1.Extraction Technology of Volatile Oil from Qingjie Granules and Optimization of Inclusion Technology by Box-Behnken
Yingnan TANG ; Ying PENG ; Lin TANG ; Lili ZHOU ; Xinhua XIA
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(8):70-75
Objective To optimize the extraction of volatile oil from Qingjie Granules and process of inclusion compound of beta-cyclodextrin. Methods Water Distillation was used for extraction. Extraction time, grinding degree, and the amount of water were set as inspection factors, and volatile oil volume was set as the evaluation index to inspect extraction process of volatile oil from Qingjie Granules. With inclusion rate as the evaluation index, the single factor test and the Box-Behnken combined with the response surface method were used to choose the optimum inclusion process. Results The optimum extraction process for Schizonepetae Herba, Saposhnikoviae Radix and Forsythiae Fructus coarse powder should be with 10 times amount of water, extracting 3 h. Inclusion method should be saturated water solution method, and the inclusion process of volatile oil as feed and beta-cyclodextrin inclusion ratio was 1:12; the temperature was 40 ℃; inclusion time was 3.5 h. By means of TLC, UV and IR spectra, the formation of the inclusion compound of volatile oil in clear solution particles was preliminarily proved. Conclusion The optimum extraction and inclusion process of volatile oil from Qingjie Granules are stable and feasible, which can be used in industrial production.
2.Working Mode and Case Analysis of the First Pharmaceutical Ward Rounds in Our Hospital
Wei ZHUANG ; Suying YAN ; Xiaolan LIN ; Fei CHEN ; Li GAO ; Yingnan FENG ; Jing TANG ; Beibei JIA ; Yanqi CHU
China Pharmacy 2021;32(17):2129-2133
OBJECTIVE:To est ablish the working mode of the first pharmaceutical ward rounds of clinical pharmacists in our hospital,in order to provide a useful reference for establishing a national standardized pharmaceutical ward rounds model. METHODS:By sharing the clinical cases of the first pharmaceutical ward rounds ,the work content and process of the first pharmaceutical ward rounds in our hospital were introduced. RESULTS & CONCLUSIONS :The clinical pharmacist ’s first pharmaceutical ward round in our hospital mainly includes self introduction of clinical pharmacists ,diagnosis of patients ’condition under the guidance of doctors ,collection and evaluation of patients ’previous medication information (including previous medication varieties ,usage methods ,efficacy and safety evaluation ),assistance for doctors in formulating initial treatment plan , carrying out initial medication and diet education ,and intensive communication and cooperation with nurses. The development of first pharmaceutical ward rounds promotes the rational use of drugs in clinic ,elevates the hospitalization satisfaction of patients and improves the professional quality of clinical pharmacists.