1.The influencing factors of retinal vessel caliber in type 2 diabetes mellitus
Chinese Journal of Postgraduates of Medicine 2010;33(25):28-31
Objective To study the influencing factors of retinal vessel caliber in type 2 diabetes mellitus and supply the elementary data for clinic. Methods Two hundred diabetic patients were involved in this study, and the vessel caliber was measured by fundus oculi color photo and computer-assisted imaging program. Biochemical indicator and blood pressure was examined and other document was achieved by questionaire. Results In type 2 diabetes mellitus, the retinal vein caliber had negative correlation with age and positive correlation with fasting blood glucose (FBG), glycosylated hemoglobin A1c (HbA1c) and the duration of diabetes mellitus(P < 0.01 ). The retinal arteriole caliber had negative correlation with age, blood pressure and the duration of diabetes mellitus (P < 0.01 or < 0.05 ). Conclusion The influencing factors of retinal vessel caliber in type 2 diabetes mellitus are age,FBG,HbA1c,blood pressure and the duration of diabetes mellitus.
2.The influence of the duration of type 2 diabetes mellitus on retinal vessel diameter
Chinese Journal of Primary Medicine and Pharmacy 2010;17(23):3204-3205
Objective To observe the signs of retinal vessel diameter among different clinical characteristic groups such as sex,age,BMI,the duration of DM. Methods200 diabetic patients were selected.Using face to face questionnaire survey forms filled in the questionnaire in order to collect the general situation of all subjects selected.The diameters of vessels were measured using a computer-assisted imaging program. ResultsIn type 2 diabetes mellitus,there was no significant difference in the retinal arteriolar and veular diameters between the groups with different sex.In type 2 diabetes mellitus,as age increased,both the retinal arteriolar diameters and the retinal veular diameters declined.In type 2 diabetes mellitus,there was no significant difference in the retinal arteriolar and veular diameters between the groups with different BMI.In type 2 diabetes mellitus,as the duration of DM increased,the retinal veular diameters dilated and the retinal arteriolar diameters declined.After storied in accordance with age,we can draw the sameConclusion . ConclusionIn type 2 diabetes mellitus,as the duration of DM increased,the retinal veular diameters dilated and the retinal arteriolar diameters declined.
3.Effects of Air Pollution on Non-special Immunity Function of Pupils
Hong YAN ; Yingjun XU ; Tiemin ZHANG
Journal of Environment and Health 1989;0(06):-
0.05). Conclusion Air pollution might have effect on pupils' non-special immunity.
4.Experimental Study on the Anti-inflammation Effect of Volatile Oil in Ramulus Cinnamomi
Shijun XU ; Yingjun SHEN ; Yuhuan XIE
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(03):-
objective To study the anti-inflammation effect of volatile oil from ramulus cinnamomi(VORC).Methods Anti-inflammation effect was studied with the methods of mice auricular swelling,mice celiac capillary permeability,rat hind paw edema and acute pneumonia model.Results VORC had an inhibitory effect on acute inflammation of mice induced by xylene,celiac capillary permeability of mice induced by acetic acid,edema of rat hind paw induced by carrageenan,acute pulmonary inflammation of rat induced by LPS.Conclusion VORC has a markedly anti-inflammation action.
5.Experience in treatment of Ambroxol combined with Naloxone for respiratory insufficiency in 86 premature infants
Yingjun SUN ; Yang CHEN ; Xiaojun XU
Clinical Medicine of China 2011;27(2):213-215
Objective To assess the effect of Ambroxol combined with Naloxone on respiratory insufficiency on premature infants. Methods A total of 168 premature infants treated from 2006 to 2009 in our hospital were divided into two groups randomly. Additionally to the conventional treatment, Ambroxol (5 mg pertime) combined with Naloxone (0.1mg pertime) intravenously injected 2 to 3 times one day for 3 to 5 days in the treatment group(86 cases). The control group (82 cases) was treated by routine Aminophylline injection,3- 5 mg/kg pertime, 2 to 3 times one day. Respiratory rates, regulately or not,breathholding, cyanosis and apnea,mechanically ventilated time,time of oxygen inhaling, time of hospital stay and the overall response rate were measured. Results The overall response rate was 80% (69/86) in the treatment group and 56% (46/82)in the control group, with significant difference between the two groups ( P < 0. 05 ). Mechanically ventilated time,time of oxygen inhaling and hospital stay in the treatment group was (110.5±45.1) hrs, (169.3±58.6) hrs and ( 12±3) days, which were all significantly lower than that in the control group ( 181.1±81.2) hrs, (236.6±87.8)hrs and (16±5)days,respectively(P<0.01 or 0.05). Conclusion Ambroxol and Naloxobe additional to conventional treatment could improve the respiratory function in premature infants with respiratory insufficiency safely with less side effects. Moreover,breathing machine could be removed to some extent,which made it more applicable in primary hospitals.
