures Stabilized by Locking Plates in Elderly Patients.
Nam Su CHO ; Hee Seok SHIM ; Sang Hyeon LEE ; Jong Wook JEON ; Yong Girl RHEE
Clinics in Shoulder and Elbow 2015;18(2):68-74
BACKGROUND: The purpose of our study was to evaluate the functional and radiologic outcomes of additive augmentation sutures through rotator cuff for proximal humeral fractures stabilized locking plate in elderly patients. METHODS: We enrolled 74 patients over the age of 60 years who received internal fixation using locking plates for proximal humeral fractures. Of these, 50 patients had additive augmentation sutures through rotator cuff. The mean age at the time of surgery was 72.1 years (range, 60-89 years), and the mean follow-up period was 17.5 months (range, 12-62 months). The humeral neck-shaft angle and humeral head height were used as radiological markers to assess the effect of additive augmentation sutures through rotator cuff. We allocated the patients who received additive augmentation sutures into group A and those who did not into group B. RESULTS: At the final follow-up, the mean Korean Showlder Society score and Constant scores were 88.96 +/- 12.1 and 86.6 +/- 11.9, respectively, in group A and 86.21 +/- 11.8 and 85.3 +/- 11.7, respectively, in group B (p=0.368, 0.271). At the final follow-up, the mean loss in humeral neck-shaft angle from the time of immediate postoperative measurement was 1.6degrees in group A and 4.8degrees in group B, whereas the mean loss in humeral head height was 0.82 mm in group A and 0.52 mm in group B (p=0.029, 0.178). CONCLUSIONS: The surgical outcomes of internal fixation using locking plates for proximal humeral fractures were clinically and radiologically good in elderly patients over the age of 60 years without any observable complications. Further, the loss of humeral head shaft angle at the final follow-up from its initial postoperative measurement was significantly smaller in patients who received an additive augmentation suture than in those who did not. Thus, we conclude that augmentation sutures are a beneficial option for elderly patients that clinicians can consider at the time of surgical decision making.
Aged*
;
Decision Making
;
Follow-Up Studies
;
Humans
;
Humeral Head
;
Rotator Cuff
;
Shoulder Fractures*
;
Sutures*
3.A Case of Uterine Prolapse in Pregnancy.
Yun Hyeon HWANG ; Young Seok CHO ; Yong Min KIM ; In Hyun KIM ; Chung Woong KAY ; Chung No LEE
Korean Journal of Perinatology 1999;10(4):524-527
Uterine prolapse with pregnancy is rare condition. The overall incidence is 1/10000- 15000 deliveries. The complications from uterine prolapse range from minor cervical ulceration and infection to fetal death or uterine rupture. The fetal mortality was as high as 22% mainly due to prematurity, respiratory infection. The management of this condition is focused on preventing late occurrence of prolapse during pregnancy and continued reduction. We present a case of uterine prolapse in pregnancy with a brief review of the literature.
Fetal Death
;
Fetal Mortality
;
Incidence
;
Pregnancy*
;
Prolapse
;
Ulcer
;
Uterine Prolapse*
;
Uterine Rupture
4.A clinical review of the polydactyly.
Bong Su RYU ; Seung Ho KWAK ; Hwan Ik KIM ; Sam Yong LEE ; Peak Hyeon CHO
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(4):724-733
No abstract available.
Polydactyly*
5.Contractile effect of ultraviolet in isolated rat thoracic aorta.
Seung Ho KWAK ; Bong Su RYU ; Hwan Ig KIM ; Sam Yong LEE ; Paek Hyeon CHO
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(2):248-257
No abstract available.
Animals
;
Aorta, Thoracic*
;
Rats*
6.Efficacy of Endoscopic Variceal Ligation on Bleeding Esophageal Varices.
