1.Performance and Application of Decompression and Low Coated Non-polar Liquid Phases in Gas Chromatographic Column
Chinese Journal of Analytical Chemistry 2001;29(5):549-551
In this paper,performance of decompression and low coated gas chromatographic column of non-polar liquid phases is described. Chromatographic parameters of a column packed with 0.5% OV-101 on glazing support (φ0.18~0.25mm) 302 was studied for C、C7、C8、C9 n-alkanes samples. The results showed that the column pressure 0.068 MPa was best,the column temperature for n-octane could be decreased to 52°C,column efficiency was four time as high as ordinary pressure detection.
2.Promote community nurses scientific research capacity of practical research
Chinese Journal of Medical Science Research Management 2015;28(5):405-408
Objective Explore the effective way to improve the research capacity of community nurses and to enhance their knowledge of scientific research.Methods Questionnaires were given to 10 community health service centers in Shanghai Qingpu District and 346 community nurses, who represent 93.51% of the total community nurses, the results have been statistically analyzed which involves timely intervention.Results The effective ways to improve the research capacity of community nurses are listed as follows in proper order: organize scientific workshops;increase the support for nursing research;build a platform for access to literature;strengthen community care research tracking guidance.Conclusions Effective ways and means should be applied when carrying out community nursing researches in order to accelerate the scientific research ability of community nurses.
3.The risk stratification of patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention
Chinese Journal of Interventional Cardiology 2003;0(05):-
Objective To evaluate the prognosis capacity of the Primary Angioplasty in Myocardial Infarction (PAMI) risk score for 6 months mortality in the clinical patients with ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention (PCI), in addition to asses the incremental value of EF and multivessel disease for risk stratification. Methods Six clinical variables and their relative value of score derived from PAMI risk scoring system were used to determine individual's risk score. The patients with STEMI were evaluated during the in-hospital period and followed-up for a mean of (10.34?3.24) months for mortality. The p values were calculated using a Kruskal-Wallis H test for categorical variables when appropriate; otherwise Independent-samples test was used. Logistic regression examined the discriminant accuracy of the PAMI risk score to predict death and assessed the incremental value of the EF and multivessel disease. Results A 88.8% of patients (183 patients) finished the follow up of 6 months. The overall in-hospital mortality rate was 4.4%, 30-day mortality rate was 6% and 6 months mortality rate was 9.3%. Eighty-eight patients scored 0-2 points, 54 patients scored 3-5 points, 17 patients scored 6-8 points and 24 patients scored ≥9 points. The 6 months mortality were 1.1%,3.7%, 17.6% and 41.7% respectively. Logistic regression analysis indicated that multivessel disease is a risk factor (OR 10.189) and EF is a protected factor (OR 0.849) for 6 months mortality after PCI. Multivessel disease and EF provided incremental information over that provided by the PAMI risk score. Conclusion The PAMI risk score can be applied in early stage after PCI for mortality risk assessment for patients with STEMI. EF and multivessel disease also convey important prognostic information and should be included in risk stratification after STEMI.
4.Study on the short version of the BFS mood scale and its reliability and validity
Jinjin GAO ; Fei ZI ; Yiwen CHEN
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(4):373-375
ObjectiveTo provide a brief scale of mood measurement with satisfactory reliability and validity.MethodsThe 40-item BFS was abbreviated to a short-vcrsioncd BFS by item analysis.282 adult participants were surveyed by the brief BFS and NEO-FFI while NEO-FFI was taken as a criterion instrument.Reliability and validity of brief BFS were examined.ResultsThe brief BFS had 18 items including six dimensions ( activity,cheer,calmness,indignation,stir and depression),and the cronbach's α were 0.87,0.75,0.85,0.86,0.84 and 0.86 respectively and the retest reliability( r value) were 0.67,0.57,0.61,0.62,0.75 and 0.69 respectively.All the key fit indices of confirmatory factor analysis (CFA) of brief BFS were above 0.90.Besides,NEO-FFI had significant correlation with brief BFS.ConclusionThe brief BFS has satisfactory reliability and validity.
5.Compound clindamycin liniment in treatment of acne vulgaris
Yiwen LIU ; Ping LU ; Meijuan CHEN
Chinese Journal of New Drugs and Clinical Remedies 2001;20(2):127-128
AIM: To observe the effect of compound clindamycin liniment on acne vulgaris. METHODS: A multi-centre, open-label trial of compound clindamycin liniment in treating acne vulgaris. One hundred and fifty-three patients used compound clindamycin liniment on face three times per day for 4 wk. RESULTS: The total excellent response rate was 83.0%. The total effect rate on pustule and papule was 96.1% and 80.7% respectively. The adverse reaction rate was 1.9%. CONCLUSION: Compound clindamycin liniment is an effective and safe drug in the treatment of acne vulgaris.
