1.Etiology and anti-infection treatment of severe infectious pneumonia in neonate
Chinese Pediatric Emergency Medicine 2017;24(5):340-345
The morbidity and mortality rate of neonatal infectious pneumonia take the first place in neonatal infectious diseases.Neonatal infectious pneumonia is also one of the main causes of neonatal death.Severe pneumonia could cause multiple organ inflammatory reaction and dysfunction.The etiology of neonatal severe infectious pneumonia is mainly exposure to pathogen and neonatal hypoimmunity.The passways inducing infection include prenatal,intrapartum and postpartum infection.Bacteria is the first pathogen in neonatal severe pneumonia and Gram-negative bacteria is the main pathogenic bacteria.The main bacteria of hospital acquired infection are enzyme production and multiple drug-resistant bacteria.Key treatment is reasonable anti-infection treatment.
2.Absorption and transport characteristics of strontium onto three kinds of vegetables grown in the soil
Shujuan LIU ; Dong YAN ; Yingxue HE ; Xiaoyan JIANG ; Kuke DING
Chinese Journal of Radiological Medicine and Protection 2015;35(5):376-379
Objective To explore the transport properties of the radionuclide strontium 90Sr in the soil-plant system,and discuss the accumulation characteristics of strontiumes in different vegetable tissues.Methods Three kinds of vegetables,including Chinese cabbage,radish and celery,were planted in this experiments using stable nuclide 88Sr instead of 90Sr.Strontium concentrations in these kinds of plant and soil were measured with inductively coupled plasma atomic emission spectrometry (ICP-AES),and the transportation factor (TF) of strontium and the concentration ratio (CR) of these plants were calculated.Results The contents of strontium in different tissues of the vegetables increased significantly in response to the strontium concentrations in soil (F =3.75-139.39,P < 0.05).The contents of strontium at 398.33,477.99 and 557.57 mg/kg in different tissues of these vegetables were significantly higher than that in control group (t =-10.49-7.41,P <0.05).Except celery stems,there was a positive correlation about contents of the strontium between other tissues of these vegetables and their experimental soils (r =0.88-0.99,t =7.41-15.96,P <0.05).Based on dry weight of examples,the TF in each tissue sample of cabbage and radish was higher than 1,and the concentration ratio,for cabbage and radish,was higher in stems than in roots (F =8.22,91.49,P < 0.05).Conclusions Three kinds of vegetables have been shown to have strontium accumulation ability in soil environment.
3.Relationship between dynamic changes of Epstein-Barr virus and efficacy of lymphoma
Yingxue YANG ; Kaiyang DING ; Maogui HU
Journal of Leukemia & Lymphoma 2018;27(6):336-339
Objective To observe the relationship between the dynamic changes of Epstein-Barr virus (EBV) and the clinical efficacy of lymphoma. Methods The retrospective study was performed on 51 lymphoma patients with EBV-positive in Anhui Provincial Cancer Hospital from September 2015 to August 2017. The treatment effect of lymphoma was evaluated by the changes of EBV DNA, lactic dehydrogenase (LDH) and lymph nodes. Results Among the 51 lymphoma patients, EBV DNA elevated in 18 patients when the LDH was elevated, 23 cases presented with EBV DNA decrease and the LDH also decreased. EBV DNA decreased in 2 patients when the LDH was elevated. Eight patients were elevated when LDH was reduced. The quantification of EBV DNA and LDH had high consistency (κ = 0.609, P= 0.000). Among the 51 lymphoma patients, 20 patients with elevated EBV DNA were elevated with lymph nodeen largement, the lymph nodes in 22 cases with EBV DNA decrease were also decreased. EBV DNA decreased in 3 patients when the lymph nodes were enlarged. Six patients were elevated when lymph nodes were reduced. The quantification of EBV and lymph nodes had high consistency (κ = 0.648, P= 0.000). Patients with elevated EBV DNA during the course of treatment showed an increase in the mean value of LDH, and the patients with reduced EBV DNA during treatment also had lower average LDH. LDH levels were positively correlated with EBV DNA in patients with EBV-positive lymphoma (r= 0.627, P= 0.000). Conclusion Dynamic detection of EBV DNA and LDH can be used as the evaluation index of therapeutic effect and follow-up in patients with EBV-positive lymphoma.