1.Application of Osteotomies in Aesthetic Rhinoplasty.
Jae Yong JEONG ; Hyun Woo KYUNG ; Sang Ha OH ; Nak Heon KANG ; Yong Ah RYU
Journal of the Korean Society of Aesthetic Plastic Surgery 2010;16(1):15-20
Nasal osteotomy for aesthetic results is required in patients who have broad nasal bone. Since the procedure is difficult, many operators hesitate the surgery. From January 2007 to July 2009, we performed 77 cases of nasal osteotomy, consisting of paramedian oblique medial osteotomy or median oblique-medial osteotomy and percutaneous lateral osteotomy. Most of the patients had satisfying results, however three patients had asymmetric shape and inappropriate inward movement of nasal bone which required revision with percutaneous lateral osteotomy. Osteotomy procedure varies, depending on surgeon's preference and experience, however, each surgeon should be aware of good and weak points of those procedures and use the most suitable method. In order to achieve maximal satisfying results, preoperative analysis of patients and minimal invasive handling should be done. Based on these efforts, this method could broadly be used in the aesthetic field.
Handling (Psychology)
;
Humans
;
Nasal Bone
;
Nose
;
Osteotomy
;
Rhinoplasty
2.Histological, Physical Studies after Xenograft of Porcine Ear Cartilage.
Yong Ah RYU ; Meiying JIN ; Nakheon KANG
Archives of Craniofacial Surgery 2017;18(3):155-161
BACKGROUND: Because of the relatively similar size of organs to human and the physiological and structural similarities, the use of porcine as xenograft donors is progressing very actively. In this study, we analyzed the characteristics of porcine ear cartilage and evaluated its suitability as graft material in reconstructive and cosmetic surgery. METHODS: The auricular cartilage was harvested from two pigs, and subjected to histological examination by immunohistochemical staining. To determine the collagen content, samples were treated with collagenase and weight changes were measured. After sterilization by irradiation, the samples were grafted into rats and stained with Hematoxylin and Eosin and Masson Trichrome to observe inflammation and xenograft rejection. RESULTS: In IHC staining, extracellular matrices were mainly stained with type II collagen (20.69%), keratin sulfate (10.20%), chondroitin sulfate (2.62%), and hyaluronic acid (0.84%). After collagenase treatment, the weight decreased by 68.3%, indicating that about 70% of the porcine ear cartilage was composed of collagen. Upon xenograft of the sterilized cartilages in rats, inflammatory cells were observed for up to 2 months. However, they gradually decreased, and inflammation and reject-response were rarely observed at 5 months. CONCLUSION: The porcine ear cartilage was covered with perichondrium and cellular constituents were found to be composed of chondrocytes and chondroblasts. In addition, the extracellular matrices were mainly composed of collagen. Upon xenograft of irradiated cartilage into rats, there was no specific inflammatory reaction around the transplanted cartilage. These findings suggest that porcine ear cartilage could be a useful alternative implant material for human cosmetic surgery.
Animals
;
Cartilage
;
Chondrocytes
;
Chondroitin Sulfates
;
Collagen
;
Collagen Type II
;
Collagenases
;
Ear Cartilage*
;
Ear*
;
Eosine Yellowish-(YS)
;
Extracellular Matrix
;
Hematoxylin
;
Heterografts*
;
Humans
;
Hyaluronic Acid
;
Inflammation
;
Rats
;
Sterilization
;
Surgery, Plastic
;
Swine
;
Tissue Donors
;
Transplants
3.Clinical Experience of Hyperfibrosis Occurred after Silicone Implant Insertion.
