1.Analysing ultrasonography imaging outcomes of intravenous leiomyomatosis
Chinese Journal of Ultrasonography 2003;0(12):-
Objective To investigate ultrasonography imaging feature of intravenous leiomyomatosis (IVL).Methods Analysing 34 cases of IVL retrospectively,which had been treated and diagnosed in the hospital from Jan,1998 to Dec,2003.Results Among 34 cases,2 cases were diagnosed as IVL,20 cases were diagnosed as uterine leiomyoma or uterine leiomyoma with degeneration and 12 cases as uterine leiomyoma with adenomyosis.Conclusions Knowledge shortage on the clinical feature of IVL causes the low rate of accurate diagnosis of IVL by ultrasonography imaging.
3.Analysis of risk factors for deep venous thrombosis of lower limbs after laparoscopic surgery
Feng CHEN ; Ying CAI ; Wenjun LI
Journal of Xinxiang Medical College 2017;34(9):833-835
Objective To investigate the risk factors for deep vein thrombosis (DVT) of lower limbs after laparoscopic surgery.Methods A total of 230 patients underwent laparoscopic surgery were selected in Huanggang Central Hospital from January 2014 to August 2016.The patients were divided into DVT group and non-DVT group according to DVT of the lower limbs,and the related risk factors for DVT of lower limbs after laparoscopic surgery were analyzed.Results In the 230 patients,there were 10 patients with DVT of lower limbs and 220 patients without DVT of lower limbs,the incidence of DVT of lower limbs was 4.35% (10/230).Logistic regression analysis showed that age ≥40 years old,operation time ≥120 min,postoperative ambulation time ≥ 30 h,the intraoperative position of high-head and low-foot,plasma D-Dimer level ≥0.5 mg · L-1 were the independent risk factors for DVT of lower limbs after laparoscopic surgery (P < 0.05).Conclusion There is a certain incidence of DVT of the lower limbs after laparoscopic surgery.The effective prevention measures should be taken to reduce the incidence of DVT after laparoscopic surgery according to the related factors of DVT.
5.Clinical effects of modified Sugiura surgical operation on the portal hypertension in 30 patients
Xi FANG ; Jinzhan LI ; Ying LI ; Chudong CAI
Chinese Journal of Primary Medicine and Pharmacy 2009;16(1):71-72
Objective To explore the clinical curative effect of the modified Sugiura surgieal operation on the portal hypertension. Methods Look back of sex analysis the Sugiura surgical operation of 30 enforcement im-provement to cure a door the disease sufferer's clinical data of the vein high pressure. Results Measure a free door vein pressure(FPP) respectively in the Sugiura operation: slice before the Pi FPP for (3.06±0.39) kPa, slice after the Pi FPP for (3.07±0.32) kPa, leave to break after the surgical operation FPP for (3.22±0.31) kPa, showed difference(P <0.01) very much with slice before the Pi after slicing Pi,but with leave to break surgieal iperation be-hind do not show difference(P > 0.05). 2 earlier period appear the liver brain disease.27 patients 3 ~ 6 eclipse of the moon tube basic disappearance of the varixes after the surgical operation, die in cirrhosis after a surgical operation bad for 16 months change. There are 25 sufferers with visit for 3 years,2 appear again to bleed up the digest way and the forward didn't discover the liver brain patient's. Conclusion Improve the Sugiura surgical operation cures the dis-ease more ideal valid surgical operation type of a vein high pressure,long-term after can lower surgical iperafion again the issue of blood rate,varix relapse the attack source of vitality rate of rate and liver brain.