Jung Myung CHUNG ; Sang Hyuk LEE ; Sang Yong SEOL ; Sung Cheul OK ; Joon Yong JEONG ; Kil Hyeon CHO
Korean Journal of Gastrointestinal Endoscopy 1995;15(1):6-11
Endoscopic injection sclerotheraphy(EIS) was an effective method for treatment of bleeding esophageal varices. However, it might be associated with some undesirable complications. Endoscopic variceal ligation(EVL) is a recently developed method for control of active variceal bleeding and eradicating esophageal varices with similar efficacy and minimal risk of complications compare to EIS. We performed EVL in 40 patients who had recently bled from esophageal varices. Total 198 variceal ligations were performed during 64 separate EVL session. Control rate of acute bleeding was 90%(36 of 40patients) and 4 patients died after EVL because of failure of bleeding control. Rebleeding following initiation of EVL occured in 5 patients-three patients were successfully controlled by EVL, one patient was controlled but eradication was impossible and one patient died. Varices were eradicated or reduced to grade I in 31(86.1%) of 36 survivors by 1-9 ligation(mean 5.0) in l-4 EVL sessions(mean 1.6). After EVL, there were mild complications-mild substernal discomfort in 4 patients, mild dysphagia in 2 patients and fever in 2 patients. These results suggest that EVL is a safe and effective method for treatment of bleeding and eradication of esophageal varices with less complication.
Deglutition Disorders
;
Esophageal and Gastric Varices*
;
Fever
;
Hemorrhage*
;
Humans
;
Ligation*
;
Survivors
;
Varicose Veins
7.Impact of Prostate Volume on Oncological and Functional Outcomes After Radical Prostatectomy: Robot-Assisted Laparoscopic Versus Open Retropubic.
Min Soo CHOO ; Woo Suk CHOI ; Sung Yong CHO ; Ja Hyeon KU ; Hyeon Hoe KIM ; Cheol KWAK
Korean Journal of Urology 2013;54(1):15-21
PURPOSE: We compared the impact of prostate volume on oncological and functional outcomes 2 years after robot-assisted laparoscopic prostatectomy (RALP) and open radical retropubic prostatectomy (ORP). MATERIALS AND METHODS: Between 2003 and 2010, 253 consecutive patients who had undergone prostatectomy by a single surgeon were serially followed over 2 years postoperatively. RALP was performed on 77 patients and ORP on 176. The patients were divided into two subgroups according to prostate volume as measured by transrectal ultrasound: less than 40 g and 40 g or larger. Recoveries of potency and continence were checked serially by interview 1, 3, 6, 9, 12, and 24 months postoperatively. RESULTS: RALP was associated with less blood loss (ORP vs. RALP: 910 mL vs. 640 mL, p<0.001) but a longer operation time (150 minutes vs. 220 minutes, p<0.001) than was ORP. No statistically significant differences were found between the two groups for oncological outcomes, such as positive surgical margin (40% vs. 39%, p=0.911) or biochemical recurrence (12% vs. 7%, p=0.155). The overall functional outcomes showed no statistically significant differences at 2 years of follow-up (continence: 97% vs. 94%, p=0.103; potency: 51% vs. 56%, p=0.614). In the results of an inter-subgroup analysis, potency recovery was more rapid in patients who underwent RALP in a small-volume prostate than in those who underwent ORP in a small-volume prostate (3 months: 24% vs. 0%, p=0.005; 6 months: 36% vs. 10%, p=0.024). However, patients who underwent RALP in a large-volume prostate were less likely to recover continence than were patients who underwent ORP in a large-volume prostate (97% vs. 88%, p=0.025). CONCLUSIONS: Patients can be expected to recover erectile function more quickly after RALP than after ORP, especially in cases of a small prostate volume.
Erectile Dysfunction
;
Follow-Up Studies
;
Humans
;
Male
;
Prostate
;
Prostatectomy
;
Prostatic Neoplasms
;
Recurrence
;
Robotics
;
Urinary Incontinence
8.Localized Resectable Genitourinary Sarcoma in Adult Korean Patients: Experiences at a Single Center.
