Fuzheng Yiai Infusion is an effective remedy for micro - residual leukemia (MRL). It yields marked mitigation on the geneval condition of the patient and prevents complications by substantially improves the patients immunity, elevates the rate of total remission and living quality, prolongs the survival period. Studies on the indices including DNA index, rate of DNA non - uneuploid, ph' chromosome, and BCR/ ABL gene, showed that the recipe can inhibit or eliminate the actions of malignant clone. In vitro cultivation of cells proved that the recipe yields stimulating action on the proliferation of normal marrow cells, yet yields no stimulating action on leukemic cells. Animal experiments reveal this recipe markedly prolongs the survival period of MRL animal models.

OBJECTIVE:To provide reference for rational use of glucocorticoid in the clinic. METHODS:The glucocorti-coid outpatient prescriptions collected from clinical departments of a hospital during Jan. 2013 to Jun. 2015 were analyzed statisti-cally in respects of glucocorticoid use,department distribution,DDDs,distribution of prescription diagnosis,etc. RESULTS:Of 15 000 prescriptions,there were 1 562 glucocorticoid prescriptions,with utilization rate of 10.4%;189 prescriptions were recog-nized as irrational ones,with irrational rate of 12.1%. The proportion of glucocorticoid in otorhinolaryngology department was the highest(27.66%),and irrational drug use was the highest in pediatrics department(16.12%);Dexamethasone injection was the most widely applied(44.88%);most of glucocorticoid prescriptions were used for acute bronchitis and bronchitis(267 pre-scriptions). CONCLUSIONS:The irrational glucocorticoid application has existed in the hospital,which deserved special atten-tion. Hence,prescription check and evaluation should be strengthened to promote the safety and efficacy of glucocorticoid in clini-cal application.

OBJECTIVE:To analyze the application of drugs in the treatment of pediatric bronchial pneumonia,and to provide reference for rational use of drugs in the clinic.METHODS:150 Pediatric cases of bronchial pneumonia in our hospital from Jul.2005 to Mar.2006 were randomly divided to 5 groups(n=30).Each group were given different antibacterial therpy.The hospitalization duration and medical costs were processed and analyzed using PEMS software under cured and discharge condition.RESULTS:Bactericide penicillin or cephalosporin combined with antibacterial drugs erythromycin or clindamycin would lower the antibacterial effect and aggravated economic burden of patients.Penicillin combined with cephalosporin is optimal,the cheapest and time-saving therapy for pediatric bronchial pneumonia.CONCLUSION:The application of drugs for pediatric bronchial pneumonia is reasonable basically.

Hepatitis C viral RNA in sera from 10 patients with post-transfusion hepatitis in Shanghai (China) were amplified By the nested PCR with primer sets deduced from the American prototype HCV RNA 5' -untranslated region. Eight of 10 cases (80%) were positive. And manipulations of PCR were simplified by combination of reverse transcription step and the first round PCR reaction. Our results indirectly proved that 5-untranslated region of HCV RNA of Shanghai showed a high degree of comservation and homology compared with isolates from some regions in the world.

Objective To explore the dose- and time-responses of BPCBG on the decorporation of uranium and its protective effects for uranium-induced kidney injury in rats. Methods Sprague-Dawley (SD) male rats were randomly divided into 4 -7 groups:normal control group,uranium poisoning group,different doses of BPCBG groups and DTPA-CaNa3 group. Rats in chelating agents-treated groups were either injected intramuscularly with 60,120 and 600 μmol/kg of BPCBG or 120 and 600 μmol/kg of DTPA-CaNa3 immediately after intraperitoneal injection of uranyl acetate dihydrate,or injected with 120 μmol/kg of BPCBG 0.5,2 h before or 0,0.5,1 and 2 h after injection of uranium. Uranium poisoning group rats were injected with normal saline after intraperitoneal injection of uranyl acetate dihydrate,and the normal control group rats were merely injected with normal saline. The uranium content in urine,kidney and femurs were detected 24 h after chelator injections by ICP-MS method.After injecting a dose of 500 μg uranyl acetate dihydrate,rats were injected with 600 μmol/kg of BPCBG or 1200 μmol/kg of DTPA-CaNa3. Histopathological changes in the kidney and serum creatinine and urea nitrogen were examined 48 h after chelator administration.Results Prompt injections of BPCBG resulted in 37％ -61％ ( t =2.22,4.43,5.80,P ＜ 0.05 ) increase in 24 h-urinary uranium excretion,and significantly decreased the levels of uranium in kidney and bone by 59％ -69％ (t=3.33,5-59,4-53,P＜0.01) and 14％ -58％ (t =2.15,8.70,9.10,P ＜ 0.05 ) respectively in a dose-dependent manner. BPCRG injection obviously reduced the severity of the uranium-induced histological alterations in the kidney,which was in parallel with the amelioration noted in serum indicators,serum creatinine and urea nitrogen,of uranium nephrotoxicity.Advanced 0.5 h or delayed 0.5 and 1 h administrations of BPCBG were effective in 24 h-urinary uranium excretion ( advanced 0.5 h:t =4.34,delayed 0.5 h:t =3.35,P ＜ 0.05 ),decreasing accumulation of kidney uranium ( t =5.75,7.74,5.87,P ＜ 0.05 ) and accumulation of hone uranium (t =6.43,5.222,2.60,P ＜0.05),but the efficacy decreased with the interval time between uranium and BPCBG injection. Although DTPA-CaNa3 markedly reduced uranium retention in kidney (120,600 μmol/kg,t =2.28,3.35,P ＜ 0.05 ),its efficacy in uranium removal was significantly lower than that of BPCBG,and it had no protective effects against uranium-induced nephrotoxicity.Conclusions BPCBG can effectively decorporate uranium from rats and protect against uranium-induced kidney injury of rats.

