1.Analysis of the functional domain of the hepatitis B virus X gene product fused to the GAL4 binding domain.
Byung Hyune CHOI ; Cheol Yong CHOI ; Geon Tae PARK ; Hyung Mo RHO
Journal of the Korean Society of Virology 1993;23(1):1-10
No abstract available.
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
2.Subcutaneous Granuloma Annulare of the Scalp: A case report.
Geon Kook LEE ; Joong Seok SEO ; Kye Yong SONG ; Seong Hye PARK ; Je G CHI ; Kyoung Chan PARK
Korean Journal of Pathology 1991;25(2):178-182
Subcutaneous granuloma annulare (SGA) is a rare, benign noninfectious histiocytic disease of unknown cause, characterized by necrobiosis of the connective tissue surrounded by infiltrates of histiocytes and lymphocytes. We report a case of SGA in a 49/12-year-old boy. The lesions were five nontender subcutaneous nodules in the parieto-occipital scalp, measuring 1.0 cm to 2.0 cm in diameter. Microscopical examination revealed variable stages of multiple necrobiotic areas, which showed central necrobiosis with palisading histiocytes, involving both the lower dermis and subcutaneous fatty tissue. Electron microscopic findings revealed many histiocytes in the necrobiotic areas with degenerating and necrotic collagen fibers as well as regenerating fibroblasts.
3.The Correlation between Anti-acetylcholine Receptor Antibody Titer and Clinical Grade in Myasthenia Gravis.
Yong Won CHO ; Jeong Geon LIM ; Young Choon PARK ; Il Kyu LEE
Journal of the Korean Neurological Association 1992;10(4):436-442
This study was performed to evaluate the titer of serum acetylcholine receptor antibody (AChR-Ab), the correlation between AChR-Ab titer and clinical state, clinical response to thymectomy and histopathologic finding of thymus in myasthenia gravis. Twenty-seven patients with various clinical grades of myasthenia gravis and twenty-three norrnal controls were included in this study. Mean AChR-Ab titers were 4.21+4.27nM in myasthenia gravis and 0.05+0.06nM in control group(p<0.05). Mean AChR-Ab titers of each clinical grade were 0.80+1.67nM in grade I, 5.05+3.42nN in grade Iia, 8.37+4.50nM in grade Iib, 6.67nM in grade m and 10.89nM in grade IV. There were significant correlation between clinical grade and level of AChR-AB titer. There were no correlation between degree of clinical improvement and changes of serum AChR-Ab titer after thymectomy in myasthenia gravis. There were also no correlation between level of AChR-Ab titers and histopathologic findings of thymus.
Acetylcholine
;
Humans
;
Myasthenia Gravis*
;
Thymectomy
;
Thymus Gland
4.The Correlation between Anti-acetylcholine Receptor Antibody Titer and Clinical Grade in Myasthenia Gravis.
Yong Won CHO ; Jeong Geon LIM ; Young Choon PARK ; Il Kyu LEE
Journal of the Korean Neurological Association 1992;10(4):436-442
This study was performed to evaluate the titer of serum acetylcholine receptor antibody (AChR-Ab), the correlation between AChR-Ab titer and clinical state, clinical response to thymectomy and histopathologic finding of thymus in myasthenia gravis. Twenty-seven patients with various clinical grades of myasthenia gravis and twenty-three norrnal controls were included in this study. Mean AChR-Ab titers were 4.21+4.27nM in myasthenia gravis and 0.05+0.06nM in control group(p<0.05). Mean AChR-Ab titers of each clinical grade were 0.80+1.67nM in grade I, 5.05+3.42nN in grade Iia, 8.37+4.50nM in grade Iib, 6.67nM in grade m and 10.89nM in grade IV. There were significant correlation between clinical grade and level of AChR-AB titer. There were no correlation between degree of clinical improvement and changes of serum AChR-Ab titer after thymectomy in myasthenia gravis. There were also no correlation between level of AChR-Ab titers and histopathologic findings of thymus.
Acetylcholine
;
Humans
;
Myasthenia Gravis*
;
Thymectomy
;
Thymus Gland
5.Pediatric Hip Disease (II): Developmental Dysplasia of the Hip – Treatment of Residual Dysplasia
Hui Taek KIM ; Yong Geon PARK ; Tae Young AHN
The Journal of the Korean Orthopaedic Association 2022;57(3):183-190
Residual dysplasia is common in spite of early treatment of developmental dysplasia of the hip and often requires a harness or femoral/ acetabular surgery. Operative treatment is roughly divided into two categories: reconstructive and salvage; but the reconstruction such as re-directional osteotomy of the acetabulum should always be considered first. Operative treatment consists of osteotomy on femur or acetabulum, or both. Before the surgery, thorough evaluation of the patient is necessary to select appropriate operation. Avascular necrosis is one of the most catastrophic complications, which is often seen in delayed diagnosis or surgically treated patients.
6.Erratum: Biofeedback Therapy Before Ileostomy Closure in Patients Undergoing Sphincter-Saving Surgery for Rectal Cancer: A Pilot Study.
Jeong Ki KIM ; Byeong Geon JEON ; Yoon Suk SONG ; Mi Sun SEO ; Yoon Hye KWON ; JI Won PARK ; Seung Bum RYOO ; Seung Yong JEONG ; Kyu Joo PARK
Annals of Coloproctology 2015;31(5):205-205
In this article, the sixth author's affiliation was misprinted unintentionally.
