2.Analysis of risk factors for deep venous thrombosis of lower limbs after laparoscopic surgery
Feng CHEN ; Ying CAI ; Wenjun LI
Journal of Xinxiang Medical College 2017;34(9):833-835
Objective To investigate the risk factors for deep vein thrombosis (DVT) of lower limbs after laparoscopic surgery.Methods A total of 230 patients underwent laparoscopic surgery were selected in Huanggang Central Hospital from January 2014 to August 2016.The patients were divided into DVT group and non-DVT group according to DVT of the lower limbs,and the related risk factors for DVT of lower limbs after laparoscopic surgery were analyzed.Results In the 230 patients,there were 10 patients with DVT of lower limbs and 220 patients without DVT of lower limbs,the incidence of DVT of lower limbs was 4.35% (10/230).Logistic regression analysis showed that age ≥40 years old,operation time ≥120 min,postoperative ambulation time ≥ 30 h,the intraoperative position of high-head and low-foot,plasma D-Dimer level ≥0.5 mg · L-1 were the independent risk factors for DVT of lower limbs after laparoscopic surgery (P < 0.05).Conclusion There is a certain incidence of DVT of the lower limbs after laparoscopic surgery.The effective prevention measures should be taken to reduce the incidence of DVT after laparoscopic surgery according to the related factors of DVT.
3.Analysing ultrasonography imaging outcomes of intravenous leiomyomatosis
Chinese Journal of Ultrasonography 2003;0(12):-
Objective To investigate ultrasonography imaging feature of intravenous leiomyomatosis (IVL).Methods Analysing 34 cases of IVL retrospectively,which had been treated and diagnosed in the hospital from Jan,1998 to Dec,2003.Results Among 34 cases,2 cases were diagnosed as IVL,20 cases were diagnosed as uterine leiomyoma or uterine leiomyoma with degeneration and 12 cases as uterine leiomyoma with adenomyosis.Conclusions Knowledge shortage on the clinical feature of IVL causes the low rate of accurate diagnosis of IVL by ultrasonography imaging.
5.Clinical effects of modified Sugiura surgical operation on the portal hypertension in 30 patients
Xi FANG ; Jinzhan LI ; Ying LI ; Chudong CAI
Chinese Journal of Primary Medicine and Pharmacy 2009;16(1):71-72
Objective To explore the clinical curative effect of the modified Sugiura surgieal operation on the portal hypertension. Methods Look back of sex analysis the Sugiura surgical operation of 30 enforcement im-provement to cure a door the disease sufferer's clinical data of the vein high pressure. Results Measure a free door vein pressure(FPP) respectively in the Sugiura operation: slice before the Pi FPP for (3.06±0.39) kPa, slice after the Pi FPP for (3.07±0.32) kPa, leave to break after the surgical operation FPP for (3.22±0.31) kPa, showed difference(P <0.01) very much with slice before the Pi after slicing Pi,but with leave to break surgieal iperation be-hind do not show difference(P > 0.05). 2 earlier period appear the liver brain disease.27 patients 3 ~ 6 eclipse of the moon tube basic disappearance of the varixes after the surgical operation, die in cirrhosis after a surgical operation bad for 16 months change. There are 25 sufferers with visit for 3 years,2 appear again to bleed up the digest way and the forward didn't discover the liver brain patient's. Conclusion Improve the Sugiura surgical operation cures the dis-ease more ideal valid surgical operation type of a vein high pressure,long-term after can lower surgical iperafion again the issue of blood rate,varix relapse the attack source of vitality rate of rate and liver brain.
6.Analysis of Narcotic Drug Use from 2002 to 2005 in Our Hospital
Ying ZHENG ; Yixian LI ; Yu ZHENG ; Li ZHENG ; Guangmi CAI
China Pharmacy 1991;0(06):-
OBJECTIVE: To evaluate the current situation and trend of narcotic drug use in our hospital where the authors work in order to provide the reference for scientific management and rational use of these drugs. METHODS: The yearly amount of narcotic drugs administered in the whole hospital, the yearly amount in the separate departments, as well as drug expenditures and ratios between January 2002 and November 2005 were added up and analyzed statistically. RESULTS: The amount of bucinnazine use dominated in the first. The amount of morphine for oral use was increasing year by year. The amount of fentangl transdernal patch use was also bigger and increasing rapidly. However, the amount of pethidine and morphine for injection use was decreasing. CONCLUSION:Analgetics for oral and transdermal use will be the main categories of analgetics in the future.
7.Survey on current status of humanistic care among medical students in clinical practice in obstetrics and gynecology department
Ying ZHANG ; Mian HE ; Yubin LI ; Jianbo YANG ; Jian CAI
Chinese Journal of Medical Education Research 2012;11(8):866-868
Objective To explore the current status of humanistic care among medical students in clinical practice in obstetrics and gynecology department and its related influencing factors and to propose the corresponding countermeasures.Methods Scale of humanistic care quality was used in the survey for clinical practice students in obstetrics and gynecology department.ResultsThe total score rate of human care quality of medical students before clinical teaching were (84.12 ± 9.24)with a scoring rate of 72%.Significant differences were observed in the medical students with different medical professional(P <0.05).The total score of humanistic care quality of medical students after clinical teaching were (96.41 ± 1 1.53 ),significant higher than that of before training ( P < 0.05 ).ConclusionHumanistic care quality in medical students needs to be strengthen.Clinical training in obstetrics and gynecology department combined with humanities education has important practical significance to improve the quality of medical students.