Yong Ah RYU ; Hyung Soo KIM ; Ki Ho LEE ; Seung Ryul LEE ; Nak Heon KANG
Journal of the Korean Cleft Palate-Craniofacial Association 2004;5(2):137-140
Facial depression is not rare conditions caused by soft tissue loss or bone distortion. In such conditions, autogenous bone, cartilage and bioacceptible materials are used for soft tissue augmentation. De Nicola used silicone rubber implant first in 1950. That after, silicone implants are used for bone defect and soft tissue augmentation. We experienced 31-year-old male patient who injured open depressed fracture of right temporal bone. He was operated with autogenous bone graft for bone defect area and silicone implants for soft tissue augmentation. After about 6 years later, mass palpated in right temporal area. There was no inflammatory sign in physical examination and CT finding. So we removed hyperfibrotic tissue totally with previous inserted silicone implants and augmented soft tissue with pored Medpor(R) block. In light microscopic findings, only tissue hyperfibrosis were proved without inflammatory cell, such as giant cell or ephithelioid cell.
Adult
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Cartilage
;
Depression
;
Giant Cells
;
Humans
;
Male
;
Physical Examination
;
Silicone Elastomers
;
Temporal Bone
;
Transplants
4.Delayed Orbital Hemorrhage around Alloplastic Implants after Blowout Fracture Reduction.
Yong Ah RYU ; Jae Beom PARK ; Hyun Woo KYUNG ; Seung Han SONG ; Nak Heon KANG
Archives of Craniofacial Surgery 2015;16(1):35-38
Alloplastic implants have been used to repair orbital wall fractures in most cases. Orbital hemorrhage is a rare complication of these implants and has been reported rarely in Korea. The purpose of this article is to report a late complication case focusing on their etiology and management. A 20-year-old male patient underwent open reduction with Medpor (porous polyethylene) insertion for bilateral orbital floor fractures. The initial symptom occurred with proptosis in the right side as well as vertical dystopia, which had started 4 days earlier, 8 months after surgery. Any trauma history after the surgery was not present. We performed an exploration and removal of hematoma with Medpor titanium meshed alloplastic implant. A case of delayed orbital hematoma following alloplastic implant insertion was identified. It occurred within the pseudocapsule of the implant. One week after surgery, overall symptoms improved successfully, and no complications were reported during the 11-month follow-up period. Although rare, orbital hemorrhage is a potential complication of alloplastic orbital floor implants, which may present many years after surgery. As in the case presented, delayed hematoma should be included in the differential diagnosis of late proptosis or orbital dystopia.
Diagnosis, Differential
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Exophthalmos
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Follow-Up Studies
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Hematoma
;
Hemorrhage*
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Humans
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Korea
;
Male
;
Orbit*
;
Titanium
;
Young Adult
5.Does Transurethral Resection Affect the Results of Computed Tomography in the Clinical Staging of Invasive Bladder Cancer?.
Jin Rae ROH ; Jeong Ah RYU ; Bohyun KIM ; Soo Eung CHAI ; Han Yong CHOI
Korean Journal of Urology 2002;43(3):219-223
Purpose: Computed tomography (CT) is commonly used for the clinical staging of bladder cancer. However, a previous transurethral resection (TUR) often results in an overestimation of a proper muscle and perivesical fat invasion in the CT. The purpose of this study was to evaluate the effects of a TUR on CT staging in patients with bladder cancer. MATERIALS AND METHODS: A total of 67 patients who underwent a radical cystectomy for primary bladder cancer were included in this study. CT was performed before a TUR in 38 patients (group 1) and after a TUR in 29 (group 2). In each patient, CT evaluated the presence or absence of a proper muscle and perivesical fat invasion and the findings were then compared with the histopathologic findings following the radical cystectomy. RESULTS: CT had an overall staging accuracy of 79.1% for a proper muscle invasion and 67.2% for a perivesical fat invasion. For a proper muscle invasion, there was a significant difference between both groups in the CT specificity (76.9% vs. 30.0%, p=0.024) while no difference in the sensitivity (92.0% vs. 89.5%) was noted. For a perivesical fat invasion, there was also a significant difference between the two groups in terms of the CT specificity (75.0% vs. 35.7%, p=0.022) while there was no difference in the sensitivity (72.2% vs. 80.0%). CONCLUSIONS: A TUR before a CT may cause a false positive result in the clinical staging of bladder cancer using CT. Therefore, to minimize the confounding effect of a TUR on CT staging, it is strongly recommended that a CT be performed before a TUR in the case of a highly suspicious invasive bladder cancer.