7.Bilateral Gluteal Necrosis and Deep Infection after Transarterial Embolization for Pelvic Ring Injury in Patient with Hemodynamic Instability: A Case Report
Sung Jin PARK ; Chang Ho JEON ; Nam Hoon MOON ; Yong Geon PARK ; Jae Hoon JANG
Journal of the Korean Fracture Society 2019;32(1):56-60
Transarterial embolization is accepted as effective and safe for the acute management in hemodynamically unstable patients with pelvic ring injury. However, transarterial embolization has potential complications, such as gluteal muscle/skin necrosis, deep infection, surgical wound breakdown, and internal organ infarction, which are caused by blocked blood flow to surrounding tissues and organs, and many studies on the complications have been reported. Here, we report an experience of the management of gluteal necrosis and infection that occurred after transarterial embolization, with a review of the relevant literature.
Hemodynamics
;
Humans
;
Infarction
;
Necrosis
;
Surgical Wound Infection
8.Progression of Peyronie's Disease during Tamoxifen Treatment.
Jinwook KIM ; Tae Il RHO ; Tae Yong PARK ; Soon Tae AHN ; Mi Mi OH ; Du Geon MOON
Korean Journal of Andrology 2012;30(1):52-56
PURPOSE: Medical treatment of Peyronie's disease with tamoxifen has been initially proposed as acting upon the early phase of the disease. As recent reports show no significant benefit of tamoxifen, we review the long term results of tamoxifen treatment of Peyronie's disease. MATERIALS AND METHODS: Time to progression during tamoxifen treatment of patients showing acute disease and chronic disease was compared. The acute phase was identified by pain during erection. Progression was defined as enlargement of plaque size or appearance of calcification. RESULTS: The average treatment duration was 15.9+/-13.8 months (range: 3 to 48 months). The median time to progression was 7 months for acute patients and 20 months for chronic patients. Eighty percent of patients in the acute phase showed relief of pain; however, overall progression was 72.1% (78.0% for acute, 66.7% for chronic). Patient history, comorbidities, serum testosterone or initial plaque characteristics, and severity of curvature were not predictive of disease progression. CONCLUSIONS: Tamoxifen showed no significant benefit in slowing the progression of Peyronie's disease in the acute phase over the chronic phase. Peyronie's disease continued to progress, though at a dampened rate for patient's in the chronic phase.
Acute Disease
;
Chronic Disease
;
Comorbidity
;
Humans
;
Male
;
Penile Induration
;
Tamoxifen
;
Testosterone
9.Papular Elastorrhexis in Down's Syndrome.
Hyun Chul SHIM ; Young In JEONG ; Geon KIM ; Kye Yong SONG ; Jong Eun LEE ; Minh Sook JUE ; Eun Jung KIM ; Hyang Joon PARK ; Ok Ja JOH
Korean Journal of Dermatology 2013;51(9):750-752
No abstract available.
Down Syndrome
10.Effects of rehydration fluid temperature and composition on body weight retention upon voluntary drinking following exercise-induced dehydration.
Sung Geon PARK ; Yoon Jung BAE ; Yong Soo LEE ; Byeong Jo KIM
Nutrition Research and Practice 2012;6(2):126-131
The purpose of this study was to determine the effects of beverage temperature and composition on weight retention and fluid balance upon voluntary drinking following exercise induced-dehydration. Eight men who were not acclimated to heat participated in four randomly ordered testing sessions. In each session, the subjects ran on a treadmill in a chamber maintained at 37degrees C without being supplied fluids until 2% body weight reduction was reached. After termination of exercise, they recovered for 90 min under ambient air conditions and received one of the following four test beverages: 10degrees C water (10W), 10degrees C sports drink (10S), 26degrees C water (26W), and 26degrees C sports drink (26S). They consumed the beverages ad libitum. The volume of beverage consumed and body weight were measured at 30, 60, and 90 min post-recovery. Blood samples were taken before and immediately after exercise as well as at the end of recovery in order to measure plasma parameters and electrolyte concentrations. We found that mean body weight decreased by 1.8-2.0% following exercise. No differences in mean arterial pressure, plasma volume, plasma osmolality, and blood electrolytes were observed among the conditions. Total beverage volumes consumed were 1,164 +/- 388, 1,505 +/- 614, 948 +/- 297, and 1,239 +/- 401 ml for 10W, 10S, 26W, and 26S respectively (P > 0.05). Weight retention at the end of recovery from dehydration was highest in 10S (1.3 +/- 0.7 kg) compared to 10W (0.4 +/- 0.5 kg), 26W (0.4 +/- 0.4 kg), and (0.6 +/- 0.4 kg) (P < 0.005). Based on these results, carbohydrate/electrolyte-containing beverages at cool temperature were the most favorable for consumption and weight retention compared to plain water and moderate temperature beverages.
Arterial Pressure
;
Beverages
;
Body Weight
;
Dehydration
;
Drinking
;
Electrolytes
;
Fluid Therapy
;
Hot Temperature
;
Humans
;
Male
;
Osmolar Concentration
;
Plasma
;
Plasma Volume
;
Retention (Psychology)
;
Sports
;
Water
;
Water-Electrolyte Balance