Objective Delve into the applied value of CDFI to diagnose deep vein thrombosis(DVT)in lower limbs.Methods Analyze the diagnosis of 65 chronic cases of DVT with a two-dimensional CDFI,and contrast it with the operation,X-ray angiography and clinical features.Results 36 acute cases of DVT;29 chronic cases of DVT;38 cases of lesion in left lower hmb(58.5%);21 in right lower limb(32.3%);and 6 in both lower limbs(9.2%).In the chronic cases,11 have formed collateral branch circulation.Conclusion CDFI has a safe and rapid effect on vein illness in lower limbs and can show the state of blood streams and the condition around the veins.It Can explain the unknown swollen in limbs.Realizing DVT in early stage has good value for its occurring,expanding and treating.

Objective To investigate the echocardiographic determination of uremic patients with myocardial weight and in the evaluation of cardiac function in patients with uremia heart the significance of the damage.Methods 70 cases of uremic patients and 30 normal physical were examined by routine echocardiography,cardiac measurements through the menu of uremic patients with myocardial weight and heart function.The patient group and the normal control group were compared.Results 70 patients with uremic echocardiography resuits of the analysis showed,respectively,12.8%and 84.3%existence of left ventricular systolic dysfunction and left ventricular diastolic dysfunction.left ventricular mass in patients with significant increase are significantly higher than those in healthy control group(P＜0.01).Conclusion Uremic patients left ventricular diastolic dysfunction and left ventricular hypertrophy most of echocardiography is the detection of cardiac damage in patients with uremia practical,sensitive,non-invasive examination will be able to clinical diagnosis and treatment provide guidance in the clinical widely used.

Objective To explore the Diagnostic value of real-time three-dimensional ultrasound for urethral vaginal fistulas.Methods 5 patients with urethral vaginal fistulas were checked using real-time three-dimensional ul-trasound ,respectively by the abdomen and the sonographic appearance of pudendal observation of female urethral vagi -nal interval sagittal and transverse ,sagittal and transverse section by measuring the size of the fistula ,and voiding trial or colored liquid test injection from urethral to confirm .Results 5 cases of urethra,vagina ultrasonography can dis-play and urethral vaginal interval throughout the sagittal plane and different levels of cross section ,urethral vaginal in-terval by low echo-band-low echo constitute the sandwichsign in the fistula showed partial loss ,local band echo in-terruption,urethral and vaginal local fusion ,voiding trial or from the urethra into the colored liquid test further con-firmed the fistula,fistula and verify the existence of fistula after the operation the size .Conclusion Real time three-dimensional echocardiography by urethral vaginal interval in the axial and sagittal plane ultrasound at different levels , combining with the history and voiding trial or injected with colored liquid test from the urethra ,can provide a new i-dea for diagnosis of urethral vaginal fistula .

Objective To observe the efficacy of Zhuang’s medicated thread moxibustion plus acupoint thread embedding in treating allergic rhinitis.Method By using random number table, 103 patients with allergic rhinitis were randomized into a treatment group (n=53) and a control group (n=50). The treatment group was intervened by Zhuang’s medicated thread moxibustion and acupoint thread embedding, while the control group was by acupoint thread embedding alone. The subjects were treated for 6 courses with a one-month follow-up. The therapeutic efficacies were compared between the two groups.Result The total effective rates were respectively 94.3% and 80.0% in the treatment group and control group.Conclusion Zhuang’s medicated thread moxibustion plus acupoint thread embedding has significant advantage in improving the symptoms of allergic rhinitis.

Anti-tumor necrosis factor-α(anti-TNF-α)agents have been widely used in the treatment of inflammatory bowel disease(IBD)in children.Anti-TNF-α therapy can effectively induce and maintain disease remission, promote intestinal mucosal healing, and prevent long-term end-stage organ damage and growth retardation in pediatric IBD patient.Anti-TNF-α agents can significantly impair the human immune function, which may increase the infection risk of IBD children, including the infection of bacteria, viruses, fungi and mycobacteria.This study summarizes the current published literature regarding infections in pediatric patients with IBD receiving anti-TNF-α therapies, which can help to improve the cognition of pediatric medical staff on opportunistic infection of pediatric IBD patients following anti-TNF-α treatment.