Objective To study the effects of the active components of eight kin ds of Chinese herbs on cytochrome P450 enzymes (CYP) 1A1,2E1,3A4 and 3A5 mRNA expression. Methods The mRNA expression levels of four CYP enzymes were determin ed by real-time quantitative reverse-transcriptase polymerase chain reaction. Results Baicalin,baicalein and artemisinin induced CYP1A1 expression at differe nt concentrations. Compared with baicalin and baicalein,the effect of artemisin in was weaker. The expression of CYP3A4 gene was significantly obvious after ind uced by sodium aescinate,baicalein and artemisinin. Conclusion HepG2 cells shou ld be an appropriate in-vitro system for investigating potential human CYP indu cing agents. CYP1A1 and CYP3A4 expression could be significantly induced by baic alin,baicalein,artemisinin and sodium aescinate,which would supply the eviden ce for the interaction of herbal medicine and western medicine based on cytochro me P450 and toxicology.

Mexico has close economic cooperation with China, which boosts with rich herbal medicine resources. Its traditional medicine share great similarity with Traditional Chinese Medicine (TCM) in both theory and form. Some of its traditional medicine and Chinese herbal medicine are the same in practice. The Mexico government pays great attention to the higher education of traditional medicine, and people are easy to accept traditional medicine treatment. The development of acupuncture and moxibustion in Mexico is good. Thus, to develop the service trade of TCM in Mexico has obvious advantages. At present, the local laws and regulations on TCM are not perfect. There are some problems in the development of TCM service trade, such as the lack of cross-border delivery platform, the small scale of business, and the weak attraction of natural person flow. Based on the concept of global health governance, this paper puts forward some measures to promote the development of TCM in Mexico, such as developing industrial chain or relying on overseas traditional medicine center.

Triggering receptor expressed on myeloid cells-1 (TREM-1), which plays a major role in the pathogenesis of infectious and non-infectious inflammation, is an important inflammation regulator. This article reviewed the structure and forms of TREM-1, mechanism on regulation of inflammation and relationship with immune-related intestinal diseases, thereby to investigate the role and potential value of TREM-1 on diagnosis, prognosis prediction and treatment target in immune-related intestinal diseases.

Rats ; Animals ; Adipose Tissue, Brown/physiology* ; Adipose Tissue