Objective: In order to discuss the application value of intensity/time(L/T) curves on the rehabilitation assess ment of prolapsed lumbar intervertebral disc. Method: 244 I/T curves of 111 cases including musculus tibialis anterior、 musculus fibularis longus、musculus extensor hallucis longus were measured. 56 cases were operated. Result: In the 11- 1cases, 24cases were normal, 83 cases were partial degeneration, 4 cases were complete degeneration, the positive ratio was 78.38％. The I/T curves in 56 operated cases, 4 cases were complete degeneration, 45 cases were partial degeneration, 7 cases were normal. In 87.50% cases the I/T curve accorded with operation. In 244 I/T curves, 115 curves were normal, 125 curves were partial degeneration, 4 curves were complete degeneration. The positive ratio were 52.05％.Conclusion: The application value of L/T curves was significant on the rehabilitation assessment of prolapsed lumbar intervertebral disc.

OBJECTIVETo evaluate safety and immunogenicity of inactivated hepatitis A vaccine in HBsAg carriers and healthy children.

METHODSOne hundred and twenty-one healthy children and ten HBsAg carriers, aged 1-10 years HAV susceptible were enrolled in the study. The inactivated hepatitis A vaccine was produced by Tangshan Biogenetic Company. The dosage of the vaccine was 1000 U/Dosage and 500 U/Dosage. The vaccination schedule was six month apart for two injections. The serum anti-HAV level was detected with EIA at one month after first injection and at one and six month after the booster injection, respectively.

RESULTSThe anti-HAV appeared in all the children. One month after the booster injection, the serum anti-HAV level in children vaccinated 500 U/Dosage was 4684.9 mIU and 4535.6 mIU, respectively and in the children vaccinated 1000 U/Dosage, 5399.8 mIU and 7347.1 mIU, respectively. The anti-HAV level was not statistically different between the two groups of children. There was no adverse reaction after the vaccination. The anti-HAV level was still high one year after first injection.

CONCLUSIONSThe data indicated that the safety and immunogenicity of the domestic inactivated hepatitis A vaccine were excellent in both groups of children.

Child ; Child, Preschool ; Hepatitis A Antibodies ; blood ; Hepatitis A Vaccines ; immunology ; Hepatitis B Surface Antigens ; blood ; Humans ; Immunization ; Infant ; Vaccines, Inactivated ; immunology