1.The toxic effects of cryoprotectants on the mouse embryo.
Chung Hoon KIM ; Shin Yong MOON ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(10):1400-1409
No abstract available.
Animals
;
Embryonic Structures*
;
Mice*
2.Treatment of Diaphyseal Fractures of the Radius and Ulna with Dynamic Compression Plates: A Retrospective Study of 52 Fractures in 33 Patients
Chang Hoon MOON ; Chi Dong SOHN ; Yong Ju KIM
The Journal of the Korean Orthopaedic Association 1986;21(5):885-891
Reduction of displaced diaphyseal fractures of the radius and ulna in adult must be nearly anatomical for restoration of mormal function. Most of the fractures require operative management, and various methods of open reduction and internal fixation have been recommended. Because we believe that anatomical reduction followed by rigid internal fixation provides the most satisfactory results for these injuries, dynamic compression plating method is frequently used in our hos pi tal. We studied 52 diaphyseal fractures of the forearm bone in 33 patients treated at the S.R.C.H. from May 1980 to December 1985. Of the 33 patients, 20 had fractures of the radius and ulna; 6, fractures of the radius only; and 7, fractures of the ulna only. The fractures of both bones were treated with plate and screws in 19 patients. In another one, the ulna was treated with plate and screws and the radius was treated by screw fixation only. The results were as follows: l. Of the 52 fractures, 51(98.1%) were united after the initial operation within 23 weeks. 2. The average time for radiological union of the fracture, excluding those complicated by infection or non-union, was 11.1 weeks for 24 radii and 10.9 weeks for 25 ulnae. 3. Only one patient(3.0%) was complicated by infection and only one(1.9%) non-union of radius occurred. 4. The functional results were excellent or satisfactory in 25 patients(83.3%). 5. We have found that in adults the auto compression plating is a successful method for the diaphyseal fractures of the forearm.
Adult
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Diaphyses
;
Forearm
;
Humans
;
Methods
;
Radius
;
Retrospective Studies
;
Ulna
3.A rural health study through screening approaches.
Gil Soo SON ; Yong Tae YUM ; Soung Hoon CHANG
Korean Journal of Epidemiology 1991;13(2):197-203
No abstract available.
Mass Screening*
;
Rural Health*
4.Detection of human CTLA-4 by using anti-peptide antibody.
Yong Hoon CHUNG ; Yang Ja CHO ; Seog Won LEEM ; Chang Hwan PARK ; Yong CHOI ; Dupont BO
Journal of the Korean Society for Microbiology 1993;28(3):229-237
No abstract available.
Humans*
5.Multi-dimensional Changes in Auditory Verbal Hallucination during Antipsychotic Treatment of Schizophrenic Patients.
Jae Seung CHANG ; Seong Hoon JEONG ; Yong Min AHN ; Yong Sik KIM
Journal of Korean Neuropsychiatric Association 2005;44(1):65-74
OBJECTIVES: Auditory verbal hallucination (AVH) is knoun for its high prevalence and difficulty in evaluation. Authors hypothesized that it may be possible to find useful dimensions of AVH that reflect the clinical status of schizophrenic patients by assessing the multi-dimensional changes and linguistic forms' of AVH during antipsychotic treatment. METHODS: 33 schizophrenic patients with AVH were selected and periodically assessed with the 11 items of hallucinations subscale of 'The Psychotic Symptom Rating Scales (PSYRATS)'. In addition, to assess the linguistic forms observed in the AVH, the evaluations of sentence structure of AVH reported by the patients were conducted. RESULTS: PSYRATS showed the multidimensionality inherent in AVH. The changes in the quantitative dimensions did not correlate well with patients' subjective distress. However, qualitative changes in the cognitive and emotional dimensions showed more favorable correlation with clinical course of the patient. The sentence structures of AVH showed tendency to change from "sentence" to "non-sentence" type with overall improvement during treatment. CONCLUSION: Multi-dimensional approach to AVH can give us more information about the changing patterns of multi-faceted structure of AVH and clinical status of patients than one-dimensional or categorical approach.
Hallucinations*
;
Humans
;
Linguistics
;
Prevalence
;
Weights and Measures
6.Multi-dimensional Changes in Auditory Verbal Hallucination during Antipsychotic Treatment of Schizophrenic Patients.
Jae Seung CHANG ; Seong Hoon JEONG ; Yong Min AHN ; Yong Sik KIM
Journal of Korean Neuropsychiatric Association 2005;44(1):65-74
OBJECTIVES: Auditory verbal hallucination (AVH) is knoun for its high prevalence and difficulty in evaluation. Authors hypothesized that it may be possible to find useful dimensions of AVH that reflect the clinical status of schizophrenic patients by assessing the multi-dimensional changes and linguistic forms' of AVH during antipsychotic treatment. METHODS: 33 schizophrenic patients with AVH were selected and periodically assessed with the 11 items of hallucinations subscale of 'The Psychotic Symptom Rating Scales (PSYRATS)'. In addition, to assess the linguistic forms observed in the AVH, the evaluations of sentence structure of AVH reported by the patients were conducted. RESULTS: PSYRATS showed the multidimensionality inherent in AVH. The changes in the quantitative dimensions did not correlate well with patients' subjective distress. However, qualitative changes in the cognitive and emotional dimensions showed more favorable correlation with clinical course of the patient. The sentence structures of AVH showed tendency to change from "sentence" to "non-sentence" type with overall improvement during treatment. CONCLUSION: Multi-dimensional approach to AVH can give us more information about the changing patterns of multi-faceted structure of AVH and clinical status of patients than one-dimensional or categorical approach.
