1.The toxic effects of cryoprotectants on the mouse embryo.
Chung Hoon KIM ; Shin Yong MOON ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(10):1400-1409
No abstract available.
Animals
;
Embryonic Structures*
;
Mice*
2.A rural health study through screening approaches.
Gil Soo SON ; Yong Tae YUM ; Soung Hoon CHANG
Korean Journal of Epidemiology 1991;13(2):197-203
No abstract available.
Mass Screening*
;
Rural Health*
3.Treatment of Diaphyseal Fractures of the Radius and Ulna with Dynamic Compression Plates: A Retrospective Study of 52 Fractures in 33 Patients
Chang Hoon MOON ; Chi Dong SOHN ; Yong Ju KIM
The Journal of the Korean Orthopaedic Association 1986;21(5):885-891
Reduction of displaced diaphyseal fractures of the radius and ulna in adult must be nearly anatomical for restoration of mormal function. Most of the fractures require operative management, and various methods of open reduction and internal fixation have been recommended. Because we believe that anatomical reduction followed by rigid internal fixation provides the most satisfactory results for these injuries, dynamic compression plating method is frequently used in our hos pi tal. We studied 52 diaphyseal fractures of the forearm bone in 33 patients treated at the S.R.C.H. from May 1980 to December 1985. Of the 33 patients, 20 had fractures of the radius and ulna; 6, fractures of the radius only; and 7, fractures of the ulna only. The fractures of both bones were treated with plate and screws in 19 patients. In another one, the ulna was treated with plate and screws and the radius was treated by screw fixation only. The results were as follows: l. Of the 52 fractures, 51(98.1%) were united after the initial operation within 23 weeks. 2. The average time for radiological union of the fracture, excluding those complicated by infection or non-union, was 11.1 weeks for 24 radii and 10.9 weeks for 25 ulnae. 3. Only one patient(3.0%) was complicated by infection and only one(1.9%) non-union of radius occurred. 4. The functional results were excellent or satisfactory in 25 patients(83.3%). 5. We have found that in adults the auto compression plating is a successful method for the diaphyseal fractures of the forearm.
Adult
;
Diaphyses
;
Forearm
;
Humans
;
Methods
;
Radius
;
Retrospective Studies
;
Ulna
4.Detection of human CTLA-4 by using anti-peptide antibody.
Yong Hoon CHUNG ; Yang Ja CHO ; Seog Won LEEM ; Chang Hwan PARK ; Yong CHOI ; Dupont BO
Journal of the Korean Society for Microbiology 1993;28(3):229-237
No abstract available.
Humans*
5.Multi-dimensional Changes in Auditory Verbal Hallucination during Antipsychotic Treatment of Schizophrenic Patients.
Jae Seung CHANG ; Seong Hoon JEONG ; Yong Min AHN ; Yong Sik KIM
Journal of Korean Neuropsychiatric Association 2005;44(1):65-74
OBJECTIVES: Auditory verbal hallucination (AVH) is knoun for its high prevalence and difficulty in evaluation. Authors hypothesized that it may be possible to find useful dimensions of AVH that reflect the clinical status of schizophrenic patients by assessing the multi-dimensional changes and linguistic forms' of AVH during antipsychotic treatment. METHODS: 33 schizophrenic patients with AVH were selected and periodically assessed with the 11 items of hallucinations subscale of 'The Psychotic Symptom Rating Scales (PSYRATS)'. In addition, to assess the linguistic forms observed in the AVH, the evaluations of sentence structure of AVH reported by the patients were conducted. RESULTS: PSYRATS showed the multidimensionality inherent in AVH. The changes in the quantitative dimensions did not correlate well with patients' subjective distress. However, qualitative changes in the cognitive and emotional dimensions showed more favorable correlation with clinical course of the patient. The sentence structures of AVH showed tendency to change from "sentence" to "non-sentence" type with overall improvement during treatment. CONCLUSION: Multi-dimensional approach to AVH can give us more information about the changing patterns of multi-faceted structure of AVH and clinical status of patients than one-dimensional or categorical approach.
Hallucinations*
;
Humans
;
Linguistics
;
Prevalence
;
Weights and Measures
6.Multi-dimensional Changes in Auditory Verbal Hallucination during Antipsychotic Treatment of Schizophrenic Patients.
Jae Seung CHANG ; Seong Hoon JEONG ; Yong Min AHN ; Yong Sik KIM
Journal of Korean Neuropsychiatric Association 2005;44(1):65-74
OBJECTIVES: Auditory verbal hallucination (AVH) is knoun for its high prevalence and difficulty in evaluation. Authors hypothesized that it may be possible to find useful dimensions of AVH that reflect the clinical status of schizophrenic patients by assessing the multi-dimensional changes and linguistic forms' of AVH during antipsychotic treatment. METHODS: 33 schizophrenic patients with AVH were selected and periodically assessed with the 11 items of hallucinations subscale of 'The Psychotic Symptom Rating Scales (PSYRATS)'. In addition, to assess the linguistic forms observed in the AVH, the evaluations of sentence structure of AVH reported by the patients were conducted. RESULTS: PSYRATS showed the multidimensionality inherent in AVH. The changes in the quantitative dimensions did not correlate well with patients' subjective distress. However, qualitative changes in the cognitive and emotional dimensions showed more favorable correlation with clinical course of the patient. The sentence structures of AVH showed tendency to change from "sentence" to "non-sentence" type with overall improvement during treatment. CONCLUSION: Multi-dimensional approach to AVH can give us more information about the changing patterns of multi-faceted structure of AVH and clinical status of patients than one-dimensional or categorical approach.
