AIM To explore the effects and mechanism of cobra venom serum on the proliferation in HL60 cells. METHODS Established the HL60 cells as a target to study the growth feature by the action of cobra venom serum.The agarose gel electrophoresis and flow cytometry analysis were used to demonstrate apoptosis. RESULTS Compared with the control group, the cells were inhibited significantly by the action of cobra venom serum.A characteristic DNA "ladder" was detected by using agarose gel electrophoresis. By flow cytometry analysis,it was proved that most apoptosis of HL60 cells occurred when cultured with cobra venom serum. CONCLUSION Cobra venom serum inhibited the HL60 cells in vitro , which was related to apoptosis. This may introduce a new way to the treatment of leukemia.

In the present study, 15 complete RAs were selected respectively from English and Chinese medical journals based on the principles of representativity, reputation, accessibility and timeliness. Moves and steps were determined with reference to Swales and Nwogu's models, and their distribution and frequency were recorded and genre comparative analysis was performed. The results showed that the English and Chinese RAs shared generally the similar generic structure of 11 common moves. However, obvious cultural differences were found in the frequency, sequence and length between the two corpora. The findings of the present study will provide a practical guide for Chinese medical workers to have their papers published in English medical journals.

Objective To get to know the genre structure of clinical medical papers in English and to improve the reading and writing abilities of medical workers.Methods Fifteen clinical medical papers from New England Journal of Medicine,The Lancet,Journal of the American Medical Association and British Medical Journal were randomly selected and analyzed based on Swale's CARS model;with reference to the language clues,their moves and steps,as well as their language features,were recorded.Results There were 10 common moves-presenting background information,reviewing related research,announcing present research,clarifying study design,performing data analysis,reporting objective result,highlighting overall outcome,explaining main findings,indicating limitations,stating conclusions-in English clinical medical papers,and each move had its own steps and language features.Conclusion The English clinical medical paper has its common genre structures,and understanding their language features will help Chinese medical workers develop high-quality international academic exchanges.