1.Relationship between the Token Test and Chinese aphasia with different types due to left hemispheric damages
Chinese Journal of Rehabilitation Theory and Practice 2000;6(2):49-52
In order to evaluate the effect of Token Test for comprehension ability of Chinese aphasia,33 aphasics with different types due to left hemispheric damages were conducted in this study of Token Test and Aphasia Battery in Chinese(ABC).The statistic analysis showed that the score of Token Test was significant correlated with the comprehension ability,word recognition and dictation of Chinese language,construction and visual-spatial function,praxia,calculation,attention and memory ability(P<0.01)and significant correlated with the severity of their aphasia(P<0.05).This study revealed that the score of Token Test was influenced by the type and the severity of Chinese aphasia especially the comprehension ability of speech and also influenced by attention,memory,praxia,visual-spatial function,cognition,etc.Token Test was a very sensitive test of measuring the comprehension ability for Chinese speech.
2.THE DISTRIBUTION OF CFU-C IN HUMAN FETAL BONE MARROW, LIVER, SPLEEN AND PERIPHERAL BLOOD
Hui XU ; Fuwen NIU ; Yinhua WANG
Acta Anatomica Sinica 1953;0(01):-
40 human fetuses were used in this study. The range of fetal age varied from 3 months to full terms. All fetuses used were normal and their parents were healthy. The CFU-C from bone marrow, liver, spleen and peripheral blood were studied in vitro with agar culture technique modified by Metcalf.Experiments proved that the CFU-C of bone marrow may be observed in the fetuses in 3rd month, however, it increased rapidly in 4th month and maintained higher level until the end of fetal life. The progenitor cell population was detected at very high level in liver from 4th month to 6th month fetuses. The number of CFU-C of fetal liver were low in 7—10th month. The circulating progenitor cells in peripheral blood of 4, 5 and 6-month fetuses Were on high level but it was lower than that of liver and bone marrow.
3.One Case of Transcortical Sensory Aphasia with Prominent Semantic Comprehension Disorder
Jianping Niu ; Yinhua Wang ; Xueqin Zhou
Chinese Journal of Rehabilitation Theory and Practice 1998;4(3):113-115
The paper reports one case patient of transcortical sensory aphasia with prominent semantic comprehension disorder. Clinical features were fluent aphasic output, serious auditory comprehension disorder,anomia and prominent disorder in word-lexical level comprehension. Repetition was a little difficult and was remarkably better than other test. There was serious alexia with agraphia, however, copy, series writing, visual spatial function and calculation were intact. His audition was norma1. He could distinguish not only non-word and non-verbal sound but also family member's and acquaintance's sound, but he couldn't understand their talking content. It should be distinguished from pure word-deafness and auditory agnosia- Moreover, we tried to discuss its mechanism.
4.Effect of CO2 laser assisted laryngoscope on glottic carcinoma
Ling XU ; Yinhua NIU ; Rige SU ; Shu ZHANG
Journal of Chinese Physician 2019;21(2):215-219
Objective To prospectively investigate laryngoscopy-assisted CO2 laser in the treatment of glottic laryngeal carcinoma.Methods 97 patients with early glottic laryngeal carcinoma in our hospital were selected and divided into control group (n =48) and observation group (n =49) according to random number table.The control group was treated with partial laryngectomy and the observation group was treated with laryngoscopy-assisted CO2 laser.The clinical efficacy,serum level of α1-acid glycoprotein (α1-AG) and ceruloplasmin (CER) after 10 min of the surgery and changes of the indicators of voice function [fundamental frequency jitter (jitter),the longest sound time (MPT),sound pressure level (SPL)] were observed and compared between the two groups,and the incidence of complications and quality of life (QOL) scores were statistically compared.Results The total remission rate in the observation group was 79.59% (39/49),which was higher than that in the control group 56.25% (27/48),with statistically significant difference (x2 =6.075,P =0.014).The levels of serum α1-AG and CER in the observation group 10 min after surgery were lower than those in the control group,with statistically significant difference (t =2.641,P =0.010,t =31.242,P =0.000).From 2 weeks after surgery to 3 months after surgery,SPL and MPT of two groups decreased first and then increased;Jitter increased first and then decreased,and the changing amplitude in the observation group was smaller than that in the control group,with statistically significant difference (P < 0.05).The incidence of complications in the observation group was 2.04% (1/49),which was lower than that in the control group 16.67% (8/48),with statistically significant difference (P < 0.05);3 months after surgery,the QOL score of the observation group was higher than that of the control group,with statistically significant difference (P < 0.05).Conclusions Supporting laryngoscope CO2 laser surgery can improve stress state and quality of life of early glottic laryngeal cancer patients,and the incidence of complications is low.It has little effect on voice function.
5.A flowchart for the diagnosis and differential diagnosis of post-stroke aphasia types in the Chinese language and treatment of post-stroke aphasia
Yinhua WANG ; Wanliang DU ; Xiaona YANG ; Jun YAN ; Wei SUN ; Jing BAI ; Jiong ZHOU ; Aihong ZHOU ; Jianping NIU ; Chuanling LI ; Jian WANG
Chinese Journal of Geriatrics 2022;41(4):488-496
This article aims to comprehensively review the concept, etiology, classification, classical cortical mapping, assessment, a proposed flowchart for the diagnosis and differential diagnosis, treatment, rehabilitation, mechanisms of development and recovery, prognosis, and influencing factors for post-stroke aphasia(PSA)types in the Chinese language.We emphasize the necessity and significance of neuroimaging assessment of the brain and blood vessels and neuropsychological assessment in the diagnosis and differential diagnosis of PSA in Chinese.We also recommend and encourage the use of the dichotomies of internal vs.external and anterior vs.posterior as a starting point, based on the association of anatomical locations of the brain and blood vessels with brain language areas and language disorders.A classification system of PSA in Chinese developed from this approach in the form of a flowchart is well-suited for guiding the clinical treatment of cerebral stroke.Incorporating the "four elements" , the flowchart enables convenient diagnosis, classification and differential diagnosis of PSA in Chinese and facilitates targeted and personalized rehabilitation planning to benefit the patient.This article introduces the use of memantine, piracetam, donepezil and other drugs for PSA treatment, evaluates clinical trials on memantine conducted in China and abroad and its mechanisms of action for the treatment of PSA, and discusses how rehabilitation therapy achieves therapeutic effects.For the treatment of PSA, clinical research and practice using drugs such as memantine, piracetam and donepezil in combination with non-pharmacotherapy and rehabilitation training should be promoted.