Objective To evaluate the effect of local arterial infusion (LAI) of medicine on the treatment of servere acute pancreatitis(SAP). Methods The clinical data of 85 cases of SAP were retrospectively analyzed, and divided into three groups according to the admitted time:Group A. 42 cases admitted from February 1982 to December 1993,treated mainly by operation. Group B. 23 cases, admitted January 1994 to Auguest 1996, treated mainly by non operation. Group C. 20 cases, from September 1996 to Auguest 2000. treated mainly by LAI. Results The secondary infection rate in group A, B and C were 47%(20/42),26%(6/23) and 10%(2/20) respectively. The mortality in group A ,B and C were 36%(15/42),22%(5/23) and 5%(1/20),respectively. The difference in the secondary infection rate and mortality between group A , B and group C showed obvious significance (P

Objective:To construct the whole-process intelligent management system for preventing PICC-related bloodstream infections and explore its effect in preventing PICC-related bloodstream infections.Methods:From January 2021 to December 2022, patients with PICC admitted to Wenzhou People' s Hospital were selected as the research subject, the patients from January to December 2021 were divided into the control groups, the patients from January to December 2022 were divided into the observation group. The whole-process intelligent management system for preventing PICC-related bloodstream infections was constructed and applied with artificial intelligence, this study compared the incidence of PICC-related bloodstream infections and the implementation rate of PICC whole-process bundled management projects before and after system application.Results:The incidence of PICC-related bloodstream infections in the control group was 0.55‰ (14/25 674), while the incidence in the observation group was 0.20‰ (5/25 226), with a statistically significant difference (χ 2=4.110, P<0.05). The implementation rates of PICC whole-process bundled management projects in the control group and observation group were 74.04% (2 319/3 132) and 92.11% (2 885/3 132), respectively, with a statistically significant difference (χ 2=363.782, P<0.01) . Conclusions:The whole-process intelligent management system for preventing PICC-related bloodstream infections constructed optimizes the prevention and treatment process of PICC-related bloodstream infections, effectively ensures the implementation of nursing interventions and monitoring measures, and reduces the incidence of PICC-related bloodstream infections.

Objective To study laparoscopic microwave ablation (LWMA) in treating colorectal cancer liver metastases,and to evaluate its local efficacy and the factors influencing long-term survival.Methods A retrospective study was conducted on 24 patients with hepatic metastases after radical surgery of colorectal cancerin.These patients were treated with LWMA in Wenzhou People's Hospital from April 2012 to April 2017.The complete ablation,major complication,overall survival and disease-free survival rates were determined,and the factors influencing survival were analyzed.Results 71 tumor lesions in 24 patients were treated with LWMA.After the initial LWMA,complete tumor ablation was achieved in 70 lesions (98.6％).There were no serious adverse reactions and perioperative deaths.Conclusions LWMA had good short-term and long-term results.There were no serious adverse results.LWMA is an efficacious and safe treatment for patients with CRLM.

