1.Clinical Report of Effects of Pre and Post-partum Thyroiditis (PPT).
Yong Wook CHO ; Myung Seo KANG ; Young Soo CHA ; Jin Hwan KOOK ; Yoo Ri KIM ; Pil Won PARK ; Wee Hyun LEE ; Jung Eun LIM ; Yo Won CHO
Journal of Korean Society of Endocrinology 1997;12(4):541-549
BACKGROUND: Excessive iodine intake increases the occurrence of autoimmune thyroid disorders by enhancing immunogenecity of iodine-rich thyroglobulin, In Korea, most of postpartum women take a large amount of iodine-rich seaweed. Although the excessive iodine intake may affect the thyroid function, only a few reports were available concering iodine intake, especially on postpartum period. METHODS: A prospective study was undertaken in 146 of normal delivered postpartum women. Dietary intake and urinary excretion of iodine, serum T3, T4, TSH, anti-TPO Ab and anti-Tg Ab were measured before and 1, 6, 12 and 24 weeks after delivery. Iodine intake was analyzed by one-to-one interview using 24hr recall and food frequency questionnaire. RESULTS: 1. PPT was occurred in 6 (10.3%) postparturn women, It presented as hypothyroidism alone in 1 (16.7%), transient thyrotoxicosis followed by hypothyroidisrn in 3 (50.0%), and thyrotoxicosis alone in 2 (33.3%) of the follwed-up patients. 2. During pregnancy, no difference was found in age, serum T3, T4 and TSH between PPT and normal thyroid function group. 3. In PPT group, anti-TPO and anti-Tg Ab were significantly higher than those of normal thyroid function group during pregnancy, and their sensitivity for PPT was 40% and 33%, respectively. But there was no correlation between dietary iodine intake and the titer of thyroid auto-antibodies. 4. There was no correlation between pre and post-partum dietary iodine intake and occurrence of PPT. CONCLUSION: In Korea, the incidence of PPT was slightly higher than other nations. The sensitivity of thyroid auto-antibodies was too low to use for prediction of PPT. Pre and post-partum iodine intake had no effect on the occurrence of PPT and post-partum thyroid function.
Female
;
Humans
;
Hypothyroidism
;
Incidence
;
Iodine
;
Korea
;
Postpartum Period
;
Postpartum Thyroiditis*
;
Pregnancy
;
Prospective Studies
;
Surveys and Questionnaires
;
Seaweed
;
Thyroglobulin
;
Thyroid Gland
;
Thyrotoxicosis
2.Effect of Percutaneous Transluminal Coronary Angioplasty in Treatment of Cardiogenic Shock Complicating Acute Myocardial Infarction.
Joon Han SHIN ; Seung Jea TAHK ; Han Soo KIM ; Won KIM ; Dong Jin KIM ; Sung Hyon KU ; Yo Han CHO ; So Yeon CHOI ; Byung II CHOI
Korean Circulation Journal 1996;26(6):1091-1098
BACKGROUND: Cardiogenic shock is the most common cause of in-hospital mortality after acute myocardial infarction. Despite improvement in coronary care, the in-hospital mortality rate of cardiogenic shock is very high in conventional conservative therapy. Recently, it was suggested that coronary angioplasty may reduce the mortality associated with cardiogenic shock. METHOD: Thirteen consecutive patients with cardiogenic shock who underwent coronary angioplasty were studied. Shock was not induced by mechanical complications, arrhythmia, hypovolemia and other reversible cause. We collected and analyzed the clinical, hemodynamic survivor groups. RESULTS: Of 13 patients, 11 had successful reperfusion of the infarct-related coronary artery and 2 had unsuccessful reperfusion. Of 11 patients with successful angioplasty, 8 survived at the time of hospital discharge. All patents with unsuccessful angioplasty died in the hospital. Therefore overall hospital survival rate was 62% and the rate increased to 73% in patients with successful reperfusion. Survivor and non-survivor groups in clinical, hemodynamic and angiographic variables were similar except systolic blood pressure and the presence of successful reperfusion. CONCLUSION: In patients with cardiogenic shock, the patency of infarct-related coronary artery was strongly associated with in-hospital mortality. This findings support aggressive interventional strategy in patient with cardiogenic shock complicating acute myocardial infarction.