Cystectomy
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Humans
;
Neoplasm Staging
;
Sensitivity and Specificity
;
Urinary Bladder Neoplasms*
;
Urinary Bladder*
6.Sebaceous Carcinoma Treated with Various Flaps in Head and Facial Regions.
Da Arm KIM ; Yong Ah RYU ; Nak Heon KANG ; Sang Ha OH
Journal of the Korean Cleft Palate-Craniofacial Association 2010;11(1):58-61
PURPOSE: Sebaceous carcinoma is a rare malignant tumor that occurs mostly in head and neck regions. Early diagnosis and treatment are necessary because it tends to be locally aggressive and goes through distal metastasis with fast progression. This study presents reliable surgical methods for sebaceous carcinoma in head and neck regions. METHODS: Three patients were included in this study. First, a 61-year-old woman visited the hospital with a yellow-colored, slowly growing mass on the left ala. A 54-year-old woman had a brown-colored mass on her right preauricle. Last case was a 62-year-old man who had a yellow-colored mass on his scalp. CT scan and punch biopsy were done. All cases were diagnosed as sebaceous carcinoma. The lesions were resected with 10 mm safety margin and various regional flaps were used for reconstruction. RESULTS: Histological examination revealed sebaceous differentiation and local invasions. Postoperatively, all patients did not suffer from complication and no recurrence was found. CONCLUSION: We recommend early wide excision with an enough safety margin, and a regional flap as a treatment of sebaceous carcinoma.
Biopsy
;
Early Diagnosis
;
Female
;
Head
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Humans
;
Middle Aged
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Neck
;
Neoplasm Metastasis
;
Recurrence
;
Scalp
7.Comparison of Methods for Collecting Saliva for Pepsin Detection in Patients with Laryngopharyngeal Reflux.
In Yong RYU ; Ah Ra JUNG ; Jung Min PARK ; Young Chan LEE ; Young Gyu EUN
Korean Journal of Otolaryngology - Head and Neck Surgery 2017;60(11):570-574
BACKGROUND AND OBJECTIVES: To compare the simple spitting method and the Salivette® method of collecting saliva for detecting pepsin in patients with laryngopharyngeal reflux disease (LPRD). SUBJECTS AND METHOD: Thirty-two patients diagnosed with LPRD by 24 hour multichannel intraluminal impedance and pH monitoring were enrolled prospectively. The amounts of pepsin in saliva determined by the simple spitting method and the Salivette® method were compared. RESULTS: Simple spitting showed higher sensitivity, specificity, accuracy, positive predictive value and negative predictive value. There was no statistically significant difference between the amount of pepsin detected by simple spitting (10.07±11.68 ng/mL) versus that detected using the Salivette® method (7.09±7.27 ng/mL) (p=0.258). CONCLUSIONS: The simple spitting method has higher sensitivity, specificity and accuracy than the Salivette® method for detecting pepsin in patients with LPRD.
Electric Impedance
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Humans
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Hydrogen-Ion Concentration
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Laryngopharyngeal Reflux*
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Methods*
;
Pepsin A*
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Prospective Studies
;
Saliva*
;
Sensitivity and Specificity
8.Cationic Trypsinogen Gene Mutation in Patients with Chronic Idiopathic Pancreatitis.
Woo Jin LEE ; Kyung Ah KIM ; June Sung LEE ; Young Bin JEON ; Ji Bong JEONG ; Ji Kon RYU ; Yong Tae KIM ; Yong Bum YOON ; Chung Yong KIM
The Korean Journal of Gastroenterology 2004;43(1):41-46
BACKGROUND/AIMS: Mutation of Cationic trypsinogen gene is clearly associated with hereditary pancreatitis and plays an important role in the pathogenesis of pancreatitis. According to literature, this mutation is occasionally occurred in patients with pancreatitis in Western countries and Japan. The aim of this study was to find out whether the mutation was observed in Korean patients with chronic idiopathic pancreatitis. METHODS: Peripheral blood samples of 11 patients with chronic idiopathic pancreatitis were collected consecutively, and DNA was extracted from the samples. Polymerase chain reaction was performed in exon 2 and 3 of cationic trypsinogen gene. Then, DNA products were purified and sequenced. RESULTS: The mutation was not found in exon 2 and 3 of cationic trypsinogen gene in these patients. CONCLUSIONS: There was no cationic trypsinogen mutation in Korean patients with chronic idiopathic pancreatitis. Further large sampled cohort study is needed.