Objective: To investigate the effect of anastomotic reinforcing sutures on the incidence of anastomotic leakage after laparoscopic radical resection of rectal cancer. Methods: In this study, 300 patients diagnosed with rectal cancer, scheduled to undergo laparoscopic anterior resection at the Department of Gastrointestinal Surgery of Anhui Provincial Hospital, between September 2014 and December 2016, were prospectively enrolled. Patients were randomly assigned to undergo laparoscopic rectal resection with (reinforcing group, n = 150) or without (control group, n = 150) anastomotic reinforcing sutures. The laparoscopic total mesorectal excision was followed for all patients. In the reinforcing group, 4-0 absorbable sutures were used to reinforce the 2-4 needles used for the 2 cross-cutting lines that formed the stapler. Concurrent obstructions; the need for hemorrhagic emergency surgery, preventive ileostomy, Hartmann operation, abdominoperineal resection, or open surgery; and the presence of unresectable cancer were all reasons for excluding patients from the study. Univariate and multivariate analyses were performed on the clinical data collected for the two groups. According to the multivariate analysis results, patients were further divided into high-risk (≥ 2 high risk factors) and low-risk (≤1 high risk factor) groups, and were stratified to analyze the relationship between reinforcing suture use and the incidence of anastomotic leakage. This trial, approved by the Ethics Committee of Anhui Provincial Hospital, was registered as NCT02830633. Results: A total of 291 patients were included in the study, namely 145 in the reinforcing group and 146 in the control group. There were no significant differences between the two groups with respect to their general data or intra-operative conditions (all P > 0.05) . The overall incidence of anastomotic leakage was 7.6% (22/291) ; 3.4% (5/145) in the reinforcing group and 11.6% (17/146) in the control group (χ² = 6.992, P = 0.008) . Multivariate analyses showed that the lack of reinforcing sutures was an independent risk factor for anastomotic leakage (OR = 2.75; 95%CI, 1.72-5.48; P = 0.014) . Other independent risk factors included NRS2002 score ≥ 3 points, tumor diameter ≥ 4 cm, and tumor to anal margin distance < 5 cm. There were 80 patients in the high-risk group and 211 in the low-risk group, based on the aforementioned 3 risk factors. The incidence of anastomotic leakage was 27.1% (13/48) among the control patients in the high-risk group, but only 6.2% (2/32) among high-risk patients receiving reinforcing anastomotic sutures (χ² = 5.470, P = 0.019) . In the low-risk group, the incidence of anastomotic leakage was 2.7% (3/113) among patients receiving reinforcing anastomotic sutures, and 4.1% (4/98) among those not receiving reinforcing sutures. No significant difference was observed (χ² = 0.333, P = 0.564) . Conclusion Anastomotic reinforcing sutures for the prevention of anastomotic leakage after laparoscopic radical resection of rectal cancer is convenient and effective, particularly for patients with multiple risk factors.

As an important new Chinese medicine international culture promotion platform,Overseas Chinese Medicine Center (OCMC) should seize the opportunity of the "Belt and Road" Initiatives to be the main force and national team of transmitting Chinese medicine overseas.Through the research and practice of OCMC expanding Chinese medicine territory,the author adopted "Chinese medicine + " mind in four directions (i.e.,breaking a passage by characteristic traditional Chinese medicine treatment,developing characteristic Chinese medicine education,enhancing Chinese medicine talent localization,seeking high-level international cooperation of scientific research,and etc.) to impel OCMC spreading Chinese medicine culture to the world.

Objective To investigate the application effect of diversified management models for bowel preparation in colonoscopic examination.Methods A total of 100 inpatients with colonoscopic examination in the gastroenterology department of this hospital from October 2021 to March 2022 were selected and divided into the control group and observation group by adopting the random number table method,50 cases in each group.The control group was given the routine nursing and the observation group implemented the diversified management model nursing.The Boston bowel preparation scale(BBPS)score,intestinal preparation qualifi-cation rate,awareness of intestinal tract preparation knowledge and patients satisfaction on the nursing service were compared between the two groups.Results The BBPS score in the observation group was(7.10±0.99)points,which was significantly higher than(6.08±1.00)points in the control group,and the difference was statistically significant(t=5.095,P＜0.001).The intestinal preparation qualification rate in the observation group was also significantly higher than that in the control group[92％(46/50)vs.76％(38/50)]and the difference was statistically significant(x2=5.556,P=0.018).The awareness rate of intestinal tract prepara-tion knowledge and nursing service satisfaction score in the observation group were higher than those in the control group(P＜0.05).Conclusion Implementing the diversified management model can effectively in-crease the cleanliness of intestinal tract preparation,improve the quality of intestinal tract preparation and pa-tients satisfaction on the nursing service and is conducive to improve the diagnosis and treatment effects of the patients.

Based on the empirical study in Britain,this paper revealed several problems in the cross-cultural communication of traditional Chinese medicine (TCM):the obstacles are still immense,the system is not complete,the tools are simple,the communication capacity is limited,and the "de-Sinofication" is obvious.The proposals are made as that,applying the concepts of communication and multi-disciplines,accomplishing the system to run as a huge systematic project,creating more means and increasing the capability of communication,conducting the cross-cultural communication training,cultivating talented people,developing domestic TCM to support the abroad TCM,operating as government-leaded projects to enhance national cultural soft power,contesting for supremacy and intellectual property rights in the worldwide TCM areas.