Sung Yong CHO ; Kyung Chul MOON ; Min Su CHEONG ; Cheol KWAK ; Hyeon Hoe KIM ; Ja Hyeon KU
Yonsei Medical Journal 2011;52(5):761-767
PURPOSE: To evaluate the clinicopathological characteristics and prognosis of localized resectable genitourinary sarcomas in adults. MATERIALS AND METHODS: Between September, 1996 and November, 2008, 18 consecutive cases of adults (12 men and 6 women; median age 48.8 years) who were treated for primary genitourinary sarcomas were identified. The following variables were analyzed: patient age, gender, body mass index, American Society of Anesthesiologists (ASA) score, primary organ, tumor histology, size, necrosis, Federation Nationale des Centres de Lutte Contre le Cancer (FNCLCC) grade, and surgical margin positivity. Recurrence-free survival and disease-specific survival were the study end-points. RESULTS: The most common presenting symptom was a palpable mass (six cases, 33.3%), the most common site was the kidney (six cases, 33.3%), and the most common histological subtype was leiomyosarcoma (eight patients, 44.4%). Complete resection with negative surgical margins was achieved in 13 patients (72.2%). The median follow-up period was 49.9 months (range 6.4 to 147.6). The recurrence-free survival rates at 1, 3, and 5 years were 81.6%, 66.5%, and 66.5%, respectively. Recurrence-free survival only associated significantly with ASA score (p=0.018). The disease-specific survival rate at 1, 3, and 5 years was 88.9%, 76.2%, and 67.7%, respectively. Disease-specific survival was associated significantly only with FNCLCC grade (p=0.042). CONCLUSION: Although genitourinary sarcomas in adults are a rare group of tumors with a poor prognosis, some patients may have a favorable prognosis. Our findings suggest that FNCLCC grade is the most important prognostic factor for these patients.
Adult
;
Aged
;
Female
;
Humans
;
Immunohistochemistry
;
Kaplan-Meier Estimate
;
Male
;
Middle Aged
;
Neoplasm Grading
;
Prognosis
;
Republic of Korea
;
Sarcoma/metabolism/pathology/*surgery
;
Urogenital Neoplasms/metabolism/pathology/*surgery
;
Young Adult
9.Effect of Nitric Oxide on the Cryopreservation of Platelets.
Jae Hyeon LEE ; Jeong Tae KIM ; Yong Gon CHO
The Korean Journal of Laboratory Medicine 2008;28(2):136-143
BACKGROUND: To determine whether nitric oxide (NO) could inhibit activation of platelets stored in a cold or frozen state, we measured platelet P-selectin expression and platelet-bound fibrinogen in platelet-rich plasma (PRP) with S-nitrosoglutathione (GSNO) (Sigma, USA) by flow cytometry. METHODS: PRP was prepared by centrifuging venous blood collected in a 3.2% sodium citrate tube from 10 healthy donors. It was aliquotted into 4 groups (no cryoprotectant, GSNO, GSNO/dimethyl sulfoxide [DMSO] [Sigma], and DMSO), and stored at room, cold and freezing temperatures for 24 hrs. We performed a flow cytometric analysis of all specimens stained with FITC-fibrinogen and PE-CD62P monoclonal antibodies (Becton Dickinson, USA). The results were compared according to the storage temperature and agonist among 4 groups. RESULTS: GSNO inhibited significantly the activation of frozen platelets, but not in the presence of DMSO. GSNO was also shown to preserve the aggregability of frozen platelets because in the presence of GSNO the delta percent change of P-selectin expression and fibrinogen binding of frozen platelets increased significantly irrelevant to DMSO. CONCLUSIONS: GSNO inhibited the activation of frozen platelets and preserved the platelet aggregability; therefore, it may be used as a protectant for platelet cryopreservation.
Adult
;
Blood Platelets/*drug effects/metabolism
;
Cryopreservation/*methods
;
Female
;
Fibrinogen/metabolism
;
Flow Cytometry
;
Free Radical Scavengers/pharmacology
;
Humans
;
Male
;
Nitric Oxide/metabolism
;
Nitric Oxide Donors/*pharmacology
;
P-Selectin/metabolism
;
Platelet Aggregation/drug effects
;
Platelet Aggregation Inhibitors/pharmacology
;
S-Nitrosoglutathione/*pharmacology
10.Influence of Isoproterenol on the Plasma Renin Activity in Rats.
Woong Kyou PARK ; Yong Bae SHIN ; In soo CHOI ; Hyeon Suk LEE ; Jung Soo KIM ; Kyung Woo CHO
Journal of the Korean Pediatric Society 1985;28(9):899-905
No abstract available.
Animals
;
Isoproterenol*
;
Plasma*
;
Rats*
;
Renin*