Angioplasty
;
Angioplasty, Balloon, Coronary*
;
Arrhythmias, Cardiac
;
Blood Pressure
;
Coronary Vessels
;
Hemodynamics
;
Hospital Mortality
;
Humans
;
Hypovolemia
;
Mortality
;
Myocardial Infarction*
;
Reperfusion
;
Shock
;
Shock, Cardiogenic*
;
Survival Rate
;
Survivors
3.Effect of Percutaneous Transluminal Coronary Angioplasty in Treatment of Cardiogenic Shock Complicating Acute Myocardial Infarction.
Joon Han SHIN ; Seung Jea TAHK ; Han Soo KIM ; Won KIM ; Dong Jin KIM ; Sung Hyon KU ; Yo Han CHO ; So Yeon CHOI ; Byung II CHOI
Korean Circulation Journal 1996;26(6):1091-1098
BACKGROUND: Cardiogenic shock is the most common cause of in-hospital mortality after acute myocardial infarction. Despite improvement in coronary care, the in-hospital mortality rate of cardiogenic shock is very high in conventional conservative therapy. Recently, it was suggested that coronary angioplasty may reduce the mortality associated with cardiogenic shock. METHOD: Thirteen consecutive patients with cardiogenic shock who underwent coronary angioplasty were studied. Shock was not induced by mechanical complications, arrhythmia, hypovolemia and other reversible cause. We collected and analyzed the clinical, hemodynamic survivor groups. RESULTS: Of 13 patients, 11 had successful reperfusion of the infarct-related coronary artery and 2 had unsuccessful reperfusion. Of 11 patients with successful angioplasty, 8 survived at the time of hospital discharge. All patents with unsuccessful angioplasty died in the hospital. Therefore overall hospital survival rate was 62% and the rate increased to 73% in patients with successful reperfusion. Survivor and non-survivor groups in clinical, hemodynamic and angiographic variables were similar except systolic blood pressure and the presence of successful reperfusion. CONCLUSION: In patients with cardiogenic shock, the patency of infarct-related coronary artery was strongly associated with in-hospital mortality. This findings support aggressive interventional strategy in patient with cardiogenic shock complicating acute myocardial infarction.
Angioplasty
;
Angioplasty, Balloon, Coronary*
;
Arrhythmias, Cardiac
;
Blood Pressure
;
Coronary Vessels
;
Hemodynamics
;
Hospital Mortality
;
Humans
;
Hypovolemia
;
Mortality
;
Myocardial Infarction*
;
Reperfusion
;
Shock
;
Shock, Cardiogenic*
;
Survival Rate
;
Survivors
4.A case of sideroblastic anemia caused by lead-containing herbal medication.
Hyun Sik PARK ; Sung Young KIM ; Jin Hee CHO ; Hee Won MOON ; So Young YOON ; Yo Han CHO ; Mark Hong LEE
Korean Journal of Medicine 2010;79(4):448-452
Although lead intoxication is commonly mentioned as a cause of sideroblastic anemia, no well-documented case exists in the literature. We encountered a patient with sideroblastic anemia caused by lead-containing herbal medicine. A 34-year-old woman was admitted to our hospital with abdominal pain. She had taken herbal medicine for her general health. Anemia, hyperbilirubinemia, and elevated lactic dehydrogenase were found from the laboratory data. Bone marrow biopsy showed pathological ringed sideroblasts. Her serum level of lead was high and the lead content of the tablet was higher than permitted. We diagnosed her with sideroblastic anemia secondary to lead poisoning caused by herbal medicine. We stopped her from taking herbal medicine and she gradually recovered from anemia.
Abdominal Pain
;
Adult
;
Anemia
;
Anemia, Sideroblastic
;
Biopsy
;
Bone Marrow
;
Female
;
Herbal Medicine
;
Humans
;
Hyperbilirubinemia
;
Lead Poisoning
;
Oxidoreductases
5.A Case of Vulvar Milium-like Syringoma in a Child Treated with Tranilast.
