Given that current axial flow blood pumps have certain structural defects,resulting in poor performance and inferior blood compatibility,an integrated axial flow blood pump is developed,and its geometry is optimized using computational fluid dynamics method.The study also investigates the effects of different operational parameters on the performance of the blood pump and compares with experimental data to determine the optimal conditions.Additionally,the flow patterns of the blood pump are comprehensively analyzed for further revealing the internal flow phenomena,and the behavior of red blood cells in the blood flow and their response to shear stress are simulated using discrete phase model to evaluate the blood compatibility of the blood pump.The study shows that the novel blood pump performed well in terms of head.Under the optimal condition with a rotational speed of 9 000 r/min and a flow rate of 6.24 L/min,the blood pump improves the head by 16%as compared with the original structure,and reaches 25%efficiency,which can meet the physiological needs of most people.The pressure gradient and velocity gradient in most areas within the blood pump are smooth,and the internal flow patterns are generally stable,effectively avoiding the occurrence of hemolysis.The optimized blood pump can ensure high-level performance and favorable flow field characteristics while maintaining superior blood compatibility,which provides important reference for the structural optimization of axial flow blood pumps.