3.Remodeling of inflammatory periodontal tissues during orthodontic tooth movement
Jun ZHU ; Hongyi ZHAO ; Miao HE ; Jie YING
Chinese Journal of Tissue Engineering Research 2010;14(33):6262-6266
BACKGROUND: More and more patients with periodontal disease require orthodontic treatments. Thus, the remodeling process and its mechanism of inflammatory periodontal tissues become a hot point during orthodontic tooth movement.OBJECTIVE: To observe the remodeling of inflammatory periodontal tissues during orthodontic tooth movement.METHODS: A total of 50 Sprague Dawley rats were randomly divided into the control and periodontitis groups. In the periodontitis group, rats were established periodontitis models. After that, all rats were prepared for orthodontic tooth movement models. The remodeling of periodontal tissues was observed by hematoxylin-eosin staining at 1, 3, 5, 7 and 14 days after orthodontic tooth movement.RESULTS AND CONCLUSION: The movement distance of the periodontitis group was greater than that of the control group. At 0-7 days after orthodontic force application, there was obviously bone resorption at the pressure side and the bone formation was inhibited at the tension side; at 14 days after force application, the bone resorption was diminished, associated with large numbers of multinucleated osteoclasts at the pressure sides in both groups. The findings showed that rats with periodontitis suffered more periodontal traumatism during orthodontic tooth movement, thus, treatment should be delayed until the inflammatory signs were controlled and the local inflammatory was eliminated.
4.Antibacterial Activity Observation of TGC, MH and PB on the Pan-resistant Acinetobacter Baumannii in Vitro
Hua ZHANG ; Jie ZHAN ; Jinrong CANG ; Zi FU ; Qiaodi GUI ; Ying LIU ; Miao CHEN ; Yanyan GONG
Journal of Modern Laboratory Medicine 2015;(4):93-95
Objective To observe tigecycline (TGC),minocycline (MH)and polymyxin B (PB)in vitro antibacterial activity of pan-resistant Acinetobacter baumannii (PDR-Ab)for clinical treatment,provide the basis for infection control.Methods Collected 76 patients’clinical specimens used for no repeat count of isolation and identification with pan-resistant Acineto-bacter baumannii in Shaanxi Provincial People’s Hospital from October 2013 to March 2013.Used tigecycline,minocycline and polymyxin B to do susceptibility testing with disk diffusion method (KB).Results 76 pan-resistant Acinetobacter bau-mannii ,sensitive to the rate for tigecycline and polymyxin B were 100% sensitivity rate of minocycline and intermediary rates were 67.11%,27.63%.Conclusion Tigecycline,minocycline and polymyxin B for the Pan-resistant Acinetobacter bau-mannii had good in vitro antibacterial activity.It provide a reference for clinical pan-resistant Acinetobacter baumannii infec-tions caused by diseases treatment.
5.Analysis of trace element levels in maternal blood of pregnant women according to different pregnancy and ages of pregnant women in Xuzhou area
Jinming ZHU ; Ying CHU ; Qingrong WU ; Jie LIU ; Min LI ; Miao HE ; Fengyun PENG
The Journal of Practical Medicine 2016;32(20):3380-3382
Objective To investigate the levels of trace element in calcium, magnesium, zinc, iron and copper in maternal blood of pregnant women of different pregnancy and ages of pregnant women , and its relation to the pregnancy the age of pregnant women. Methods Calcium, magnesium, zinc, iron and copper in serum in 10 131 cases of pregnant women (3 565 cases in the first pregnancy, 6 566 cases in second pregnancy) were measured. All cases (both first pregnancy and second pregnancy) were analysed according to three age periods (less than or equal to 25, 25 to 35 years old, more than or equal to 35). Results (1)Comparing to the cases in second pregnancy, Copper in serum of the cases in first pregnancy was lower, while zinc, magnesium and iron were higher (P < 0.05). But the level of calcium had no difference (P > 0.05). (2) For the cases in the first pregnancy in different age periods, all 5 kinds of trace elements were compared. Only the zinc level in serum in the groups of 25 ~ 35 years old and more than or equal to 35 years old was higher than that in the group of less than or equal to 25 years old (P < 0.05). No difference was found in the rest of trace elements in different age groups (P > 0.05). (3) For the cases in the first pregnancy in different age stages , all 5 kinds of trace elements were compared basis on the age periods. the zinc and iron levels in serum in the groups of 25 to 35 years and more than or equal to 35 years old were higher than those in less than or equal to 25 years old (P < 0.05). No difference (P > 0.05) was found in the other three kinds of trace elements in different age periods. Conclusions (1)There are differences in trace elements, magnesium, zinc, iron and copper, and no difference in calcium in the first and second pregnancy. (2)Trace elements in serum of pregnant women in different age periods are different. (3)According to the characteristics of various trace elements in serum of pregnant women of different pregnancy and age periods, trace elements shall be supplemented to meet the needs of the pregnant women and fetus.
