1.Surgical treatment and research progress of pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries
International Journal of Pediatrics 2011;38(4):404-407
Pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries is a rare kind of congenital heart disease. Nowadays, staged surgical treatment has been recognized by more and more surgeons with the surgical treatment of the disease continuing to progress and a deeper understanding of surgical treatment.
2.The effect of self-efficacy-oriented nursing intervention on postoperative quality of life of lung tumor patients
Jie YANG ; Yinyu GU ; Shuxia LI ; Yueyan HUANG ; Lijing ZHANG ; Zhijun XING
The Journal of Practical Medicine 2014;(18):2997-3000
Objective To investigate the effects of self-efficacy-oriented nursing intervention on postoperative quality of life of lung tumor patients. Methods Ninety patients with lung tumors undergoing chest surgery in our hospital from March 2010 to March 2012 , involved in the study. The nursing data were retrospectively analyzed for investigation of the nursing strategies. The patients were randomized into two group with random digits table in equal number: The control group received routine nursing and the intervention group with self-efficacy-oriented nursing intervention beside routine nursing care. 3 months after nursing intervention , the two groups were compared by Self-rating Depression Scale (SDS) and Self-rating Anxiety Scale (SAS) in terms of quality of life and psychological state. Results The scores of the intervention group by SDS and SAS were both significantly higher than those of the control group (P < 0.05). The scores of the intervention group on self efficacy and quality of life were significantly higher than those of the control (P < 0.05). Conclusion The self-efficacy-oriented nursing intervention applied in the postoperative nursing care to lung cancer patients can significantly improve the postoperative symptoms and psychological status. It can also improve their self efficacy and then enhance their quality of life.
3.Evaluation of multiparametric MRI in diagnosing early prostate cancer:a study based on PI-RADS version 2
Yongsheng ZHANG ; Huan YANG ; Youjun CAO ; Yinyu WANG ; Zhitian ZHANG ; Yinfeng MA ; Zaiqiu ZHAO ; Feng CUI
Journal of Practical Radiology 2017;33(7):1052-1055,1083
Objective To investigate the diagnostic value of multiparametric MRI in early prostate cancer(PCa) based on PI-RADS version 2.Methods 27 surgically-proved early PCa patients were collected in this retrospective study.T2WI,DWI and DCE were evaluated by two blinded radiologists.By 12 sub-region classification method the possibility of the presence of cancer at each sub-region was scored according to the PI-RADS V2.The receiver operating characteristic (ROC) curve was used to analyze the diagnosic efficacy of the following 4 protocols:T2WI alone(protocol 1),T2WI+DWI(protocol 2),T2WI+DCE(protocol 3),T2WI+DWI+DCE(protocol 4).The sensitivity,specificity and accuracy for each protocol were calculated.The average scores of cancerous sub-regions and non-cancerous sub-regions were calculated and the independent sample t test was used to compare the four protocols.Results 324 sub-regions were analyzed in 27 early PCa patients and then divided into 119 cancerous sub-regions and 205 non-cancerous sub-regions,including 64 peripheral zone cancerous sub-regions and transition zone cancerous sub-regions.In protocol 1-4, the average scores of cancerous sub-regions in orderwere 3.13±1.19,3.27±1.15,3.28±1.23, 3.33±1.16,respectively.Non-cancerous sub-regions's scores in order were 1.98±0.90,1.91±0.91, 2.03±0.99,1.94±0.96 respectively and there were significant differences among each protocol (P<0.05).The area under the ROC curve of the 4 protocols for region-based analysis were displayed in descending order: protocol 4 (0.819), protocol 2 (0.810), protocol 3 (0.772), protocol 1 (0.765) and there were no significant differences between any two protocols (P>0.05).In four protocols, the sensitivity in order were 45.40%, 56.30%, 59.70%, 61.34%, while the specificity in order were 95.10%, 96.10%, 89.80%, 96.60%, and the accuracy in order were 76.85%, 81.48%, 78.70%, 83.65%.Conclusion Multiparametric MRI can improve the diagnostic accuracy for the detection of early PCa, and T2WI+DWI+DCE is with the highest value.The PI-RADS V2 system is a better semi quantitative method for evaluation of early PCa.