6.Conduct disorder of 669 secondary vocational students and relationship to learning burnout, self-rated health
Juntao ZHANG ; Yiwen CHEN ; Weidong WU
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(4):346-348
Objective To explore conduct disorder tendency and it's influence factors on secondary school students. Methods 669 students of grade 1 in Dezhou Vocational and Technical College were investigated by Conduct Disorder Tendency Questionnaire, Revised Version of MBI-SS and SRHMS Version1.0. Results The secondary vocational school students' scores on violation tendency, addiction tendency and aggression tendency were 11.51±4.08,5.90±2.68 and 6.68±2.63,and were significant different from vocational college students or high school students(addiction tendency:F(2, 1578)=7.48,P =0.001;aggression tendency:F(2, 1579)=24.40,P <0.001). There existed great capable difference of conduct disorder according to genders ( t(643)>3.85,P <0.001).Conduct disorder tendency of secondary vocational students' was positive correlated with their learning burnout (Pearson correlation coefficient was between 0.16 and 0.52 for each pair), but negative correlated with mental health(Pearson correlation coefficient was between -0.13 and -0.27 for each pair). The linear regression showed that some dimensions of learning burnout and self-rated mental health predicted students' conduct disorder tendency. Conclusion Conduct disorder tendency of secondary vocational students is affected by their learning burnout and mental health.
7.Progress in diagnosis and treatment of mantle cell lymphoma
Gege CHEN ; Jumei SHI ; Yiwen ZHANG
Journal of Leukemia & Lymphoma 2016;25(10):637-640
Mantle cell lymphoma (MCL) is a group of highly aggressive non-Hodgkin lymphoma (NHL) in small B-cell lymphoma, accounting for 6 % of NHL incidence. MCL is characterized with its concealed onset, strong aggression, high malignancy and poor prognosis. Therefore, more attention should be paid to the diagnosis and differential diagnosis of MCL in clinic. Recently, diagnostic models of molecular pathology, researches on cyclin D1 protein negative MCL, staging prognosis and stratification treatment of MCL are worthy of attention.
8.Association of serum levels of matrix metalloproteinases and their tissue inhibitors with mortality in patients with malignant middle cerebral artery infarction
Yiwen CHEN ; Geng LI ; Lijun LU
Journal of Chinese Physician 2016;18(11):1671-1673
Objective To investigate the relationship between serum levels of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMP) and the mortality in patients with malignant middle cerebral artery infarction.Methods A total of 74 patients with malignant middle cerebral artery infarction (MMCAI) was assigned to research group,74 healthy volunteers were recruited to serve as healthy controls,and 242 patients with other cerebral infarction were recruited to serve as case controls.Quality-of-life questionnaire and clinical examination were used to collect the information of participants.Endpoint was 30-day mortality.Results The research group showed higher serum levels of MMP-9,MMP-10,and TIMP-1 relative to the case control group,and the case control group showed higher serum levels of MMP-9,MMP-10,and TIMP-1 relative to the healthy control group (P < 0.05).Compared to survivor ones,non-surviving MMCAI patients showed lower Glasgow Coma Scale score (P < 0.05),higher serum levels of tumor necrosis factorα (TNF-α),MMP-9,MMP-10,and TIMP-1 (P < 0.05).Multiple logistic regression analysis showed that serum levels of TNF-α,MMP-9,MMP-10,and TIMP-1 were associated with 30-day mortality,and the OR were 1.09,1.18,1.13,and 1.32,respectively.Conclusions Serum levels of MMP-9,MMP-10,and TIMP-1 levels in MMCAI patients were associated with mortality,and could be used as an auxiliary index of mortality in MMCAI patients.
9.EFFECTS OF LUTEOLIN ON H_2O_2 RELEASE OF PERITONEAL MACROPHAGES IN RAT
Yiwen ZHENG ; Donglai MA ; Minzhu CHEN
Chinese Pharmacological Bulletin 1987;0(01):-
Using the fluorescence method, the effect of Luteolin ( Lut) on H2O2 release of peritoneal macrophages(M(?)s) in rat was studied. The results showed that H2O2 release of peritoneal M(?)s stimulated by op-sonized Zymosan was reduced by in vitro treatment of Lut. The inhibitory effect of Lut is in a concentration-dependent manner over the range of 4 ? 10-7-10-5mol/L. When M(?)s was cultivated with Lut for 4 h, the inhibitory effect of Lut was the most obvious.
10.Determination of Tin in Air by Microwave Digestion-HG-AFS
Feirong ZHAO ; Qian PENG ; Yiwen CHEN
Journal of Environment and Health 1989;0(06):-
Objective To develop a method for determination of tin in the air of workplace by microwave digestion-HG-AFS. Methods The air samples were collected and the concentration of tin was determined by microwave digestion-HG-AFS and the parameters of atomic fluorescence spectrometry were studied. Results In the optimum condition, the detection limit of tin was 0.3 ?g /L, the lowest detected concentration of tin in the samples was 0.000 1 mg/m3 (based on 75 L air sample), the RSD was 2.7%-3.5%, the rate of recovery was in the range of 96.5%-104.7%. Conclusion The method is rapid, convenient, accurate, sensitive and suitable for determination of tin in the air of workplace.