1.Optical quality evaluation of pseudophakic eyes implanted different materials of IOL by optical quality analysis system
Yinjuan, WEI ; Hui, SONG ; Xin, TANG
Chinese Journal of Experimental Ophthalmology 2016;34(3):248-253
Background Phacoemulsification with IOL implantation can reduce the light scattering caused by cataract,but many patients with IOLs implantation complained of glare or blurred vision.IOLs from different materials will affect IOL refractive index (RI) and optical design,which affect the value of scattered light of IOLs implantation.Objective This study was to analyze the effect of IOL materials on optical quality in pseudophakic eyes with optical quality analysis system (OQAS).Methods The clinical data of 95 eyes from 65 patients with age-related cataract who received phacoemulcification with IOL implantation in Tianjin Eye Hospital from March to Octomber were retropectively analyzed.Three types of lOL,including AR40e,Acrysof SA60 AT and Rayner 620H,were implanted in 32 eyes,30 eyes and 33 eyes,respectively.The visual quality indexes were detected and evaluated using OQAS,including uncorrected distance visual acuity (UCDVA,LogMAR),objective scatter index (OSI),modulation transfer function cut off (MTF cut off),strehl ratio (SR),Profile width at 50% point scatter function (PSF),Profile width at 10% PSF and contrast visual acuity under the 100%,20%,9% contrasts.Results The UCDVA was ≥ 0.3 in the eyes of AR40e group,SA60AT group and 620H group 1 month after surgery.No significant difference was found in the best corrected distance visual acuity (BCDVA,LogMAR) among three groups (F =1.362,P =0.246).The OSI was 1.72±1.11,1.89±1.07 and 2.13±1.13 in the AR40e group,SA60AT group and 620H group,with a significant difference among the groups (F =3.638,P =0.045),and the OSI was significantly lower in the AR40e group than that in the SA60AT group or 620H group (both at P<0.05).No considerable difference in MTF cut off among the groups (F =2.401,P =0.192).The SR value was significantly elevated and the PSF at both 50% and 10% was declined in the AR40e group compared with the SA60AT group and 620H group (all at P<0.05).A significant difference was found in 9% contrast visual acuity among the three groups (F=3.866,P=0.038),and 9% contrast visual acuity was better in the AR40e group than that in the SA60At group or the 620H group (both at P< 0.05).Negative correlations were found betwee OSI and BCDVA in the AR40e group,SA60AT group and 620H group (r=-0.275,P=0.041;r=-0.287,P=0.042;r=-0.233,P=0.037).Conclusions OQAS can evaluate optical quality of cataract patients after opeartion objectively.Material and RI of IOL have a great effect on visual quality after phacoemulcification with IOL implantation,especially under the low contrast environment.The operated eyes implanted hydrophobic acrylic IOLs with a lower RI can get better optical quality in comparison with the eyes implanted hydrophilic IOLs.
2.Imaging manifestations and its clinical significance in patients with synovitis acne pustulosis hyperostosis osteomyelitis syndrome
Wei YU ; Qiang LIN ; Jinpeng YAO ; Yinjuan CHANG ; Xiaohong ZHOU
Chinese Journal of Radiology 2012;46(9):816-819
Objective To describe the clinical and imaging manifestations of patients with synovitis acne pustulosis hyperostosis osteomyelitis (SAPHO) syndrome,and to analyze the diagnostic importance of different clinical and imaging manifestations for SAPHO syndrome. Methods Seventeen patients (7 males and 10 females) with SAPHO syndrome were recruited in this study.Age ranged from 36 to 67 years with a mean age of (48 ± 8) years. All patients fulfilled the diagnostic criteria of Benhamou. Serum HLA B27 antigen records were reviewed for all patients. Imaging data of the abnormal bone sites were collected by conventional radiograph in all patients,CT in 13 patients as well as MR in 3 patients.Average time to take for a definite diagnosis of the syndrome was 3.7 years (ranged from O.5 to 13 years).Results Serum HLA B27 antigen was positive in all patients. Both skin and bone abnornalities were found in all patients.Ten patients had skin palmoplantar pustulosis and two patients had acne. Involving sites of bone and joints include sacroiliac joints,anterior chest and limbs.Sacroiliac joints were asymmetrically involved with imaging features in all patients.Eight patients exhibited anterior chest wall involvement. Five patients had osteomyelitis at limbs. For all images of 17 patients,CT was superior to conventional radiography in detecting abnormal changes of bone erosion and soft tissue swelling.MR imaging was able to depict edema changes that was not detectable by CT and radiography.Conclusion SAPHO syndrome is a rare disease,but for patients with skin and bone-joint abnormalities,especially with skin palmoplantar pustulosis,acne as well as with imaging features at the sacroiliac joint and anterior chest wall,SAPHO syndrome should be taken into a diagnostic consideration.
