We examined a male infant with transient increase in alkaline phosphatase(ALP) activity. The 25-month-old infant was admitted to a local hospital because of pneumonia of unknown etiology. Initial laboratory investigation revealed a serum ALP of 11,260U/L, which was comparable to that of bone isoenzyme on the electrophoresis pattern, There was no evidence of hepatitis, skeletal or intestinal diseases. The hyperphosphatasemia disappeared 3 months later. We report a case of transient hyperphosphatasemia diagnosed inci- dentally in the course of management of pneumonia. (J Korean Pediatr Soc 2000;43:856-860)
Alkaline Phosphatase ; Child, Preschool ; Electrophoresis ; Hepatitis ; Humans ; Infant ; Intestinal Diseases ; Male ; Pneumonia

No abstract available.
Child* ; Fatty Liver ; Humans ; Hypercholesterolemia ; Incidence* ; Obesity

Endometrial papillary serous carcinoma (EPSC) is a distinct variant of endometrial adenocarcinoma that histologically resembles ovarian serous papillary adenocarcinoma and has an aggressive clinical course. Usually, the tumor is diagnosed at the advanced stage. The tumor has well confused with metastatic ovarian tumor of identical histology. Dignosis of EPSC should be considered when the cervico-vaginal smear reveals numerous papillary clusters of tumor cells with macronucleoli and psammoma bodies. Recently, we have experienced two cases of EPSC diagnosed on cervico-vaginal smears, which revealed characteristic cytologic features including numerous papillary clusters of tumor cells with macronucleoli. The cytologic diagnoses were confirmed on histologic sections.
Adenocarcinoma ; Adenocarcinoma, Papillary ; Diagnosis ; Polycystic Kidney, Autosomal Recessive*

The authors have analyzed retrospectively a series of 102 consecutive patient with severe head injury who were admitted to the department of Neurosurgery, Dong Guk Univ. Hosp. between January, 1989, and December, 1989. All patients, after appropriate cardiopulmonary resuscitation, diagnostic measure, and, when required, surgical treatment, were managed in ICU with usual care method. The outcome has been analyzed 4 month later. The overall mortality rate was 36%. Of the survivors, 65% made good recovery or moderate disability, 22% remained severely disabled, and 14% were in a persistent vegetative state. Mortality rates at the variable GCS scores were 82% at 3-4, 25% at 5-6, and 14% at 7-8. The most reliable predictive factors were : Glasgow coma scale, motor response, pupillary reflex at admission.
Cardiopulmonary Resuscitation ; Craniocerebral Trauma* ; Glasgow Coma Scale ; Head* ; Humans ; Mortality ; Neurosurgery ; Persistent Vegetative State ; Reflex, Pupillary ; Retrospective Studies ; Survivors

No abstract available.
Zygoma*

The double eyelid operation is one of the most common cosmetic surgery performed in orientals, and there are numerous studies about surgical procedures of that. In the case of appropriate candidates, the non-incision technique makes excellent cosmetic results, with the advantages of shorter operating time, less morbidity, less pain, no scarring and easy revision of shape. But, usually the non-incision technique is recommended in the cases with thin upper eyelid, small amount of orbital fat, less redundant skin of upper eyelid and in whom a wide fold is not desired so on. Therefore, the disadvantages of this method are that it cannot be applied to all patients. The postoperative complications are disappearance or faded fold, formation of cyst or lumps, asymmetry etc. and the incidence of these complications is slightly higher than those of the incisional method. In this study, the double eyelid operation using the continuous buried suture method was performed in 210 patients for formation of double eyelid from Jan. 1993 to Dec. 1995. In conclusion very good results can be obtained by the continuous buried suture method even in the cases of puffy upper eyelid. This method can make a double eyelid shape in the fashion the patient wants and can be a new indication for correction of unilateral double eyelid. This method is safe, satisfactory and take shorter postoperative recovery time and it can reduce the incidence of postoperative complications.
Cicatrix ; Eyelids* ; Humans ; Incidence ; Orbit ; Postoperative Complications ; Skin ; Surgery, Plastic ; Sutures*

