OBJECTIVETo examine the hypothesis that functional appliances enhance mandibular growth in the treatment of skeletal Class II malocclusion.

METHODSA literature search was performed in electronic databases according key words "skeletal Class II malocclusion" , and full texts of selected articles were collected by hand-made method. The data were extracted from the articles. The quality of the trials was evaluated and meta-analysis method was used to analyze the data through RevMan 4.2.

RESULTS19 articles could be qualified for the final analysis. Those indices including SNB (Activator, Twin-block, Herbst group), Go-Gn, Co-Pg, Co-Gn, Co-Go, demonstrated significant effect of functional appliances on mandibular growth in comparing with those of untreated control group. There were no significant differences between the two groups for the indicies of SNB (Fränkel-II) and Go-Me.

CONCLUSIONFunctional appliances can enhance mandibular growth in treatment of skeletal Class II malocclusion. This mainly dues to the growth of the ramus instead of changes of mandibular body length.

Cephalometry ; Humans ; Malocclusion ; Malocclusion, Angle Class II ; Mandible ; Orthodontic Appliances, Functional

Objective:To explore the association between dietary patterns and the incidence of type 2 diabetes mellitus(T2DM), so as to provide insights for the prevention and management of T2DM.Methods:Participants were recruited from the " The Tianjin Chronic Inflammation and Health Cohort Study(TCLSIH)" cohort study from 2013 to 2018, who had completed the modified semiquantitative food frequency questionnaire(FFQ) and blood glucose testing( n=26 425), free of cardiovascular disease, cancer, or diabetes at baseline. The relevant information collected includes food frequency, blood glucose concentration, and other confounding factors. In this study, the correlation between dietary patterns and T2DM was tested using Cox proportional risk regression model, and the gender stratification analysis and body mass index stratification analysis of different gender groups were carried out. All statistical analysis was performed using SAS 9.3 software. Results:The age of all participants was (41.0±11.5)years, and the cumulative incidence was 3.84% for T2DM. The cumulative incidence of T2DM in male population was 5.29%, while that in female population was 2.16%. There were significant differences in the incidence of T2DM among different genders( P <0.001). The multivariable-adjusted hazard ratios( HR) and corresponding 95% CI of T2DM across the plant-based dietary pattern score were 1.09(95% CI 0.91-1.31), 0.80(95% CI 0.66-0.97), and 0.76(95% CI 0.62-0.94; Ptrend =0.010). Moreover, no statistically significant differences were observed between animal and traditional northern Chinese diets with the incidence of T2DM. Conclusions:The plant-based dietary patterns were associated with substantially lower risk of developing T2DM, and there were no significant association between animal and traditional northern Chinese dietary patterns with T2DM. Plant-based dietary patterns characterized by a variety of fruit, leeks, onions, seaweed may be beneficial to the prevention and control of T2DM.