Objective To observe the effect and safety of orthokeratology in myopia patients.Methods Sixty-eight(136 eyes)young patients with myopia wore orthokeratology lens as research group,and 55 cases(110 eyes)young patients with myopia wore glasses as control group,clinical data of both groups were retrospectively analyzed to evaluate the role of orthokeratology lens on controlling the progression of myopia.Results After treatment,uncorrected visual acuity of research group significantly improved (0.76 ± 0.15 vs.0.40 ± 0.13,P ＜ 0.05),while spherical equivalent(SE)and corneal curvature significantly reduced[(-2.63 ± 1.06)D vs.(-3.52 ± 1.25)D,(42.30 ± 1.25)D vs.(43.21 ± 1.28)D,P ＜ 0.05].After treatment,SE of control group significantly increased[(-4.65 ± 1.29)D vs.(-3.55 ± 1.27)D,P ＜ 0.05],axis oculi significantly prolonged[(25.16 ± 0.55)mm vs.(24.30 ± 0.53)mm,P ＜ 0.05].Research group had no serious corneal infection happened during the treatment.Conclusion Orthokeratology lens can effectively reduce the degree of myopia and slow down the axis oculi growth,and it is used convenient with high security.

Objective To investigate the clinical efficacy and safety of phaocemulsification and intraocular lens combined with goniosynechialysis(Phaco + IOL + GSL) for treating the patients with primary angle closure glaucoma(PACG) with cataract.Methods 136 cases (141 eyes) PACG and cataract patients underwent the surgical treatment,their clinical data were retrospectively analyzed.67 cases(69 eyes) underwent Phaco + IOL + GSL surgical treatment(treatment group) and 69 cases (72 eyes) underwent Phaco + IOL + TBL surgical treatment (control group).The surgical treatment effects were compared and analyzed between two groups.Results At postoperative 1-month,3-months,6-months and 12-months,the intraocular pressure of treatment group was (13.32 ± 1.63) mm Hg,(14.43 ± 1.84)nn Hg,(14.65 ± 1.80) mm Hg and (14.73 ± 1.88)mm Hg respectively,the visual acuity was (0.423 ± 0.091),(0.472 ± 0.088),(0.615 ± 0.109) and (0.682 ± 0.127) respectively,the anterior chamber depth was (2.75 ± 0.59) mm,(2.97 ± 0.56) mm,(3.25 ± 0.58) mm and (3.41 ± 0.64) mm respectively.The intraocular pressure of control group was (17.35 ± 2.13)mm Hg,(16.87 ± 2.15) mm Hg,(16.31 ± 2.00) mm Hg and (15.68 ±2.02)ram Hg respectively,the visual acuity was (0.321 ±0.069),(0.362 ±0.062),(0.354 ±0.069)and (0.381 ±0.088) respectively,the anterior chamber depth was (2.21 ±0.48)mm,(2.35 ±0.40)mm,(2.41 ±0.47)mm and (2.43 ± 0.56)mm respectively.Compared with the control group,the intraocular pressure significantly reduced,visual acuity significantly increased and anterior chamber depth significantly increased of treatment group in posto perative 1-month,3-months,6-months and 12-months(all P ＜0.05).There were no serious complications in the two groups.Concluslon The triple therapy of Phaco + IOL + GSL has better clinical efficacy and security,and the therapy is worthy of clinical application.