6.Analysis of Narcotic Drug Use from 2002 to 2005 in Our Hospital
Ying ZHENG ; Yixian LI ; Yu ZHENG ; Li ZHENG ; Guangmi CAI
China Pharmacy 1991;0(06):-
OBJECTIVE: To evaluate the current situation and trend of narcotic drug use in our hospital where the authors work in order to provide the reference for scientific management and rational use of these drugs. METHODS: The yearly amount of narcotic drugs administered in the whole hospital, the yearly amount in the separate departments, as well as drug expenditures and ratios between January 2002 and November 2005 were added up and analyzed statistically. RESULTS: The amount of bucinnazine use dominated in the first. The amount of morphine for oral use was increasing year by year. The amount of fentangl transdernal patch use was also bigger and increasing rapidly. However, the amount of pethidine and morphine for injection use was decreasing. CONCLUSION:Analgetics for oral and transdermal use will be the main categories of analgetics in the future.
7.Preparation Technology Optimization of Salicylic Acid Drop Pills
Na HUANG ; Yingying FENG ; Ying CAI ; Sidong LI ; Mingneng LIAO
China Pharmacist 2016;19(6):1200-1202
Objective:To study the influencing factors in the preparation of salicylic acid dropping pills , and determine the opti-mum preparation process .Methods: The environmental factors , heating temperature , matrix ratio and preparation steps of salicylic acid drop pills were observed .With pill weight difference , dissolution time and appearance quality as the indices , an orthogonal test was adopted to optimize the preparation process .Results:Salicylic acid and the matrix should be separately heated to prevent red ox-ide.The optimized preparation process of drop pills was as follows:the ratio of PEG 400 and PEG 6000 was 1∶5, the temperature of drug solution was 50℃, the dropping distance was 8 cm and the dropping rate was 70 drops per minute .Conclusion:The preparation process is simple and practicable .The pill weight difference , dissolution time and appearance quality all meet the quality require-ments.
8.Effects of exercises on the lipid metabolism and expression of PPAR-α mRNA in skeletal muscles of ApoE knockout mice
Wenliang ZHANG ; Ying CAI ; Kangling XIE ; Jian LI ; Suixin LIU
Chinese Journal of Physical Medicine and Rehabilitation 2014;36(12):897-901
Objective To observe the influence of exercises on the mRNA expression of peroxisome proliferator-activated receptor (PPAR-α) and its target genes of acyl-CoA oxidase (ACO),Enoyl-CoA-hydratase and 3-hydroxyacyl-CoA-dehydrogenase (EHHADH) in the skeletal muscles in insulin-resistance mice to develop a way to improve the lipid metabolism.Methods Twenty male ApoE knockout mice were randomly divided into two groups,the high-fat diet group (group HFD) and the exercise training group (group Ex).The HFD group were fed with highfat diet,while the Ex group were fed in the same way,with additionally swimming training.And ten healthy male C57BL/6j mice were chosen as the control group(group ND).After 12 weeks of intervention,the serum lipid,blood glucose and insulin levels were determined,and homeostasis model assessment insulin resistance index (Homa-IRI) was calculated.The bilateral gastrocnemiuses were cut to be observed under a transmission electron microscope,and the mRNA expression of PPAR-α,ACO and EHHADH in skeletal muscle were measured using reverse transcription polymerase chain reaction(RT-PCR).Results The transmission electron microscope showed that the sarcolemma edema,mitochondrial swelling,as well as focal myocytolysis and edema within myofibrils were observed in the HFD group.The total cholesterol,low-density lipoprotein cholesterol,free fatty acid,fasting glucose,insulin and HomaIRI of the HFD group were significantly higher than the control group (P < 0.05),while the mRNA expression of PPAR-α,ACO and EHHADH was significantly deceased than the latter(P < 0.05).After swimming,the abovementioned pathological changes disappeared.The serum lipid of the Ex group were significantly lower (P < 0.05),while HDL was significantly higher (P < 0.05).And fasting insulin,glucose and HOMA-IR of the Ex group were significantly lower (P < 0.05),while the mRNA expression of the above in the Ex group were significantly increased (P <0.05).Conclusion Swimming training could improve insulin resistance and metabolic disorder of lipid of ApoE knockout mice.The possible mechanisms may be through up-regulating the expression of PPAR-α,which in turn stimulates the expression of ACO and EHHADH mRNA to strengthen fatty acid β-oxidation.