6.Protective effects of ischemia preconditioning and dexorubicin precondition ing on cryopreservation injury of ratlive
Song QIN ; Bei SUN ; Jun XU ; Yingjun TIAN ; Hongchi JIANG ;
Chinese Journal of General Surgery 1993;0(02):-
ObjectiveTostudytheprotectiveeffectsofpreconditioningoncryopreservationinjuryofrat liver.MethodsThemodelofisolatednonrecirculatedperfusionratliver (IPRL)wasestablished .Thegrafts werepreconditionedwithischemia (IPC)anddexorubicin (DPC)respectively .ResultsThelevelsofaspartate transaminase (AST)andalaninetransaminase (ALT)inthesolutionsinIPCgroup (40 1? 6 3、17 1? 0 5 )U L andDPCgroup (43 6? 3 7、19 4? 0 8)U Lwerelowerthanthoseofnon preconditioning (NPC)group (6 4 5? 8 2、2 3 8? 3 96 )U L (P 0 0 5 ) .ConclusionsPreconditioninghasobviousprotectiveeffectsoncryopr eservationinjuryofratliver.MedicinepreconditioningmightimitatetheeffectofIPC .Medicinepreconditioning cansupplyclinicaltreatmentasasafeandeffectivepreconditioningmethod .
7.Ward Calling System Based on Power Line Communication
Ping XIONG ; Yingjun LEI ; Min XU ; Xue MENG
Chinese Medical Equipment Journal 2003;0(11):-
Objective To introduce ward calling system based on power line communication. Methods The system is de- signed based on SCM and spread spectrum communication chip. It adopts principal and subordinate structure, transmits data on low-voltage power line. The spread spectrum communication chip is SC1128, which is specially designed for Chi- nese low power line. Results The system can communicate correctly in testing, and the max communication distance is 500m. Conclusion The system have many functions such as line up shows, priority setting, records storage, etc. It has been fit to be put into use and be extended in all of the various levels of hospital.
9.Optimization of the Extraction Process of Bi Xie Fen Qing Drink Using Ultrasound-Microwave Cooperation with Central Composite Design-Response Surface Method
Yingjun YE ; Zijin XU ; Hui CHEN ; Jianming LIU ; Mochang QIU
World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(2):351-358
This study aimed at optimizing the extraction process of Bi Xie Fen Qing (BXFQ) drink using ultrasound-microwave cooperation with central composite design-response surface method in comparison with the traditional decoction process.Taking microwave frequency,amount of water,extraction time as the main detection factors,diosgenin,glycyrrhizic acid and the extract yield were tested as the evaluation indexes;and taking an integrated score as response value for response surface and contour,predictive analysis was carried out and the optimum extraction conditions were achieved.It was found that the optimum extraction process of BXFQ drink was identified:the microwave frequency was 434 W,water addition was 18.4 times,extraction time was 9.3 mins and the ultrasonic frequency was fixed at 50 W.Under the optimum process,the diosgenin extraction yield rate was 23.17% (mg· g-1),extraction yield rate of glycyrrhizic acid was 0.64% (g·g-1),and the extraction yield rate of extractum was 34.12% (g·g-1).All the indexes were superior to those of the traditional method.It is concluded that the composite design-response surface method is suitable for the extraction optimization of BXFQ drink with favorable predictability of the mathematical model.The optimized ultrasoundmicrowave cooperation was easy to operate with high extraction efficiency.It is suitable for industrialized production with the provision of a scientific reference for the modern formulation development of BXFQ drink.
10.Clinicopathologic changes of gigantomastia
Na WANG ; Yong LI ; Yingjun SU ; Chen XU ; Ming LEI
International Journal of Surgery 2013;40(10):665-668,封3
Objective To study the clinical and pathologic changes in gigantomast.Methods Tissue sections were prepared from 180 cases of breast hypertrophy and 45 cases of normal breast tissues.The morphological changes and the expression and localization of ERRγwere evaluated on the HE and immunohistochemistry stained sections between hypertrophy and normal breast tissues.Results Compared with normal breast,hypertrophic breast showed expended ducts and obvious hyperplasia of the duct epithelial papillary.Hypertrophic breast tissues demonstrated strong expression of ERR-γ in ducts and lobules.Conclusions Upregulated expression of ERRγ is identified in hypertrophic breast tissues that may associate with the development of gigantomastia.