Objective To investigate the mechanism of inter fe ron-? (IFN?) in preventing hepatic fibrosis in rat experimental model . Methods Thirty-six male Sprague-Dawley rats were divide d into three groups randomly: group A(normal controls)of 12 rats were given norm al food and water and received subcutaneous injection of peanut oil twice weekly ; group B (fibrotic model)and group C (IFN? prevention) with 12 rats in eac h were induced by carbon terrachloride, high cholesterol and low protein. Group C were treated with intramusclular injections of IFN? in saline, administered daily at the doses of 1?10 5U. At the end of the sixth week, all the rats in each group were killed, the liver function was examined and the samples of t he liver obtained by biopsy were submitted to histological liver fibrosis studie s. The expressions of ?-smooth muscle actin in hepatic tissues were detect ed with immunohistochemical methods. The effect of IFN? on apoptosis of hep atic stellate cells (HSC) were investigated under electron microscope. Results The level of hepatic collagen Ⅰand Ⅲ and serum PC Ⅲ, HA, and LN in group C was significantly lower than that of group B under lig ht microscope (P

0 05). The positive rate of HbeAg (35 7%) in multiple group was significantly lower than in single group ( P 0 05) However, the incidences of premature rupture of membrane (PROM), premature delivery, 28 1%,25 0% fetal distress and newborn infant asphyxia 31 3%,25 0% in multiple hepatitis virus infection group were significantly higher than in single hepatitis virus infection group ( P

Objective To explore the clinical guiding value of spiral computed tomography(SCT)with three-dimensional computed tomography reconstruction(3-DCT)in percutaneous kyphoplasty(PKP).Methods 24 patients prepared to be treated with PKP were examined under 3-DCT before the treatment.Results According to the contra-indications shown by 3-DCT,11 patients' operation were cancelled;the others were treated with PKP and got good outcomes due to the accurate data provided by 3-DCT.Conclusion SCT plays an important role in PKP.

The difference of gene expression profile changes in Barrett's esophagus (BE) and cardia intestinal metaplasia (CIM) epithelium was studied and the novel associated genes were screened in the early stage by cDNA microarray. The cDNA retro-transcribed from equal quantity mRNA from BE and CIM epithelial tissues were labeled with Cy3 and Cy5 fluorescence as probes. The mixed probe was hybridized with three pieces BiostarH-40s double dot human whole gene chip. The chips were scanned with a ScanArray 4000. The acquired images were analyzed using GenePix Pro 3.0 software. It was found a total of 141 genes were screened out that exhibited differentially expression more than 2 times in all three chips. It was identified that in gene expression profiles of BE, 74 genes were up-regulated and 67 down-regulated as compared with CIM. The comparison between the difference of gene expression profile changes in BE and CIM epithelia revealed that there existed the difference between BE and CIM at gene level. 141 genes with the expression more than two time were probably related to the occurrence and development of BE and the promotion or progress in adenocarcinoma.

Bilingual teaching is a positive exploration of raising high quality talented persons under the new situation.It exists some problems in local college bilingual teaching such as the shortage of teachers,standard teaching materials,proper students level,management measures and so on.Local colleges should strengthen training the teachers,vigorously introduce the talented persons;do well the bilingual teaching material construction through many ways,teach students in accordance with their aptitude, standardize management and establish the scientific teaching appraisal mechanism.

Objective To study the protein conformational change of placenta tissue by using Raman spectrum.Methods By using Raman spectroanalysis,we detected the placenta protein conformational change of GDM and control groups.Results(1)In the placenta of GDM,the absorption bands of tryptophan and phenylalanine were increased obviously.(2)In the placenta of GDM,the secondary structure of protein was composed of α-helix,random coil and β-sheet.Conclusions In the placenta of GDM,the orderly conformations of main chains in protein are decreased.Side chains of amino acids,especially tryptophan and phenyl-alanine,are changed greatly.The structure variation of protein may be correlated to the diabetic complications.

Noun and verb are always two primary lexical knowledge information in all kinds of languages. It plays an important role in the structure and function of the language. Cognitive activation and differential neural basis when aphasiacs distinguish from these two kinds of lexical knowledge information is the focus of subjects, such as neuropsychology, neurolinguistics and neuroimage. The specific deficit regarding the precessing of noun and verb was analyzed in the article with the data of this aphasiac.

ObjectiveTo investigate the characteristic of aphasia after left Basal ganglia injured.Methods10 cases with focus at left Basal ganglia and aphasia were assessed with Chinese Rehabilitation Research Center's Chinese Standard Aphasia Examination 12 weeks after stroke.Results and ConclusionThe characteristics of these 10 patients did not only show similar to the characteristics of Basal ganglia aphasia,but some other features.The relationship of the symptom and imaging finding has been discussed.

Since the symptoms and mechanism of poststroke aphasia are various and complicated, there are a great deal of problems which are difficult to resolve yet. At the aspect of aphasia research, Chinese and Western medicine have different emphases, Chinese medicine emphasizes particularly on therapy, Western medicine emphasizes on discussing mechanism of aphasia, all kinds of sorts and evaluation of aphasia and pertinence rehabilitation, and so on; modern research methods include neurolinguistics, neuropsychology, cognitive science, neurorehabilitation, neuroelectrophysiology, neuroimage and so on, all these means of aphasia research often involve in cross multi-subject, furthermore becoming powerful implement of recognizing brain mechanism.

The method of preparation of a Milk Substitute, formula 5410, and its nutritive value on rats have been reported in previous communications. Further tests of its nutritive effect were made by feeding a group of 100 infants including 4 premature and 10 undernourished. Another group of 43 infants fed with human breast milk or cow's milk were observed during the same period as controls. Among the infants of the two groups there were 6 pairs of twins; one of each pair was fed with the Milk Substitute and the other with human or cow's milk. Great majority of the infants were cared by their own mothers whose cooperation had been secured, while the rest of the infants (10%) were kept in our nursery.The Milk Substitute feeding was started with infants between half and six months of age, with an average age of three months. Observations were continued until they all reached one year old. Fish liver oil and ascorbic acid were supplied to infants of both the experimental and the control groups. Vegetable soup and fruit juice were given to the infants before five months of age. Then various kinds of other foods, including rice porridge, wheat flour nudols, bread, crackers, mashed meat and vegetable and egg yolk were individually supplemented furnishing not more than 1/3 of the total caloric intake, (at the age of one year), as the family income permitted.The appetite of the experimental infants was normal. There was no digestive disturbances and abnormal frequency and appearance of the stool. The average daily caloric intake was similar to those recorded in the literature.The body weight and height of the babies in the experimental group fell well within the normal range. The average initial body weight and height of the infants in the experimental group were somewhat lower than those of the control; however, the height reached .that of the control at the age of 7 months, and the weight at about 11 months. The red blood cell counts and the hemoglobin value of the blood were normal.Values of blood alkaline phosphatase activity higher than 15 Bodansky units were shown in 20 babies of the experimental group (27%) and 8 babies of the control group (23%) at the beginning of the observation; only 4 babies in the experimental group were found abnormal high blood alkaline phosphatase value at the end. At the beginning, 3 cases of rickets and 3 cases of suspected rickets were indicated by the radiograph of the wrist bones of the babies in the experimental group, and only one suspected ricket in the control group were observed; and they all became normal at the end of the experiment. Besides, there were no other signs of any nutritional deficiency among all the infants.