Won Joo KWON ; Yo Sup SHIN ; Bok Won PARK ; Eun Byul CHO ; Eun Joo PARK ; Kwang Ho KIM ; Kwang Joong KIM
Korean Journal of Dermatology 2017;55(8):526-528
Syringoma is the most common type of benign intraepidermal eccrine sweat gland tumor in Korea, and is usually found in women in their forties. It presents mostly as a localized lesion, preferring the lower eyelid, cheek, or forehead, and rarely invades the vulval area, and in the case of children, vulvar invasion is even more rare. Tranilast is an antihistamine used for atopic dermatitis and asthma, and has recently been used for the treatment of keloid. A few previous studies have reported both localized and generalized forms of syringoma being effectively resolved with tranilast. Herein, we report a rare and interesting case of milium-like syringoma, which manifested on the vulval area of 10-year old girl that was successfully treated with tranilast.
Asthma
;
Cheek
;
Child*
;
Dermatitis, Atopic
;
Eyelids
;
Female
;
Forehead
;
Humans
;
Keloid
;
Korea
;
Sweat Glands
;
Syringoma*
;
Vulva
7.Effects of Calcium Antagonists on the PC12 Cell Damage Induced by Hypoxia.
Byeong Chae KIM ; Ki Chun SHIN ; Jun Ho SON ; Yo Sik KIM ; Ki Hyun CHO ; Won Yeup BAE ; Kee Young LEE ; Sei Jong KIM
Journal of the Korean Neurological Association 1995;13(1):1-10
Hypoxia-induced cell damage is known to be mediated by increase in intracellular calcium. In the present study, the effect of calcium channel blockers on the hypoxia-induced cell damage was investigated in iat pheochromocytoma cells line, PC12 cells. The cultured cells were exposed to hypoxia under 95% N2 plus 5% C02 gas phase and incubated in the media devoid of fetal bovine seruril The cell demage was assessed by measuring the release of lactate dehydrogenase (LDH) from the cells into the incubation media. Exposure of the cells to hypoxia for 2 hours caused a 28% of the total LDH to be released from cells -into media. The pretreatment of the cells with 1 mM each of diltiazem, nifedipine, and verapamil depressed the LDH release to the extent of 52%, 42%, and 30% inhibition, respectively. The inhibitory effects of diltiazem and verapamil were more marked at 1 mM than at 10 mM. The influx of 45 Ca2+ into the cells was rapidly increased within 2 minutes after exposure of the cells to hypoxia. Diltiazem at 1 mM almost completely inhibited Ca2+ influx, while nifedipine and verapamil exhibited only, 30% inhibition of Ca2- influx. The results lend support to the notion that mcreased intracellular calcium triggers a series of cascade reactions leadmg to cell death. It is suggested that the inhibitory effects of various calcium antagonists on hypoxia-induced cell damage differ from each other in their potency.
Animals
;
Anoxia*
;
Calcium Channel Blockers
;
Calcium*
;
Cell Death
;
Cells, Cultured
;
Diltiazem
;
L-Lactate Dehydrogenase
;
Nifedipine
;
PC12 Cells*
;
Pheochromocytoma
;
Verapamil
8.A Case of Malignant Duodenocolic Fistula.
Sei Won KIM ; Hiun Suk CHAE ; Jeong Yo MIN ; Hye Suk SON ; Jin Su KIM ; Hyung Keun KIM ; Young Seok CHO ; Chang Hyuk AHN
Korean Journal of Gastrointestinal Endoscopy 2009;38(1):38-42
Malignant duodenocolic fistula is a rare complication of colon cancer, and this usually develops as the right-side colon cancer or colonic hepatic flexure cancer infiltrates into the second portion of the duodenum. Six Korean cases of this malignancy have been previously reported on. The patients usually complain of watery diarrhea, feculant vomiting and weight loss that can be attributed to the altered normal flora. Barium enema has been the diagnostic procedure of choice to demonstrate the fistulous tract, but with the technical development of gastroendoscopy, the primary procedure is also changing. Curative resection is not possible in many cases. Palliative ileotransverse colostomy with gastrodjejunostomy is performed to relieve symptoms, but it cannot completely prevent the vomiting or diarrhea. We herein present a case of malignant duodenocolic fistula in a patient who had been suffering from indigestion, loose stool and feculant vomiting for one year. This case was diagnosed by endoscopy and the patient underwent a palliative operation.