3.Clinical diagnosis and treatment strategy for recurrent aneurysmal bone cysts of the extremities: a report of 29 cases
Haijun TANG ; Yun LIU ; Zengming XIAO ; Yinjuan LAI ; Jianghong LIU ; Changwu WEI
Chinese Journal of Clinical Oncology 2018;45(24):1254-1257
Objective: To explore the clinical characteristics, imaging feature, surgical outcomes, and prognosis of recurrent aneurysmal bone cysts (RABC) of the extremities. Methods: Between January 2008 and January 2016, 29 patients histopathologically diagnosed with RABC were treated at our hospital. These patients included 15 males and 14 females. The mean age at the time of diagnosis was 17.4 years(range 4-42 years). The most common site of the RABC was the proximal tibia (12 cases), followed by the distal femur (11 cases), and 3 cases each with involvement of the proximal humerus and the proximal femur. Recurrence was most commonly ob-served within 24 months following the initial treatment. Intralesional re-curettage was performed in 24 patients and en bloc resection of the tumor and reconstruction in 5 patients. The medial tibial stress syndrome (MTSS) score was used to evaluate postoperative func-tion of the affected limb, and the comprehensive clinical efficacy was evaluated on the basis of the Mankin criteria. Results: The mean follow-up duration was 64 months (range 24-90 months). Re-recurrence occurred in 1 patient with a total re-recurrence rate of 3.4%. The postoperative MTSS score was 26-30 points (mean 29.1 points) in the intralesional re-curettage group and 21-27 points (mean 23.0 points) in the tumor resection group. Based on the Mankin criteria, excellent and good clinical outcomes were observed in 95.8% of patients in the intralesional and 60% of the patients in the tumor resection and reconstruction groups. Conclusions: Regular follow-up is essential for the early diagnosis of RABC. The re-recurrence rate following intralesional re-curettage was within an acceptable range, and postoperative limb function was satisfactory; therefore, intralesional re-curettage is the treatment of choice for RABC in-volving the extremities. Tumor resection can be performed in patients with severe articular surface destruction and repeated recur-rence, although long-term complications may occur.
4.Change of corneal biomechanical properties caused by phacoemulsification using corneal visualization Scheimpflug technology
Lingxiao XU ; Yinjuan WEI ; Hui SONG
Chinese Journal of Experimental Ophthalmology 2018;36(2):140-143
Objective To explore the corneal biomechanical characteristics change in cataractous eyes before and after phacoemulsification using corneal visualization Scheimpflug technology (Corvis ST) and evaluate the influence of 3 mm clear corneal incision on corneal biomechanics.Methods A self-control study was performed.Thirty-six eyes of 36 patients who received phacoemulsification were enrolled in Tianjin Eye Hospital from March to May 2015.The first/second applanation time,the first/second applanation length,the first/second applanation velocity,the highest concavity time,the highest concavity radius,peak distance (PD),deformation amplitude (DA),intraocular pressure,corrected intraocular pressure and central corneal thickness(CCT) were measured in preoperation,postoperative 1 week and postoperative 1 month.This study protocal was approved by Ethic Committee of Tianjin Eye Hospital,and written informed consent was obtained from each patient prior to any medical examination.Results The first/second applanation length,intraocular pressure,corrected intraocular pressure,PD,DA and CCT were significantly different among preoperation,postoperative 1 week and postoperative 1 month (F =3.42,5.24,4.21,3.82,3.91,4.03,3.62;all at P<0.05).Compared with the preoperative parameters,the first applanation length value was increased,and the second applanation length was reduced;the intraocular pressure and corrected intraocular pressure were elevated,and PD and DA values were increased,and the CCT was thicked in 1 week postoperative,with significant differences between the two time points (all at P<0.05).Compared with the postoperative 1 week,the first applanation length value was reduced,and the second applanation length value was increased;the intraocular pressure and corrected intraocular pressure were lowed,and PD and DA values were smaller,and the CCT was thinner in postoperative 1 month,showing significant differences between the two time points (all at P < 0.05).The first applanation length,the second applanation length,the intraocular pressure,corrected intraocular pressure,PD,DA and CCT in postoperative 1 month returned to the preoperative levels (all at P > 0.05).Conclusions Corneal biomechanical properties occur change in the early stage after phacoemulsification and return to normal in postoperative 1 month.