Many agents such as analgesics and sedatives have been used to decrease pain, anxiety and awareness during anesthesia. The effects of midazolam and propofol on cardiopulmonary functions and sedation were evaluated in a clinical study during spinal anesthesia. Thirty adult patients were received either midazolam 0.05mg/kg IV or propofol 1.25mg/kg IV after spinal anesthesia. Minute volume, arterial oxygen saturation, blood pressure, and heart rate were checked before and 20min after spinal anesthesia, as well as 2 min, 5 min, 10 min, 30 min, 60 min after each drug administration. The results were as follows ; 1) Minute volume and SaO2 were decreased from 2 min to 10 min in each group. 2) Mean arterial pressure was decreased from 2 min to 60 min in each group, but there was no significant difference between the two groups. Heart rate was increased at 2 min in propofol group 3) Recovery time from sedation was faster in the propofol group than the midazolam group. From the above results, we have concluded that midazolam and propofol have some effects on cardiopulmonary function and many advantages if used carefully during spinal anesthesia.
Adult ; Analgesics ; Anesthesia, Spinal* ; Anxiety ; Arterial Pressure ; Blood Pressure ; Heart Rate ; Humans ; Hypnotics and Sedatives ; Intraoperative Awareness ; Midazolam* ; Oxygen ; Propofol*

No abstract available.
Antistreptolysin* ; Child* ; Humans ; Reference Values* ; Seoul*

PURPOSE: To analyze clinical, radiological and pathological features as well as clinical outcome after surgical treatment of patients with secondary chondrosarcoma arising from osteochondroma(tosis). MATERIALS AND METHODS: We retrospectively reviewed clinical records, radiographs, pathologic slides of 14 patients. Nine patients were male and five were female. The mean age was 34 years. The mean follow-up period was 54 months. RESULTS: All patients had a history of previous mass since childhood or puberty. Preexisted osteochondroma was single in 3 patients and multiple in 10. Remaining 1 patient had multiple osteochondromatosis with enchondromatosis. MRI clearly provided thickness of cartilage cap, which was over 2 cm except in 2 cases. Chondrosarcoma was grade 1 in all except 1 case, which was grade 2. Wide excision was performed in 10 patients, marginal excision in 3 and amputation in 1. Twelve patients were doing very well without evidence of disease. Among 3 patients with marginal excision, 1 patient had local recurrence and 1 patient died of disease. CONCLUSION: Comprehensive understanding of clinical, radiological and pathological features of secondary chondrosarcoma is warranted for accurate diagnosis. The best result can be expected with early recognition of malignant change of osteohcondroma(tosis) and wide excision.
Amputation ; Cartilage ; Chondrosarcoma ; Enchondromatosis ; Female ; Follow-Up Studies ; Humans ; Male ; Osteochondroma ; Osteochondromatosis ; Puberty ; Recurrence ; Retrospective Studies

PURPOSE: To investigate prognostic factors influencing on local recurrence, distant metastasis and event-free survival of liposarcomas. MATERIALS AND METHODS: Fifty-two patients managed for liposarcomas since 1993 were analyzed respectively in the view of prognostic influence of patient age, tumor size, location, histologic type, histologic grade, resection type, surgical margin, chemotherapy and radiation therapy on local recurrence, distant metastasis and event-free survival. The mean follow up period was 39 months. The univariate and multivariate regression analysis were performed for statistical evaluation. RESULTS: The local recurrences occurred in 11 patients (21.2%) and distant metastasis in 4 patients (8%), Event-free survival rate at 4 year follow up was 67%. In univariate analysis, histologic grade, surgical margin, chemotherapy and radiation therapy were significant prognostic factors on local recurrence (p<0.05). However, histologic grade lost its significance in muitivariate analysis. Trunk location revealed higher rate of distant metastasis than extremity location. In univariate analysis on event-free survival. histologic grade and chemotherapy were significant factors (p<0.05). No factor remained significant in multivariate analysis. CONCLUSION: Considering selection bias, positive surgical margin was negative prognostic factor on local recurrence. Liposarcomas arisen in trunk revealed higher rate of distant metastasis. There was no independent prognostic factor on event-free survival of patients with liposarcomas.
Disease-Free Survival ; Extremities ; Follow-Up Studies ; Humans ; Liposarcoma ; Multivariate Analysis ; Neoplasm Metastasis ; Recurrence ; Retrospective Studies ; Selection Bias