1.Information construction and information sharing in Shenzhen public hospitals
Qian GAN ; Ying HU ; Weimei ZHONG
Chinese Journal of Medical Library and Information Science 2013;(12):47-49,54
The information construction and information sharing in Shenzhen public hospitals were investigated with their achievements and problems summarized .Suggestions were put forward for perfecting their information construction, improving their information sharing level, and realizing their regional medical information sharing for the reference in working out their information development program and making health information policies.
2.POSTOPERATIVE RADIATION THERAPY (RT) FOR BREAST CANCER CLINICAL ANALYSIS OF 314 CASES
Jingxu CAO ; Yinxian WANG ; Ying GAN
Chinese Journal of Radiation Oncology 1995;0(02):-
We analyzed retrospectively the result of postoperative RT by electron beam in 314 patients with breast cancer after a radical or modified mastectomy between 1976~1992. The radiation portals covered the supraclavicular, the axillary and the internal mammary lymph node chains and chest wall. D T40~50Gy/4~5w was delivered. The local regional failure and factors affecting the survival rates, such as the clinical stage, the status of axillary lymph nodes and radiation dose were analyzed. The symptomatic radiation pneumonitis (9.4%) was discussed.
3.The Reliability and Validity of MBI-SS and Academic Characteristics Affecting Burnout
Ying ZHANG ; Yiqun GAN ; Yiwen ZHANG
Chinese Journal of Clinical Psychology 2000;0(04):-
Objective: To examine the reliability and validity of MBI-SS and discuss the academic characteristics that affect burnout. Methods: 353 undergraduate students were administrated MBI-SS and Academic Characteristic Survey. Results: Confirmatory factor analyses showed that the expected three-factor structure of the adapted versions of the MBI- Students Survey (including Exhaustion, Cynicism, and Reduced Efficacy) fitted to the data. Exploratory factor analyses showed that the Academic Characteristic Survey includes six dimensions. The result of Regression showed that 44.4% variance of student burnout can be explained by Academic Characteristics. Conclusion: Student burnout includes three dimensions: Exhaustion, Cynicism and Reduced efficacy. Academic self-efficacy,academic stress,relationship with teachers and relationship with fellow students are significant predictors for student burnout.
4.Investigation of Children with Cerebral Palsy in Rehabilitation and Their Families in Shenzhen
Qian GAN ; Anyan ZHOU ; Ying HU
Chinese Journal of Rehabilitation Theory and Practice 2011;17(3):277-279
ObjectiveTo investigate the children with cerebral palsy (CP) in rehabilitation, their families and need of society support. Methods150 children with CP in rehabilitation participated in this study. A questionnaire was designed to investigate their basic situation, family status, society concern and requirements for society support, which completed by their parents. Results150 questionnaires were completed efficiently. 75 children were firstly treated before 1 year old. The rehabilitation treatments were effective to 130 children. 126 children appeared some disorder in emotion and personality. Home education was the main rehabilitation way in 133 children. The educational background of 59.4% mothers were senior high school or below. The income was less than 60 thousand yuan in 76.7% families, but spent more than 40 thousand yuan per year on treatment in 54.7% families. One or both parents in 119 families were forced to stop working. 93.3% of them suffered emotion pressure and 56.7% lacked the knowledge about CP. 81% families thought that more social support should be offered in 6 aspects including government welfare, social security, medical institutions, psychotherapy, community services and legal aid. ConclusionAll society should pay more attention on the children with CP and provide a good rehabilitation environment for them.
5.The study on ocular motor function of patients with Parkinson disease at early and moderate stage
Li YING ; Zhenguo LIU ; Wenan WANG ; Wei CHEN ; Jing GAN
Chinese Journal of Geriatrics 2008;27(7):514-517
Objective To study ocular motor function in patients with Parkinson disease.Methods Videonystagmography(VNG)was used for testing ocular saccade and smooth pursuit eye movement(SPEM)in 14 patients with idiopathic Parkinson disease and 10 age and sex-matched control subjects to compare the latency of saccades,the accuracy of saeeades and SPEMGain between two groups. Results The latency of saceades was found to be much more increased in PD group (291.23±46.25)ms than that in healthy group(244.45±23.11)ms(P<0.05);and the accuracy of saccades was found to be decreased in PD group(87.98±6.1 6)as compared to that in healthy group (95.21±8.56)(P<0.05).PD group was found to have more decreased SPEM gain(0.81±0.12)than that in healthy group(0.90±0.1 5)(P<0.05). Conclusions The findings suggest that ocular motor function is abnormal in Parkinson disease patients.
