1.Clinical Research of the Treatment of Infantile Muscular Torticollis with the Primary Massages of Twining Manipulation with One Finger
International Journal of Traditional Chinese Medicine 2009;31(2):124-127
Objective To observe the clinical effects of treating infantile muscular torticollis with the primary massage therapy of twining manipulation with one finger and by the traditional massage therapy. Methods 300 cases were randomly recruited into a control group (141 cases) and a treatment group (159 cases). The treatment group was treated with primary massage of twining manipulation with one finger, while the control group was treated with conventional massage. Both groups were treated once daily. 20 min for each time, and 15 days constituted one therapeutic course. After 4 therapeutic courses, the changes of the shape and the size of the sternocleidomastoid muscle were detected by two-dimensional supersonic examination, the changes of the stream of blood of the sternocleidomastoid muscle was observed by the colored doppler supersonic observation, and assessed the overall curative effect combined with neck deflection degree and the activity. Results In the treatment group, 33 cases were healed, excellent therapeutic effects were seen in 72 cases, effectiveness were seen in 45 cases, 9 cases were inefficacy, and the total effective rate was 94.34%; In the control group, 9 cases were healed, excellent therapeutic effects were seen in 36 cases, effectiveness were seen in 75 cases, 21 cases were inefficacy, and the total effective rate was 85.11%. The result of the two groups showed a significant difference (P<0.05) .Conclusion Infants muscular torticollis mainly treated by twining manipulation with one finger showed a better result than conventional massage. It can effectively shorten the therapeutic time and avoid the Sequela due to the protraction of disease.
2.Research Progress of the Massage Therapy in Treating Infantile Muscular Torticollis
International Journal of Traditional Chinese Medicine 2009;31(1):82-84
Massage therapy is commonly used in the treatment of infantile muscular torticollis clinically.The massage therapy can reduce the therapeutic course effectively and prevent the occurrence of sequel due to long-term un-heating of the disease.This research provided many manipulative methods of massage in treating infantile muscular torticollis for clinical uses.
3.Research progress of treating osteoporosis with single Chinese medicine of tonifying kidney
Yixin KANG ; Jianchuan LI ; Guanglei LI
International Journal of Traditional Chinese Medicine 2010;32(4):362-365
In recent years, pharmacological researches of Chinese medicine found that single Chinese medicines of tonifying kidney, such as epimedium, psoralen, eucommia, dipsacus, cistanche, velvet, curculigo and cynomorium had very good effects of resisting osteoporosis, significantly improving the bone mineral density (BMD) and bone mineral content (BMC) , promoting hone formation, and preventing bone absorption. Based on the documentations from home and abroad, the overview had analyzed the current situation for providing new ideas and methods of osteoporosis prevention and treatment.
4.Research progress of treating Osteoporosis with single Chinese medicine of activating blood and dissolving stasis
Yixin KANG ; Shanjiang YU ; Youjian YU
International Journal of Traditional Chinese Medicine 2010;32(3):267-270
In recent years,pharmacological researches of Chinese medicine found that the single Chinese medicines of activating blood and dissolving stasis,such as Drynaria and Bidentata and Salvia and Panax notoginseng had very good effects of resisting osteoporosis,significantly improving bone mineral density(BMD)and bone mineral content(BMC),promoting bone formation,and preventing bone absorption.Based on the documentations from home and abroad,the overview had analyzed the current situation for providing new ideas and methods of osteoporosis prevention and treatment.
5.Research progress of single Chinese exterior-relieving medicine in the treatment of osteoporosis
Yixin KANG ; Guangyuan ZHANG ; Youjian YU
International Journal of Traditional Chinese Medicine 2010;32(2):180-184
In recent years, pharmacological researches of Chinese medicine have found that single Chinese exterior-relieving medicines such as Pueraria, Semen Sojae Praeparatum and Cimicifuga had very good anti-osteoporosis effect. They can significantly improve the bone mineral density (BMD) and bone mineral content(BMC), promote bone formation, and prevent bone absorption. Based on relative documents from home and abroad, this paper analyzed the current situation and provided new ideas and methods for prevention and treatment of osteoporosis.
6.Experimental research of treating osteoporosis with the method of kidney-tonifying and bone-strengthening massage therapy
Yixin KANG ; Daoquan WANG ; Yan LU ; Jing ZHANG
International Journal of Traditional Chinese Medicine 2011;33(12):1086-1089
Based on the kidney controlling bones of traditional Chinese medicine theory,this article researched the effects of treating osteoporosis with the method of kidney-tonifying and bone-strengthening massage therapy.Commonly used method of modeling included ovariectomized rat model of osteoporosis (OVX),senile rat model of osteoporosis and glucocorticoid induced rat model of osteoporosis (GIOP),kidney-tonifying and bone-strengthening massage therapy were applied on these models,and the rat bone mineral density (BMD) and biochemical marker of bone metabolism changes were observed.Confirmed by animals experiment,it was effective to repair a bone in all rat osteoporosis models with kidney-tonifying and bone-strengthening massage,which provided theoretical basis and methodological guidance for the use of kidney-tonifying and bone-strengthening massage therapy in the clinical treatment of osteoporosis.