4.Investigation and analysis of social support of clinical nurses in second-level hospitals in remote areas of Tibet
Ting CHEN ; Yinyu YANG ; Li QIAO ; Li LIU ; Jing WU ; Rong QIAO
Chinese Journal of Practical Nursing 2017;33(32):2546-2549
Objective To investigate the social support of clinical nurses in second-level hospitals in remote areas of Tibet, and to explore the influencing factors, so as to provide the basis for nursing managers to develop targeted interventions. Methods A total of 212 nurses were selected by convenient holistic sampling method and investigated by self-designed questionnaire and social support rating scale. Results The total score of social support of clinical nurses was (30.72 ± 6.78) points. The main influencing factors of social support were educational background(F=4.602),ages(F=2.694),working years (F=2.387), budgeted posts(t=2.391), income(F=3.112) and marital status (F=2.636). Difference was statistically significant(P<0.05). Conclusions The social support of clinical nurses in second-level hospitals in remote areas of Tibet is low. It is important to establish a relatively perfect social support system according to the difference of nurses working conditions and geographical to improve their work enthusiasm and satisfaction rate.
5.Clinical study on surgical repair of severe ALCAPA in infants and children
Jinghao ZHENG ; Wei ZHANG ; Xiaomin HE ; Yujie LIU ; Yinyu YANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2019;35(3):140-144
Objective To discuss the surgical treatment of anomalous origin of the left coronary artery from the pulmonary artery(ALCAPA) and the risk factors of postoperative recovery in infants and children.Methods A retrospective review of all patients who underwent surgical treatment of ALCAPA in Shanghai Children Medical Center(2003.1-2018.1) was conducted.Patients were divided into early surgery group (2003.1-2012.12) and late surgery group (2013.1-2018.1) according to the operation time,a preoperative left ventricular ejection fraction(LVEF) <0.35 was defined as severe group and LVEF≥0.35 as the control group in both surgery group.Meantime,and the clinical data among the groups were analyzed and compared.Results 102 patients were included in our study.According to the operation time and preoperative LVEF grouping:10 cases in the early severe group,early death in 4 cases(40%);28 cases in the early control group,and 3 cases died(10.7%)in hospital.Preoperative LVEF(0.29 ± 0.06 vs.0.53 ± 0.12),surgical age [(8.0 ± 7.9) months vs.(23.3 ± 27.7)months],and cardiopulmonary bypass time [(131.1 ± 39.6) min vs.(103.8 ± 29.8) min] were statistically different between the early two groups.The results of the late surgery had been improved:24 cases in the late severe group,4 cases died in hospital(16.7%);40 cases in the late control group,and early death in 2 cases (5%).In the late surgery groups,there was a statistically significant difference in preoperative LVEF(0.28 ±0.05 vs.0.59 ±0.12),left ventricular end-diastolic diameter(LVDD) Z-score(3.09 ±1.16 vs.2.11 ±0.95),and surgical age [(5.3 ±3.0) months vs.(24.8 ±30.5)months],clamping time [(67.1 ± 15.5) min vs.(82.7 ± 28.4) min].In the severe group,there was no significant difference in preoperative clinical data between early and late patients,and the early mortality decreased from 40% in the early period to 16.7% in the late period.In this study,13 cases(38.2%) of children with severe ALCAPA underwent mechanical circulation support(MCS).One patient died during MCS support and 2 died after weaning.Conclusion The early mortality severe ALCAPA remains high,which may be related to severe cardiac ischemia,left ventricular enlargement and age at surgical time.The modify of surgery technology and the use of MCS in the early clinical stage can improve the early survival rate.
6.Short term left ventricular assistive device use in postoperative pediatric patients with congenital heart disease
Wei ZHANG ; Yinyu YANG ; Haibo ZHANG ; Jinghao ZHENG ; Wei WANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2018;34(7):398-402
Objective To discuss the methods and experience of using short term left ventricular assist devices (LVADs) in patients after congenital heart disease(CHD) corrective surgery.Methods This study included 17 postoperative cases using short term LVAD support.The device used was a Maquet Rotaflow system, and the clinical patient data was collected and eval-uated retrospectively.Results The 17 patients were divided into two groups by the clinical outcome as follows: 6 cases in the early death group(Group D) and 11 cases in the survival group(Group S).The pre-support time[(9.00 ±9.95)h vs. (23.83 ±13.23)h, P=0.042]and the lactate level values[(4.01 ±2.15)mmol/L vs.(9.30 ±4.90)mmol/L, P=0.045] were significantly lower and more favorable in Group S.Patients in Group S also received a longer support time than patients in Group D.Conclusion Using the Maquet Rotaflow system is generally safe and efficient, when used as a short term LVAD in postoperative pediatric patients.The selection of patients, the timing of support, and reasonable management were the keys to patient survival.