8.Study of the brain glucose metabolism in different stage of mixed-type multiple system atrophy
Ying WANG ; Benshu ZHANG ; Li CAI ; Meiyun ZHANG ; Shuo GAO
Chinese Journal of Nuclear Medicine and Molecular Imaging 2014;34(1):14-18
Objective To investigate the brain glucose metabolism in different stage of mixed-type multiple system atrophy (MSA).Methods Forty-six MSA patients with cerebellar or Parkinsonian symptoms and 18 healthy controls with similar age as patients were included.According to the disease duration,the patients were divided into three groups: group 1 (≤ 12 months,n=14),group 2 (13-24 months,n=13),group 3 (≥ 25 months,n =19).All patients and controls underwent 18F-FDG PET/CT brain imaging.To compare metabolic distributions between different groups,SPM 8 software and two-sample t test were used for image data analysis.When P<0.005,the result was considered statistically significant.Results At the level of P<0.005,the hypometabolism in group 1 (all t>3.49) was identified in the frontal lobe,lateral temporal lobe,insula lobe,anterior cingulate cortex,caudate nucleus and anterior cerebellar hemisphere.The regions of hypometabolism extended to posterolateral putamen and part of posterior cerebellar hemisphere in group 2 (all t>3.21).In group 3,the whole parts of putamen and cerebellar hemisphere were involved as hypometabolism (all t>4.08).In addition to the hypometabolism regions,there were also stabled hypermetabolism regions mainly in the parietal lobe,medial temporal lobe and the thalamus in all patient groups (all t>3.27 in group 1,all t>3.02 in group 2,all t>3.30 in group 3).Conclusions Disease duration is closely related to the FDG metabolism in the MSA patients.Frontal lobe,lateral temporal lobe,anterior cingulate cortex and caudate nucleus can be involved at early stage of the disease.Putaminal hypometabolism begins in its posterolateral part.Cerebellar hypometabolism occurs early at its anterior part.Besides,thalamus shows hypermetabolism in the whole duration.18F-FDG metabolic changes of brain can reflect the development of mixed-type MSA.
9.Analysis of the relationship between the postgastrectomy cholelithiasis and gastrectomy
Xi FANG ; Chudong CAI ; Ying LI ; Junshuo ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2009;16(7):1223-1224
Objective To explore the factors for the development of gallstones after gastrectomy. Methods 52 cases of patients with postgastrectumy,were retrospectively analyzed according to their diseases for gastrectomy and operation form. Results Incidence of gallstone in patients of postgastrectomy was higher than in general population. Among which, Billroth Ⅱ type of gastrectomy for carcinoma was the highest (35.5%), then the total gastrectomy (31.5%) and proximate gastrectomy(13.5%). Billroth Ⅰ type operation was 10.3%. Incidence of gallstone in pa-tients of selective vagotomy was lowest (2.5%). Condusion Billroth Ⅱ type of gastrectomy and total gastrectomy were the risk factors of postgastrectomy cholelithiasis. The causes for gallstone formation after Billroth Ⅱ type of gas-trectomy were the restitution of digestive canal and metabolic disorder of bile acid.
10.Effects of angiotensin Ⅱ on NF-κB binding activity in alveolar macrophage
Ying MENG ; Xu LI ; Shaoxi CAI ; Gaosu ZHOU
Chinese Journal of Emergency Medicine 2009;18(5):471-474
Objective To determine the effects of angiotensin Ⅱ (Ang Ⅱ) on NF-κB DNA binding activity in alveolar macrophage. Method Human alveolar macrophages were isolated and made homogeneous from alveo-lar lavage fluid, and cuhtured in DMEM. Alvcolar macrophages were treated with AugⅡ (10-6M) for 15 min, 30 min, 60 min and 120 min, respectively. Moreover, alveolar macmphages were pretreated with irbesartan (AngⅡ type 1 receptor blocker) for Ⅰ hour before stimulated with Angiotensin Ⅱ for Ⅰ hour. Electrophoretic gel mobility shift assay (EMSA) was used to detect NF-κB DNA binding activity. The protein expression of IκBα was examined by Western blot. Expressions of TNF-α and ICAM-1 mRNA were detected by using RT-PCR. Results EMSA re-vealed that there was a increase in up-regulation of NF-κB DNA binding activity after alveolar macrophages were treated with Ang Ⅱ for 15 rain and peaked at 60 min. Irbesartan treatment reduced DNA binding activity. Com-pared with control group, the protein expression of IκBα decreased in Ang Ⅱ treatment group(0.29±0.11, P= 0.013), and Irbesartan treatment significantly increased protein expression of IκBα(0.83±0.12, P=0.001). The expressions of TNF-α and ICAM-1 mRNA were up-regulated by AngⅡ in comparison with the control group (TNF-α:1.13±0.17 vs. 0.42±0.099; ICAM-1 0.55±0.08 vs. 0.16±0.050, P=0.003). Irbesartan inhibited the expressions of TNF-α (0.77±0.15 vs 1.13±0.17, P=0.02; ICAM-1(0.32±0.07 vs 0.55±0.08, P =0.001). Conclusions Ang Ⅱ is capable to stimulate NF-κB signal pathway in alveolar macrophages.