8.Clinical research on hepatitis C virus infection in non-Hodgkin lymphoma patients
Yixin KANG ; Xiaoli SUN ; Qingsong YIN ; Yufu LI ; Yongping SONG
Journal of Leukemia & Lymphoma 2013;22(3):151-153
Objective To explore the correlation between non-Hodgkin lymphoma (NHL) and hepatitis C virus (HCV) infection.Methods HCV infection of 208 NHL patients was investigated from the Affiliated Tumor Hospital of Zhengzhou University.Patients with leukemia or other tumors,and healthy people were used as the control and were pair matched on age and gender.ELISA method was used to detect the HCV-antibody in serum.Results HCV-antibody positive rate in NHL patients [11.5 % (24/208)] was significantly higher than those in leukemia patients [3.8 % (8/208)] (x2 =8.667,P =0.003),patients with other tumors (6/208,2.9 %) (x2 =11.639,P =0.001) and healthy people [1.0 % (2/208)] (x2 =19.856,P =0.000).Conclusion HCV infection is related to NHL in Henan area.
9.Effect of SIRT1 gene silencing on radiosensitivity of diffuse large B-cell lymphoma cells
Yixin KANG ; Shegan GAO ; Yanzhen GUO ; Jun YAO ; Zhiye ZHANG ; Xiaohui GAO ; Dianbao ZHANG ; Shuangshuang GUO ; Lulin ZHANG
Chinese Journal of Radiation Oncology 2017;26(6):687-690
Objective To explore the effect of SIRT1 gene silencing on the radiosensitivity of diffuse large B-cell lymphoma (DLBCL) cells.Methods Immunohistochemistry was used to measure the protein expression of SIRT1 in DLBCL tissues.Western blot was used to measure the expression of SIRT1 in DLBCL cell lines (OCI-Ly3,SU-DHL-2,and SU-DHL-4) and the immortalized B cell line HMy2.CIR.After SU-DHL-4 cells were transfected with si-SIRT1 and si-NC using Lipofectamine 2000,the expression of SIRT1 was determined by Western blot.MTT assay and colony-forming assay were used to assess the cell growth and colony formation ability of SU-DHL-4 cells treated with radiation.The group t-test or univariate analysis of variance was used for comparison between groups.Results The expression rate of SIRT1 in DLBCL tissues was 72.6%(103/140),which was significantly higher than that in reactive lymphoid hyperplasia (RLH) tissues (26.5%,8/25)(P=0.001).The SIRT1 expression was significantly higher in DLBCL cells than in HMy2.CIR cells (P=0.020).After SIRT1 gene silencing by si-SIRT1,the expression of SIRT1 was significantly reduced in SU-DHL-4 cells (P=0.008).Besides,SIRT1 gene silencing significantly reduced the growth rate and colony formation ability of SU-DHL-4 cells treated with radiation (P=0.030).Conclusions SIRT1 gene silencing enhances the radiosensitivity of DLBCL cells,providing a novel target for the radiotherapy of DLBCL.
10.Dynamic changes in Th17/Treg balance among children with seasonal allergic rhinitis
Qing MIAO ; Xi CHEN ; Yixin REN ; Yongge LIU ; Yan WANG ; Wei XU ; Zhen LI ; Hui GUAN ; Huijie HUANG ; Xiaoling HOU ; Kang ZHU ; Qi GAO ; Yaru WANG ; Li XIANG
Chinese Journal of Microbiology and Immunology 2017;37(5):355-360
Objective To investigate the levels and significance of Th17 cells and regulatory T cells (Treg) in peripheral blood of children with allergic rhinitis during pollen and non-pollen seasons.Methods Thirteen children with hay fever, 10 children with house dust mite(HDM)-allergic asthma and 10 healthy children were recruited into this study.Percentages of Th17 and Treg cells were detected by flow cytometry.Levels of IL-17, IL-10 and TGF-β in cell culture supernatants were measured by ELISA.Results (1) The percentages of Th17 cells in children with allergic rhinitis [(3.4±2.4)%] were significantly higher than those in HDM-allergic asthmatics [(2.1±1.6)%] and those in healthy children [(0.5±0.3)%] during pollen season (both P<0.05).The levels of Treg cells in allergic rhinitis group [(2.1±1.3)%] and in HDM-allergic asthma group [(3.6±1.9)%] were significantly lower than those in healthy control group [(5.5±2.8)%] (both P<0.05).The levels of Th17 cells [(3.0±1.9)% vs (3.4±2.4)%, P<0.05] and ratios of Th17/Treg cells [(1.4±1.0)% vs (1.7±1.5)%, P<0.05] in children with allergic rhinitis were significantly decreased during non-pollen season as compared with those during pollen season, but the levels of Treg cells were up-regulated [(2.4±1.6)% vs (2.1±1.3)%, P<0.05].(2) Correlation analysis revealed that the ratios of Th17/Treg cells were positively correlated with the concentrations of FeNO (fractional concentration of exhaled NO) (r=0.321, P<0.05) and the counts of circulating eosinophils (r=0.198, P<0.05) in children with allergic rhinitis during pollen season.Conclusion The imbalanced Th17 and Treg cells in children with allergic rhinitis during pollen season might play a vital role in the regulation of allergic airway inflammation.