Adolescent
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Adult
;
Chronic Disease
;
English Abstract
;
Female
;
Humans
;
Male
;
Middle Aged
;
*Mutation
;
Pancreatitis/*genetics
;
Polymerase Chain Reaction
;
Trypsin/*genetics
;
Trypsinogen/*genetics
9.Clinical Characterization of Reverse Redistribution Pattern in 99mTC-Sestamibi Myocardial Perfusion Scan.
Byung Chun CHUNG ; Jae Kean RYU ; Yong Keun CHO ; Dong Hoon KWACK ; Ho Sang BAE ; Yong Hak BAE ; Kyung Ah CHUN ; Shung Chull CHAE ; Jae Eun JUN ; Wee Hyun PARK ; Jae Tae LEE
Korean Circulation Journal 1999;29(5):459-464
BACKGROUND AND OBJECTIVES: Reverse redistribution pattern (RRP), that is defined as the worsening of the perfusion defect at rest image, can be observed in 99mTC-sestamibi (methoxy isobutyl isonitrile) myocardial scan with standard stress-rest protocol. This study was prepared to evaluate the prevalence and clinical characteristics of RRP in stress 99mTc-sestamibi myocardial scan. MATERIALS AND METHODS: We retrospectively reviewed 1304 images of 99mTC-sestamibi myocardial perfusion scan performed between January 1995 and June 1997, and scintigraphic findings were compared with clinical and angiographic data. RESULTS: The prevalence of RRP was 5.2%(68 of 1,304). RRP was noted in 6.0% (41 of 679) of the adenosine study and 4.3% (27 of 625) of the exercise study. The mean coronary artery stenosis at RRP territory was 51.5+/-38.9%. However, normal coronary artery at RRP territory was noted in 45.8% (11 of 24). There was no significant differences in luminal narrowing of coronary arteries, TIMI flow grade and LV wall motion between the patient with RRP positive and RRP negative at the infarct related artery territory. CONCLUSION: Reverse redistribution pattern on 99mTC-sestamibi myocardial SPECT does not seem to indicate the presence of significant coronary artery disease or patency of the infarct related arteries in the patients with acute MI.
Adenosine
;
Arteries
;
Coronary Artery Disease
;
Coronary Stenosis
;
Coronary Vessels
;
Humans
;
Perfusion*
;
Phenobarbital
;
Prevalence
;
Retrospective Studies
;
Technetium Tc 99m Sestamibi*
;
Tomography, Emission-Computed, Single-Photon
10.Comparative Observation of Barrier Sheet and Nonbarrier Sheet Medpor(R) Inserted on Orbital Floor in Rabbits.
Hyung Soo KIM ; Yong Ah RYU ; Jong Seol WOO ; Ki Ho LEE ; Nak Heon KANG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2004;31(5):682-686
The purpose of this study was to determine the histopathologic change of Medpor(R) implant for the case of orbital floor reconstruction in the rabbit model. Two types of Medpor(R)(barrier sheet and nonbarrier sheet) were used for the reconstruction of orbital floor in 30 rabbits. In 1 month and 6 months postoperatively, the histopathologic changes were observed with light microscope and forced duction test was performed. None of the implants were lost or extruded and there was no evidence of wound infection, hematoma, or seroma formation. None of cases showed positive in force duction test. Orbital tissue ingrowth was not observed in the barrier sheet Medpor(R) implant group, however, it was observed in the nonbarrier sheet Medpor(R) implant group. This study supports that the barrier sheet Medpor(R) may more suitable than nonbarrier sheet Medpor(R) for reconstruction of the fractured orbital wall.
Hematoma
;
Orbit*
;
Rabbits*
;
Seroma
;
Wound Infection