1.A clinical study on neonatal bacterial meningitis.
Yong Won PARK ; Jung Hwan CHOI ; Chong Ku YUN
Journal of the Korean Pediatric Society 1991;34(6):763-770
No abstract available.
Humans
;
Infant, Newborn
;
Meningitis, Bacterial*
2.A clinical analysis of incisional hernia.
Phil Soon PARK ; Yong Hwan JUNG ; Kun Pil CHOI
Journal of the Korean Surgical Society 1993;44(6):1029-1037
No abstract available.
Hernia*
3.Contractile Responses to Endothelins in Isolated Arteries from Human Uterus.
Ook Hwan CHOI ; Mi Kyung JANG ; Byung Yong RHIM
Korean Journal of Obstetrics and Gynecology 1999;42(3):582-590
OBJECTIVE: We examined the vasoconstricting poperties of endothelin (ET) on isolated arteries from pregnant as well as non-pregnant uterus. METHODS: Arteries of the uterus were obtained from both hysterectomized uterus and during pregnany hysterectomy for control group and cesarean section for pregnant group. Rings of uterine artery were suspended on muscle chambers at their optimal length for generating tension and contractile properties were examined. RESULTS: ET-1 and ET-2 induced concentration-dependent constriction of both isolated arterial strips from non-pregnant and pregnant uterus. The contraction to ET-1 and ET-2 were more enhanced in full-term pregnancy. Furthermore, in pregnant group, sarafotoxin S6c and IRL 1620, ET. agonists, induced a dose-dependent contraction, which was not shown in those from non-pregnant human. Pretreatment of human uterine arterial strips from pregnant uterus with BQ610, an ET. antagonist, for 10 min resulted in a dose-related rightward shift of ET-1 response curve with diminution of maximal response. Schild plot analysis yielded a pA value of 7.29 with a slope of 0.98. However, BQ788, an ET antagonist, did not produce any rightward shift. The contraction to lower concentration (10-8~3*10-7 M) of sarafotoxin S6c was not affected by BQ788, whereas that to higher concentration (10-s-8*10-7 M) was marked diminished. However, BQ610 did not exnt any efFect on sarafotoxin S6c-induced contraction in arterial staips from pregnant uterus. When the bath solution was replaced with Ca-free physiological salt solution (PSS) containing 1 mM EGTA for 10 min prior to adding sarafotoxin S6c, sarafotoxin S6c-induced contraction was completely abolished. Sarafotoxin S6c (10 nM)-induced contraction was prefetentially blocked by a protein kinase C antagonist, H-7, whereas it was less sensitive to a calmodulin antagonist, calmidazolium, CONCLUSION: Based on above results, we concluded that ET plays an important role in regulating uterine blood flow through the activation of ETa and ETB receptors. Furthermote, ETB receptors may predominantly contribute to the modulation of human uterine circulation in full-term pregnancy.
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
;
Arteries*
;
Baths
;
Calmodulin
;
Cesarean Section
;
Constriction
;
Egtazic Acid
;
Endothelin-2
;
Endothelins*
;
Female
;
Humans*
;
Hysterectomy
;
Pregnancy
;
Protein Kinase C
;
Receptors, Endothelin
;
Uterine Artery
;
Uterus*
4.Clinical aspects of the preoperative selective angiogrpahy in patients and periampullary tumors.
Jin Woo RYU ; Sang Yong CHOI ; Bum Hwan KOO
Journal of the Korean Surgical Society 1992;42(1):37-42
No abstract available.
Humans
5.A clinical review of fistula-in-ano.
Chung Hwan CHOI ; Joong Kyou KIM ; Yong Ki PARK ; Chang Rock CHOI
Journal of the Korean Society of Coloproctology 1993;9(3):255-260
No abstract available.
6.Detection of human CTLA-4 by using anti-peptide antibody.
Yong Hoon CHUNG ; Yang Ja CHO ; Seog Won LEEM ; Chang Hwan PARK ; Yong CHOI ; Dupont BO
Journal of the Korean Society for Microbiology 1993;28(3):229-237
No abstract available.
Humans*
7.The incidence of complications in severely obese children.
Dong Hwan LEE ; Chul LEE ; Chong Guk LEE ; Yong Seung HWANG ; Sung Ho CHA ; Yong CHOI
Journal of the Korean Pediatric Society 1991;34(4):445-453
No abstract available.
Child*
;
Fatty Liver
;
Humans
;
Hypercholesterolemia
;
Incidence*
;
Obesity
8.Doxycycline - Induced Esophageal Ulcers.
Jae Wang KIM ; Jang Yong HWANG ; Kyu Sik KWACK ; Yong Hwan CHOI ; Joon Mo CHUNG
Korean Journal of Gastrointestinal Endoscopy 1985;5(1):33-35
Esophageal ulcers induced by doxycycline is a rare complication. These patients usually complain of sudden onset of symptoms, ie acute substernal or chest pain and odynophagia without prior hietory of esophageal syraptoms. On esophagoscopic examination, there are upper or midesophageal ulcers, which heal after diseontinuation of the drug within 2 weeks. A history of ingestion of the doxycycline,with liquid jost before bedtime can be elicited. The exact eause of the xaucosal ulceration is not clear, but a direct irritant effeet on esophageal mucosa seems most likely. We report 5 cases of esophageal uleeration secondary to the ingestion of doxycydine. Esophagoscopy revealed esophageal ulcers in all patients and the patients hecame asymptomatic following stopping of tbe drugs and taking antacids.
Antacids
;
Chest Pain
;
Doxycycline*
;
Eating
;
Esophagoscopy
;
Humans
;
Mucous Membrane
;
Ulcer*
10.Mechanical ventilator care in the newborn infants.
Young Pyo CHANG ; Yong Won PARK ; Won Soon PARK ; Jung Hwan CHOI ; Chong Ku YUN
Journal of the Korean Pediatric Society 1991;34(11):1526-1533
No abstract available.
Humans
;
Infant, Newborn*
;
Respiration, Artificial
;
Survival Rate
;
Ventilators, Mechanical*