6.Autophagy and myocardial ischemia/reperfusion injury
Youbin LIU ; Shusen YANG ; Ying FAN ; Runtao GAN
Chinese Journal of Pathophysiology 2009;25(12):2478-2482
Autophagy is a lysosome-dependent degradative pathway which is characterized by cytoplasmic vacuolization. However, it is not just a simple degradative pathway. Research shows that autophagy is related to many diseases, such as neurodegenerative disease, malignant tumor, ageing, pathogenic microorganism infection, myocardial ischemia/reperfusion injury and so on. Autophagy exactly exists in myocardial ischemia/reperfusion injury, and it becomes a new research hotspot. This review will focus on the occurrence and development of autophagy and its role, signal transduction and research status in myocardial ischemia/reperfusion injury.
8.The experiment of interventional pulmonary lobectomy
Yufeng YOU ; Wanchong GAN ; Wei KE ; Wenhua YING
Journal of Interventional Radiology 1992;0(01):-
Objective To study the feasibility of interventional pulmonary lobectomy by animal experiment. Methods Twelve healthy dogs were divided into three groups randomly,with 4 in each. Group A: the target bronchus and alveoli were filled with emulsion of lapiodal and alveolar cells damage liquors and then the target bronchus was occluded with Polymethylmethacrylate(PMMA). Group B: The target bronchus was only occluded with PMMA. Group C: Pulmonary lobe was resected surgically. Arterial blood gases were measured at the time of pre-procedure and post-procedure and then 1st, 2nd, 3rd and 4th week after the procedure respectively. Chest radiography histology and bacterial culture of tissue of target lung lobe were made after 4 weeks. Results There was a significant difference in arterial blood-gas among 3 groups pre-procedure in comparion with those of post-proceduce immediately (P0.05) in comparing with 1st, 2nd, 3rd and 4th week after the procedure. Atelectasis was shown radiologically with histological formation of fibrosis of target lung lobe but no bacteria grew in target tissue 4th week after the procedure. There were two cases of lung atelectasis but no pulmonary fibrosis occluded in group B. Conclusions Interventional pulmonary lobectomy might be obtained after the target bronchus and pulmonasy alveoli were filled with emulsion of dipiodal and alveolar cells damage liquors and then the target bronchus was occluded with PMMA.
10.Progesterone on the expression of ADAM10,Ob-R and the secretion of SLR,LEP in human chorionic tropho-blast cells
Lei GAN ; Zhen LI ; Xiaohua WU ; Demei YING ; Liping CHEN
Journal of Regional Anatomy and Operative Surgery 2015;(3):249-252
Objective To investigate the different concentrations of progesterone on the expression of a disintegrin and metalloprotease 10 (ADAM10),long form leptin receptor (Ob-R) and the secretion of soluble leptin receptor (SLR),leptin (LEP) in primary pregnancy human chorionic trophoblast cells. Methods Cultured primary human trophoblast cells and added in different concentrations of progesterone (0,100,150 and 200 ng/mL) for 24 hours. The relative expression of ADAM10 and Ob-R in the cells and the content of SLR and LEP in the supernatant were detected. Results With increasing concentrations of progesterone,early human trophoblast cells ADAM10 content gradual-ly decreased,the difference between the two groups was significant (P<0. 05). With increasing concentrations of progesterone,human chori-onic trophoblast cells in early pregnancy Ob-R expression levels increased, the difference was no statistically significant between each two groups (P>0. 05). SLR content of the cell supernatants as the concentration of progesterone increased and decreased,there are significant differences between each two groups (P>0. 05). LEP cell supernatant in each group with the increase of the concentration of progesterone concentration increased gradually between the two groups were significantly different(P>0. 05). Pearson’s test showed that the expression of expression SLR and LEP exists a significant negative correlation (R= -0. 949,P<0. 01). Conclusion Progesterone may influence the ex-pression of ADAM10,SLR and LEP by the regulation of leptin to participate GDM occurs.