9.Application of automated four-dimensional volume color Doppler ultrasonography in normal fetal heart screening
Ying ZHANG ; Ailu CAI ; Ting LI ; Yili ZHAO
Chinese Journal of Medical Imaging Technology 2009;25(7):1273-1275
Objective To assess the application of automated four-dimensional (4D) volume color Doppler ultrasonography in normal fetal heart screening. Methods Four-dimensional volume color Doppler was acquired at the level of four chamber view level in 120 fetuses from 18 to 23 weeks of gestation. Three diagnostic planes including color Doppler information were retrieved by automated multiplanar imaging from the 4D volumes. The left ventricular outflow view (cardiac plane 1), the right ventricular outflow view (cardiac plane 2) and ductal arch view (cardiac plane 3) were acquired. Tomographic ultrasound imaging (TUI) was added to display all the three diagnostic planes. The data were then analyzed to determine whether cardiac planes 1-3 were displayed correctly in each volume. Results Automated 4D volume color Doppler ultrasonography displaying rate of cardiac plane 1, cardiac plane 2, cardiac plane 3 were 100%, 96.67% and 91.67%, respectively. Cardiac plane 1 was displayed at least three TUI plane, cardiac plane 2 was displayed at least two TUI plane, and cardiac plane 3 was displayed at least two TUI plane. Conclusion It is possible to acquire important planes of the fetal heart with automated 4D volume color Doppler ultrasonography and the visualization rate of the three diagnostic planes is fine.
10.Value of 18F-FDG PET/CT in differentiating tuberculous and cancerous diffuse peritoneal lesions
Wenyan ZHANG ; Li CAI ; Ying WANG ; Haonan YU ; Shuo GAO
Tianjin Medical Journal 2017;45(2):220-224
Objective To study the 18F-FDG PET/CT features of tuberculous and malignant diffuse peritoneal lesions and to discuss the diagnostic value of 18F-FDG PET/CT in diagnosing and differentiating the lesions. Methods The 18F-FDG PET/CT features of 72 patients with tuberculous peritonitis,28 primary serous papillary carcinoma of the peritoneum and 135 peritoneal metastases confirmed by clinic and/or histopathology, were retrospectively reviewed. The peritoneal thickening features of tuberculous and malignant peritoneal lesions were observed. The maximal standardized uptake value (SUVmax) of peritoneal lesions and ascites, ascites SUVmax/liver SUVmax (T/NT) were compared between tuberculous peritonitis and cancerous peritonitis. The ROC curve was used to analyze the diagnostic efficiency of T/NT, SUVmax of peritoneal lesions and ascites. Results The typical 18F-FDG PET/CT features of tuberculous peritonitis were uniformity thickening of parietal peritoneum, mesenteric and omental stain like changes, widely and even distribution of the peritoneal 18F-FDG, while the cancerous peritonitis was obvious uneven thickening of parietal peritoneum, mesenteric and omental nodules and pie-shape changes, uneven distribution of the peritoneal 18F-FDG. The degree of 18F-FDG uptake was increased in all peritoneal lesions, and there was no significant difference between the tuberculous group (SUVmax=10.53±5.44) and the cancerous group (SUVmax=11.45±6.78, t=1.017, P>0.05). The 18F-FDG concentration in malignant ascites (SUVmax=1.88±0.65,T/NT=0.73± 0.18) was obvious higher than that of tuberculous ascites (SUVmax=1.67±0.69,T/NT=0.57±0.27, t=2.243 and 5.045,both P<0.05). The area under the ROC curve of T/NT, SUVmax of ascites, SUVmax of peritoneal lesions were 0.707, 0.593, 0.536, respectively. Conclusion The 18F-FDG PET/CT imaging can reflect the morphology and metabolic changes of peritoneal lesions. It is important to combine the SUVmax of ascites in order to improve the efficiency of diagnosing the diffuse peritoneal diseases.