Barium
;
Colon
;
Colonic Neoplasms
;
Colostomy
;
Diarrhea
;
Duodenum
;
Dyspepsia
;
Endoscopy
;
Enema
;
Fistula
;
Humans
;
Stress, Psychological
;
Vomiting
;
Weight Loss
9.Pneumocystis carinii pneumonia in gastric cancer patients without acquired immune deficiency syndrome: 3 cases report and literature review.
So Young YOON ; Hyun Kyun KI ; Sung Yong KIM ; Yo Han CHO ; Hong Ghi LEE ; Moon Won YOO
Journal of the Korean Surgical Society 2012;83(1):50-55
Pneumocystis carinii pneumonia (PCP) has rarely been reported in solid tumor patients. It is a well-known complication in immunosuppressed states including acquired immune deficiency syndrome and hematologic malignancy. PCP has been reported in solid tumor patients who received long-term steroid treatment due to brain or spinal cord metastases. We found 3 gastric cancer patients with PCP, who received only dexamethasone as an antiemetic during chemotherapy. The duration and cumulative dose of dexamethasone used in each patient was 384 mg/48 days, 588 mg/69 days, and 360 mg/42 days, respectively. These cases highlight that the PCP in gastric cancer patients can successfully be managed through clinical suspicion and prompt treatment. The cumulative dose and duration of dexamethasone used in these cases can be basic data for risk of PCP development in gastric cancer patients during chemotherapy.
Acquired Immunodeficiency Syndrome
;
Brain
;
Dexamethasone
;
Hematologic Neoplasms
;
Humans
;
Neoplasm Metastasis
;
Pneumocystis
;
Pneumocystis carinii
;
Pneumonia, Pneumocystis
;
Spinal Cord
;
Stomach Neoplasms
10.Obstructive uropathy after inguinal herniorrhaphy with a mesh in a renal transplant patient.
Jung Min PARK ; Mun Ju HWANG ; Yo Han JEONG ; Seok Hui KANG ; Kyu Hyang CHO ; Jong Won PARK ; Jun Young DO ; Kyung Woo YOON ; Nam Hyuk LEE
Kidney Research and Clinical Practice 2013;32(2):72-73
A 67-year-old male renal transplant patient presented with a right inguinal bulging mass, and was diagnosed with a right indirect inguinal hernia. The day following inguinal herniorrhaphy, serum creatinine became elevated. The patient was oliguric and had abdominal pain on the first day after inguinal herniorrhaphy with a mesh. We diagnosed him with acute renal failure and subsequently performed acute hemodialysis. The kidney computed tomography showed hydronephroureter, with distal ureter obstruction. With urgent percutaneous nephrostomy, we were able to relieve the obstructive uropathy with distal ureteral stenosis. Subsequently, hernia repair was performed with removal of the mesh, followed by the antegrade ureteral stent insertion. Renal function was recovered after ureteral stent insertion. This case shows that acute renal failure can occur due to ureteral obstruction, complicated by an inguinal hernia repair, and this can be successfully treated with percutaneous nephrostomy and inguinal hernia repair with mesh removal.
Abdominal Pain
;
Acute Kidney Injury
;
Aged
;
Constriction, Pathologic
;
Creatinine
;
Hernia, Inguinal
;
Herniorrhaphy
;
Humans
;
Kidney
;
Male
;
Nephrostomy, Percutaneous
;
Renal Dialysis
;
Stents
;
Transplants
;
Ureter
;
Ureteral Obstruction