Hallucinations*
;
Humans
;
Linguistics
;
Prevalence
;
Weights and Measures
7.Inhibition of IL-2 dependent DTLL-2 proliferation by immune complex from patient with ovarian cancer.
Sang Deuk CHUNG ; Chang Hwan PARK ; Yong Hoon CHUNG ; Kyung Hee KIM ; Yang Ja CHO
Journal of the Korean Society for Microbiology 1993;28(4):331-327
No abstract available.
Antigen-Antibody Complex*
;
Humans
;
Interleukin-2*
;
Ovarian Neoplasms*
8.Hemichorea Associated with Hyperglycemia: A Case Showing Increased Blood Flow in the Contralateral Striatum.
Chang Min LEE ; Dae Woong YONG ; Sang Hoon HONG
Journal of the Korean Neurological Association 1999;17(5):770-773
We report a diabetic woman who developed paroxysmal hemichorea during an episode of non-ketotic hyper-glycemia. A MRI showed a high signal intensity on T1-weighted images and a low signal intensity on T2-weighted images in the contralateral putamen. SPECT on the 30th day after the onset revealed an increased blood flow in the contralateral striatum. Although these abnormalities in the left putamen are considered to be the cause of her involuntary movement, the exact pathophysiological mechanisms of these abnormalities are not yet clear and further investigations are needed.
Dyskinesias
;
Female
;
Humans
;
Hyperglycemia*
;
Magnetic Resonance Imaging
;
Putamen
;
Tomography, Emission-Computed, Single-Photon
9.Changes of Serum Inhibin Concentration in Controlled Ovarian Hyperstimulation for IVF-ET.
Shin Yong MOON ; Seok Hyun KIM ; Jae Hoon LEE ; Chang Suk SUH
Korean Journal of Obstetrics and Gynecology 1998;41(11):2795-2805
Inhibin is a glycoprotein usually produced by granulosa cell of ovary and is known as regulator of FSH secretion. Inhibin is consisted of two heterodimeric subunit of a, B . There are two distinct molecular forms of the B subunit that exist (BA and BB) and when combined with an a subunit, form inhibin A, and inhibin B, respectively. Ovarian reserve describes women's reproductive potential, which usually decreased according to chronological age. Because useful markers claimed for the prediction of ovarian response during controlled ovarian hyperstimulation for IVF-ET have not been always successful, new biomarker has been investigated. The purpose of this study was to observe the changes in serum and ovarian follicular inhibin A concentration during controlled ovarian hyperstimulation for IVF-ET program and to evaluate the clinical significance of inhibin A as a prognostic marker for assisted reproductive technology outcomes. From Jan 1996 to Dec 1996, 48 patients who underwent IVF-ET were included. In each patient, the Day 3 FSH, LH, E2q were measured in the first month of cycle before commencing GnRH agonist administration, In the stimulation period after pituitary down regulation, blood samples for inhibin A were collected at the day 3, day 7, day of hCG injection, day of oocytes aspiration, and day of embryo transfer. Ovarian follicular inhibin A was collected at the day of oocyte aspiration. Inhibin A concentration was measured using test kit for inhibin A (INHIBIN-EASIA (code 40.134.00), Belgium Medgenix). The changes in serum inhibin A, E2 concentration during IVF-ET program showed increasing pattern throughout controlled ovarian hyperstimulation periods. If the cut-off value of day 3 serum inhibin A determined to 0.28 U/ml, the sensitivity and specificity were 80.0%, 75.0% respectively in predicting the number of oocytes retrieved being more than five. If the cut-off value of peak serum E determined to 1316 pg/ml, the sensitivity and specificity were 89.0%, 100.0% respectively in predicting the number of oocytes retrieved being more than five. In conclusion, measurement of serum inhibin A concentration on the day of starting stimulation (day 3) could be used as a useful marker for predicting the ovarian response in IVF-ET program.
Belgium
;
Down-Regulation
;
Embryo Transfer
;
Female
;
Glycoproteins
;
Gonadotropin-Releasing Hormone
;
Granulosa Cells
;
Humans
;
Inhibins*
;
Oocyte Retrieval
;
Oocytes
;
Ovary
;
Reproductive Techniques, Assisted
;
Sensitivity and Specificity
;
Serum
10.The Implementation of Pattern Classifier for Karyotype Classification.
Yong Hoon CHANG ; Kwon Soon LEE ; Gye Rok JUN
Journal of Korean Society of Medical Informatics 1997;3(2):207-214
The human chromosome analysis is widely used to diagnose genetic disease and various congenital anomalies. Many researches on automated chromosome karyotype analysis has been carried out, some of which produced commercial systems. However, there still remains much room for improving the accuracy of chromosome classification. In this paper, We propose an optimal pattern classifier by neural network to improve the accuracy of chromosome classification. The proposed pattern classifier was built up of multi-step multi-layer neural network(MMANN). We reconstructed chromosome image to improve the chromosome classification accuracy and extracted three morphological features parameters such as centromeric index(C.1.), relative length ratio(R.L.), and relative area ratio(R.A.). This Parameters employed as input in neural network by preprocessing twenty human chromosome images. The experiment results show that the chromosome classification error is reduced much more than that of the other classification methods.
Chromosomes, Human
;
Classification*
;
Humans
;
Karyotype*