1.Investigate the scientific research ability and training needs of the 62 new posts of medical undergraduates
Shuyun LIU ; Shuai WEI ; Yinlin ZHENG
Chinese Journal of Medical Science Research Management 2014;27(1):77-79
Objective To investigate the scientific research ability and training needs of the new posts of medical undergraduates for better training them.Methods A total of 62 new posts of medical undergraduates from a level-two general hospital in China were recruited by questionnaire survey.Resuits the scientific research ability of the new posts of medical undergraduates is poor,so it is very necessary for their in-service training,93.5~ of them have interest in scientific research and hope to get the training,especially want to take part in the practical activity.Conclusions It is not better that the scientific research ability of the new posts of medical undergraduates,so as early as possible to give the scientific research skill training to them.
2.Research on the construction and operation mechanism of the research platform of the county medical institutions in the construction of the medical association
Shuyun LIU ; Jun LIU ; Mengsha QI ; Yinlin ZHENG
Chinese Journal of Medical Science Research Management 2018;31(5):383-386,399
Objective How to make good use of the construction opportunity of the medical association to integrate resources,build scientific research platform and establish practical operation mechanism,to improve the technology innovation ability of district county-level hospitals.Methods Through literature analysis and empirical study,this paper discusses the feasibility and operation mechanism of the construction of research platform in district county-level hospitals.Results The research platform can be built with the help of medical association construction.The operation mechanism can effectively improve the research level of district county-level hospitals,by taking the chance of discipline construction,implementing the institutional mechanism for rewards and punishment.Conclusions With the help of superior medical experts,two-way referral,academic lectures and other activities,advanced scientific culture idea was spread;The training of scientific research personnel,resource integration,and project cooperation increased opportunities.All of this to set up a new platform for district county-level hospitals to promote their scientific and technological innovation abilities.By taking the chance of discipline construction,clarified target responsibility,to carry out the rewards and punishment system and the implementation of the scientific and technological innovation incentive mechanism,can force them to actively promote the ability of scientific and technological innovation,actively carry out scientific research and improve the level of business.
3.Protective effects of Naomaili granules on cerebral ischemia-reperfusion in rats and its mechanism
Yi REN ; Mei SU ; Jing ZHENG ; Yinlin QIN ; Tao CHEN ; Hui JI
Journal of China Pharmaceutical University 2015;46(1):100-104
The objective of the study was to determine the potential effects of Naomaili granules on rats subjected to ischemia and reperfusion. With the exception of animals in sham group, all animals in treatment groups were subjected to ischemia and reperfusion by middle cerebral artery occlusion(MCAO)with thread technique. The ability of anti-cerebral ischemia, relieving cerebral edema and antioxidation was evaluated by the measurement of neurological deficit score, ratios of infarction area, brain water content, histopathological score and biochemical indexes related to oxidative stress in brain tissue. Significantly reduction of infarction area, histopathological score, contents of H2O2 and MDA were observed at 6 g/kg and 3 g/kg Naomaili granules compared to animals in the model group; the capacity of inhibition of superoxide anion radical(O-·2)and hydroxyl radial( ·OH)were also found to have increased. Additionally, Naomaili granules(6 g/kg)improved neurological function, reduced brain water content, and increased the level of GSH, GSH-Px and SOD compared with model group. The result suggested that Naomaili granules exhibited obvious protection against cerebral ischemia and reperfusion-induced injury due to its antioxidating effect.