1.Status quo research and analysis of clinical abilities in higher vocational college nursing students
Meiqin ZHANG ; Hongmei TANG ; Jiajie CHEN ; Yuxiao LIU ; Yingda GUO ; Fengping LI
Chinese Journal of Modern Nursing 2018;24(12):1475-1477
Objective To explore the current status of clinical ability in higher vocational college nursing students, and the necessity of action oriented practice examination model in higher vocational college nursing teaching. Methods From January to December 2015, a total of 30 higher health vocational colleges which set nursing major in 17 provinces (municipality directly under the Central Government) were investigated. Totally 409 nursing interns were investigated by self-designed Clinical Practice Questionnaire Survey for Higher Vocational College Nursing Students, and 83 nursing staff were interviewed on the need of the abilities in nursing students. One investigation unit in each province or city was contacted, who was responsible for the release, recycle and mail of the questionnaires. The differences in the status score and the demand score of nursing students were compared, and the correlation among various dimensions were analyzed. Results There were statistical significance in the differences of scores in professional ability, method ability, social ability and each dimension of nursing students' clinical abilities (P<0.01). The result of correlation analysis indicated that there was no correlation between method ability and professional ability (P>0.05), on the other side, all the other dimensions were positively correlated (P<0.01). Conclusions The clinical ability in higher vocational college nursing students are correlated with professional ability, method ability and social ability. Thus, action oriented practice examination model formed according to that result have relatively feasibility.
2. Research progress on pathogenesis and potential therapeutic target of sarcopenia obesity
Yixun GUO ; Yingda WEI ; Yan ZHANG ; Xiaoyin GUAN ; Bo WANG ; Yan ZHANG ; Jianhua LIN
Chinese Journal of Clinical Pharmacology and Therapeutics 2023;28(3):341-346
Sarcopenia obesity (SO), a specific disease with co-occurrence of obesity and sarcopenia, is shown clinically as abnormal accumulation of fat, decreased mass and strength of muscle, and increased risk of incidence and mortality of other chronic diseases. Currently, there exist various definitions and diagnoses about SO in the various regions of the world. Its prevalence in populations elevates in an age-dependent manner. This article summarized the possible pathogenesis of SO from the view of chronic inflammation, oxidative stress, insulin resistance, and Hippo pathway, subsequently listed and analyzed potential pharmacological targets (fibroblast growth factor, CD44, adiponectin, etc) involved in treating SO, in order to provide new ideas for clinical diagnosis, treatment of SO patients and research and development of innovative drugs.