Hallucinations*
;
Humans
;
Linguistics
;
Prevalence
;
Weights and Measures
7.Hemichorea Associated with Hyperglycemia: A Case Showing Increased Blood Flow in the Contralateral Striatum.
Chang Min LEE ; Dae Woong YONG ; Sang Hoon HONG
Journal of the Korean Neurological Association 1999;17(5):770-773
We report a diabetic woman who developed paroxysmal hemichorea during an episode of non-ketotic hyper-glycemia. A MRI showed a high signal intensity on T1-weighted images and a low signal intensity on T2-weighted images in the contralateral putamen. SPECT on the 30th day after the onset revealed an increased blood flow in the contralateral striatum. Although these abnormalities in the left putamen are considered to be the cause of her involuntary movement, the exact pathophysiological mechanisms of these abnormalities are not yet clear and further investigations are needed.
Dyskinesias
;
Female
;
Humans
;
Hyperglycemia*
;
Magnetic Resonance Imaging
;
Putamen
;
Tomography, Emission-Computed, Single-Photon
8.Expression of Osteopontin in Osteoclast.
Jae Suk CHANG ; Jong Hoon PARK ; Yong Gu PARK ; Jeong Hwa KIM
Journal of Korean Orthopaedic Research Society 1999;2(2):132-138
PURPOSE: This study was aimed to determine the relationship between osteopontin(OPN) and osteoclast, especially focused on whether ostecolast could produce osteopontin or not. MATERIALS AND METHODS: Osteoclasts were isolated from the giant cell tumor of proximal tibia and seeded on the 13 mm round cover slip resided in 24 multi-well plates for culture. After 2 days, osteclasts on the cover slip were fixed with cold acetone for 3 minutes and immunocytochemistry was done with rabbit osteopontin antibody. For in situ RT-PCR, osteoclasts on the cover-slips were fixed with 4% paraformaldehyde for 4 hours and were treated to pepsin. PR-PCR was done and the PCR producst were stained with anti-digoxigenin-AP. RESULTS: Osteopontins were found on the surface of the osteoclast by immunocytochemistry, and intense osteopontin mRNAs were found by in situ RT-PCR. CONCLUSION: We have identified that osteoclast could synthesize the osteopontin, and confirmed that in situ RT-PCR was a very useful method in expressing small amount of mRNA in case of mixed cell culture. Further study was needed to identify the action of the osteopontin produced by the osteoclast.
Acetone
;
Cell Culture Techniques
;
Giant Cell Tumors
;
Immunohistochemistry
;
Osteoclasts*
;
Osteopontin*
;
Pepsin A
;
Polymerase Chain Reaction
;
RNA, Messenger
;
Tibia
9.Expression of human CTL?4 extracellular domain in escherichia coli.
Chang Hwan PARK ; Seung Hyun SEO ; Yong Hoon CHUNG ; Yang Ja CHO
Korean Journal of Immunology 1993;15(2):129-137
No abstract available.
Escherichia coli*
;
Escherichia*
;
Humans*
10.Height Changes of Intervertebral Disc and Neural Foramen after Anterior Lumbar Interbody Fusion in the Lumbar Spine.
Chang Hoon JEON ; Yong Chan KIM ; Nam Su CHUNG
Journal of Korean Society of Spine Surgery 2003;10(3):226-232
STUDY DESIGN: A prospective clinical study with radiologic assessment was conducted. OBJECTIVES: To analyze the height changes of the intervertebral disc and neural foramen and width changes of the neural foramen after anterior lumbar interbody fusion and posterior fixation in the lumbar spine. SUMMARY OF LITERATURE REVIEW : Anterior lumbar interbody fusion distracts the height of the intervertebral disc and neural foramen and the width of the neural foramen. MATERIALS AND METHODS: Minimal anterior lumbar interbody fusion and posterior fixation were performed in 20 cases from January 1999 to January 2001. The measuring factors were the height of the anterior and posterior discs, and the height and width of the neural foramen, measured with a caliper in 1mm reconstructive, computed tomography, sagittal images before and 6 months after anterior lumbar interbody fusion. The factors were independently measured by three different persons. RESULTS: The height of the anterior and posterior discs was increased by mean 32.2% and 40.5%, respectively. The height of the right and left neural foramen was increased by mean 15.7% and 18.3%, respectively. The width of the superior, middle and inferior neural foramen was increased by mean 20.6%, 30.3% and 38.6%, respectively. There were significant increases in all measuring factors after minimal anterior lumbar interbody fusion. CONCLUSIONS: Minimal anterior lumbar interbody fusion significantly increased the height of the anterior and posterior intervertebral discs, and the height and width of the neural foramen, and produced neural decompression.
Decompression
;
Humans
;
Intervertebral Disc*
;
Prospective Studies
;
Spine*