6.Evaluation of the 80 mm volume shuttle CT cerebral perfusion imaging and 4D-CT angiography in patients with stenosis or occlusion of internal carotid artery
Xin SUI ; Jie LU ; Runcheng LI ; Miao ZHANG ; Xiangying DU ; Yanxiang CAO ; Wei ZHANG ; Ying GUO ; Yun SHEN
Chinese Journal of Radiology 2010;44(3):249-254
Objective To evaluate the 80 mm volume shuttle cerebral CT perfusion(CTP) and 4D-CT angiography (CTA) in patients with stenosis or occlusion in Willis circle.Methods Conventional cerebral plain CT, 80 mm CTP and dynamic 4D-CTA were performed in 55 patients with unilateral MCA/ ICA stenosis or occlusion.The parameter maps of cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT) and time to peak (TTP) were analyzed.Meanwhile dynamic 4D-CTA images were also obtained.The significance of the differences of CBF, CBV, MTT and TTP between the affected side and the contralateral side was assessed using K Independent Samples analysis.Results In 40 patients with unilateral stenosis or occlusion of MCA/ICA, CTP was found abnormal in 36 patients.MTT and TTP of affected side [(7.18 ±1.34), (19.65 ±1.81) s] were significantly prolonged compared to contralateral side [(5.22±1.14) s, (17.62±1.65) s, X~2 =30.833,25.817, P<0.017].Centrum ovale or parietal lobe ischemic lesions were observed in 16 patients on CTP.In 15 patients with bilateral stenosis or occlusion of MCA/ICA, CTP was observed abnormal in 10 patients.CBF, CBV, MTT and TTP of affected side [(42.85 ±6.09) ml·100 g~(-1)·min~(-1), (2.63 ±0.42) ml·100 g~(-1), (11.27 ±1.43) s, (21.07 ±1.44) s)] were significantly different from those of contralateral side [(71.20 ±6.30) ml·100 g~(-1)·min~(-1), (2.29 ±0.15) ml·100 g~(-1), (3.38 ±0.61) s, (17.64 ±1.70) s (X~2 =17.314, 5.913,17.334,13.834,P<0.017)].On 4D-CTA covering 80 mm (0.625 mm×l28), unilateral stenosis of MCA were observed in 22 patients (13 right MCA and 9 left MCA), unilateral occlusion were observed in 5 patients (1 right MCA and 4 left MCA) and bilateral MCA stenosis/occlusion were observed in 9 patients.4D-CTA covering Willis cycle can display stenosis/occlsion of MCA as same as conventional CTA and DSA.Conclusion 80 mm volume shuttle CTP and 4D-CTA provide valuable information about the hemodynamic changes and the abnormalities of intracranial artery in patients with MCA/ICA stenosis or occlusion.
7.Comparison of TB-IGRA and Protein Chip in the Diagnosis of Mycobacterium Tuberculosis
Qiaodi GUI ; Ke LIU ; Jinrong CANG ; Yanyan GONG ; Ying LIU ; Miao CHEN ; Yan LI ; Jie SONG ; Jiankang REN
Journal of Modern Laboratory Medicine 2014;(5):114-116
Objective To evaluate the advantages of TB-IGRA and protein chip to detect the Mycobacterium tuberculosis. Methods From October 2013 to March 2014,collected 78 cases of clinical diagnosis of tuberculosis and normal control’s pe-ripheral blood specimens,used TB-IGRA kits and Mycobacteriumtuberculosis IgG kit(protein chip)to detected respectively. The results were analyzed and compared.Results The sensitivity of protein chip and TB-IGRA in the detection of Mycobac-teriumtuberculosis were 34.5% and 89.7% respectively,which was statistically significant (χ2=26.95,P<0.05).The spe-cificity of protein chip and TB-IGRA were 90.0%,95.0% respectively,which were not statistically significant (χ2=1.64,P> 0.05).The positive rate of TB-IGRA and Protein chip in tuberculosis were 90.5% and 42.9%.The positive rate of TB-IGRA and Protein chipin extrapulmonary tuberculosis were 89.20% and 29.7% respectively.Conclusion Compared TB-IGRA and protein chip,either diagnose tuberculosis or extrapulmonary tuberculosis has highly positive rate and sensitivity, TB-IGRA can be widely used in the early screening of tuberculosis.
