Objective:To investigate the relationship between serum cytokines(IL-1?, IL-6 and TNF-?) and post-stroke depression. Methods:Serum IL-1?, IL-6 and TNF-? in stroke patients(n=32)and post-stroke depressive patients (n=32)were measured by ELISA on day 7 and day 28 after stroke.Results:The serum levels of IL-1?, IL-6 and TNF-? of the study group in day 28 were higher than that of control group (41.0?4.4/17.6?3.2, 13.5?4.1/5.4?2.0, 34.5?7.6 /20.8?4.3,P

Objective To study current situations of occupational burnout and humanistic care ability of the nurses in our hospital and explore the relationship between them. Method Nursing burnout scale (NBS) and caring ability inventory(CAI) were adopted in the investigation among 542 nurses in our hospital. Results The total score on the nursing burnout of the nurses of my hospital was 96 to 214, with an average of (155.04 ± 17.01). The burnout among 245 of them (45.20%) was in mild to moderate degree and that among 155 of them (28.60%) in a severe level. The score on humanistic care ability was 94 to 253 with an average of (178.14 ± 23.66). The ability among 46.31%of them was at a middle level and that among 25.46%of them at a low level. The occupational burnout of the nurses was negatively correlated with their humanistic care ability as well as with its three dimensions of cognition, courage and patience (P<0.01). Conclusions The occupational burnout can be alleviated by reducing the pressure in their caregiving practice. Their humanistic care ability can be enhanced by improving humanistic care nursing education and bettering humanistic care system.

Objective To establish the reference ranges for fetal cardiac axis in the mid-second trimester and to evaluate the use of fetal cardiac axis in prenatal diagnosis.Methods 6744 unselected singleton pregnancies were enrolled from September 2008 to October 2010.Routine screening scan of second trimester and fetal echocardiography were performed at 18- 23+6 weeks gestation.Fetal cardiac axis was measured on the four-chamber view of the heart.Results The 6744 fetuses had a mean cardiac axis of (37.03 ± 6.10)°,ranging from 9.80° to 102.41°. Using above or below 95％ range of population (26.63° -49.40°) as a cut-off,there were significant difference of cardiac axis between normal group [(36.96 ± 5.91)°,P ＜0.01] and the group with heart defects [(43.12 ± 15.67)°,P ＜0.01],the group with intrathoricic anomalies or abdominal wall defect [(51.74 ± 15.97)°].ConclusionsThe reference ranges of fetal cardiac axis for local population in mid-second trimester may helpful for detecting congenital defects.Presence of an abnormal cardiac axis in the fetuses is associated with a substantial risk of congenital heart disease and/or other extra cardiac defects.

Cerebral microbleed (CMB) is a type of cerebral small vessel disease (CSVD). Recently studies have found that there is a certain relationship between CMB and cognitive impairment. This article mainly reviews the etiology of CMB, the relationship between CMB and cognitive impairment, CMB and cognitive disorders and the possible mechanism of CMB-related cognitive impairment, in order to improve the understanding of cognitive impairment caused by CMB.