1.Ultrasonic characteristics and diagnostic value of different molecular types of breast cancer with maximum diameter within 2 cm
Xiaoyu CONG ; Yingfen DA ; Cheng WANG ; Xinfeng LIANG ; Min CHEN ; Jie YUAN
Journal of Clinical Medicine in Practice 2023;27(24):20-25
Objective To investigate the clinicopathological and ultrasonic characteristics of dif-ferent molecular types of breast cancer with maximum diameter ≤2 cm,and analyze the diagnostic val-ue of conventional ultrasound.Methods A total of 174 breast cancer patients with diameter ≤2 cm were selected as the study objects.According to the immunohistochemical results,they were divided in-to LA group(Luminal A,n=46),LB group(Luminal B,n=71),HER-2 group(HER-2 overexpres-sion type,n=11)and triple-negative group(triple-negative,n=46).The clinicopathology,ultrasonic characteristics and the accuracy of conventional ultrasonic diagnosis were analyzed.Results There were significant differences in breast cancer size,pathological grade and pathological type among four groups(P<0.05).Among the ultrasonic characteristics,there were statistically significant differ-ences in shape,edge,aspect ratio,calcification and rear echo among the four groups(P<0.05).Breast Imaging Reporting and Data System(BI-RADS)grading and accuracy of conventional ultra-sound diagnosis among the four groups showed statistically significant differences(P<0.05).Conclusion The clinicopathological features,ultrasound features and BI-RADS grading of different molecular types of breast cancer with maximum diameter ≤2 cm are different.Routine ultrasound has certain diagnostic value,which can provide important reference for molecular classification diagnosis,individualized treatment and prognosis evaluation of early breast cancer.
2.Ultrasonic characteristics and diagnostic value of different molecular types of breast cancer with maximum diameter within 2 cm
Xiaoyu CONG ; Yingfen DA ; Cheng WANG ; Xinfeng LIANG ; Min CHEN ; Jie YUAN
Journal of Clinical Medicine in Practice 2023;27(24):20-25
Objective To investigate the clinicopathological and ultrasonic characteristics of dif-ferent molecular types of breast cancer with maximum diameter ≤2 cm,and analyze the diagnostic val-ue of conventional ultrasound.Methods A total of 174 breast cancer patients with diameter ≤2 cm were selected as the study objects.According to the immunohistochemical results,they were divided in-to LA group(Luminal A,n=46),LB group(Luminal B,n=71),HER-2 group(HER-2 overexpres-sion type,n=11)and triple-negative group(triple-negative,n=46).The clinicopathology,ultrasonic characteristics and the accuracy of conventional ultrasonic diagnosis were analyzed.Results There were significant differences in breast cancer size,pathological grade and pathological type among four groups(P<0.05).Among the ultrasonic characteristics,there were statistically significant differ-ences in shape,edge,aspect ratio,calcification and rear echo among the four groups(P<0.05).Breast Imaging Reporting and Data System(BI-RADS)grading and accuracy of conventional ultra-sound diagnosis among the four groups showed statistically significant differences(P<0.05).Conclusion The clinicopathological features,ultrasound features and BI-RADS grading of different molecular types of breast cancer with maximum diameter ≤2 cm are different.Routine ultrasound has certain diagnostic value,which can provide important reference for molecular classification diagnosis,individualized treatment and prognosis evaluation of early breast cancer.
3.Diagnostic Value of Micropure Imaging Combined with Strain Elastography in Correcting Artificial Intelligence S-Detect Technology for Benign and Malignant Breast Complex Cystic and Solid Masses
Jie YUAN ; Cheng WANG ; Yingfen DA
Chinese Journal of Medical Instrumentation 2024;48(4):426-429,439
Objective To explore the diagnostic value of micropure imaging(MI)combined with strain elastography(SE)in correcting artificial intelligence(AI)S-Detect technology for benign and malignant breast complex cystic and solid masses.Methods The S-Detect diagnosis results were corrected based on the manifestations of MI and SE of the 145 breast complex cystic and solid masses.Postoperative pathological results were used as the gold standard to calculate the diagnostic sensitivity,specificity,and accuracy before and after correction.Additionally,receiver operating characteristic(ROC)curves were drawn for both groups,and the areas under the curves were compared.Results There were 80 benign and 65 malignant pathological results.After the correction of S-Detect,the diagnostic sensitivity,specificity,and accuracy,as well as the areas under the ROC curves,were all improved compared to before the correction.Conclusion Combining MI and SE to correct the diagnostic results of S-Detect can help improve the diagnostic efficacy of breast complex cystic and solid masses.