8.Experience of Finland children's whole-course health care service and management and its enlightenment
Miao YANG ; Xiang-yong WU ; Jie-chun GAO ; Guo-ying HUANG
Shanghai Journal of Preventive Medicine 2021;33(1):79-
Finland is acknowledged as an international leader in the children's health care by the World Health Organization, especially in the formulation and planning of children's health care policies. In the article, we introduces Finnish service mode and management experience in the whole-process medical care for children, including successful operation of hierarchical diagnosis and treatment, key role of public health nurses in the whole-process management, significant influence of social and family environment on the healthy development of children, and integration of children's health and welfare services through multi-sectoral cooperation. We make some suggestions and recommendations for the construction of children's health service capacity in China in strengthening the laws and policies in the children's health, improving the network construction and three-level connection of maternal and child health care system, taking the construction of pediatric integrated health care system as the breakthrough point to further promote hierarchical diagnosis and treatment, improving the multi-sectoral cooperation mechanism, and maximizing the influence of information technology and family.
9.Value of multi-slice spiral CT in the diagnosis of closed thyroid cartilage injury
Xiao-Yi FANG ; Zhen-Long LI ; Su-Miao CHEN ; Ying-Jie ZHAO
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2008;43(6):424-427
Objective To explore the clinical application and to evaluate the value of multi-slice spiral computed tomography (MSCT) in closed thyroid cartilage injury.Methods MSCT Scan was performed in 5 patients with closed thyroid cartilage injury,and 2D and 3D images reconstructions were achieved after volumn data was transferred to workstation.Results In 5 cases,the thyroid cartilage fracturewas found in left board in 4 patients.in right board in 1 patient.In addition.one patient had concurrent cricoid cartilage fracture and another patient had laryngotracheal stenosis.These fractures and changes were all visualized by 2D and 3D images.Lower window level and window width were helpful to reveal the structures of thyroid cartilage.Multi-planar reconstruction (MPR) Was superior in displaying alignment and displacement of fracture in 4 cases.3D-volume reconstruction (3D-VR) was accurate in displaying space change of cartilage structures.In 3 cases,the evaluation of 3D-VR was accurate in assessing the length,width and shape of fracture,providing helpful data for the clinician to adopt the optimal management.Computed tomography virtual laryngoscope (CTVL) helped to offer the criterions to the diagnosis of upper airway stricture and the location of laryngotraeheal stenosis in one case.Conclusions MSCT was useful in the diagnosis and management of closed thyroid cartilage injury and the laryngotracheal stenosis.It was believed that the reasonable use of the reprocessing technique plays an important role in the diagnosis,treatment and evaluation of the effect of closed thyroid cartilage injury.
10.The effects of sexually transmitted infections (STI)/AIDS behavioral intervention among female sex workers.
Ying-Jie LIU ; Hai-Feng DING ; Miao YU
Chinese Journal of Preventive Medicine 2007;41(6):492-495
OBJECTIVETo explore the effective sexually transmitted infections (STI)/AIDS intervention strategies among female sex workers at the metropolis areas with low prevalence.
METHODSA comprehensive intervention was carried out among female sex workers in eight recreation establishments which have representative characters in Chaoyang district, and the effects of intervention was subsequently evaluated by a questionnaire from September 2005 to February 2006. The data were analyzed by SPSS11.5.
RESULTSThe study subjects aged 17-40 year old (25.22 +/- 5.81), and 203 (89. 82%) of them had high or middle school education background. 166 were unmarried, and 205 (90.70%) had no job, and 244 (99. 12%) subjects were migrants. After intervention, the correct answer rates for the knowledge of STI/ AIDS rose from 52.6% to 75.4% (chi2 = 22.701, P < 0.01); and the correct use of condom were higher than those of baseline, with the rise from 22.12% to 34.76% (chi2 = 8.14, P < 0.05).
CONCLUSIONThe STI/AIDS comprehensive intervention measures were effective and should be evaluated and generalized in the similar metropolis regions.
Acquired Immunodeficiency Syndrome ; epidemiology ; prevention & control ; Adolescent ; Adult ; China ; Female ; Humans ; Male ; Risk Reduction Behavior ; Sex Work ; Sexually Transmitted Diseases ; epidemiology ; prevention & control ; Surveys and Questionnaires ; Young Adult