1.Absorption of Radioiodinated Nerve Growth Factor in Hypoxic Neonatal Rats Brain
Journal of Applied Clinical Pediatrics 2004;0(11):-
Objective To observe absorption of exogenous nerve growth factor(NGF) between normal newborn rats and newborn rats with hypoxidosis.Methods Thirty-two healthy newborn rats(7 days of age) were divided into experiment group and normal group.Experiment rats were made into hypoxic-ischemic brain damage(HIBD) model.NGF labeled with()~(125)I or()~(125)I was injected into the rats abdominant.All of the rats were killed and brain was removed after 30 minutes.The brain was dissected into basal forebrain,forehead cortex,hippocampus,thalamus,cerebellum,smellorb,pituitary tissue samples were assayed for radioactivity in a two-channel gamma counter.Results Absorptions of two groups(()~(125)I-NGF) were significantly higher than those of()~(125)I in basal forebrain,cortex,hippocampus,cerebellum.Absorptions of hypoxic group were significantly higher than those of control group in cortex,hippocampus,cerebellum.Conclusions NGF can penertrate blood brain barrier of newborn rats into brain regions by means of peripheral administration.Early application of NGF for treating hypoxic-ischemic encephalopathy(HIE) is feasible.
2.Microglia in brain metastasis tumor
Journal of International Oncology 2012;39(7):513-515
Microglia(MG)is recognized as the main immune effector in central nervous system injury and disease.MG can regulate the tumorigenesis and development of brain metastases tumor(BMT)by different ways.Studing the roles and mechanisms of MG in BMT will provide new insights into the prevention and treatment of BMT.
3.Evaluation on rationality of curriculum of AIDS and drug abuse and its teaching quality
Chinese Journal of Medical Education Research 2013;(4):328-331
Objective To evaluate the teaching quality of AIDS and drug abuse and to provide evidences for teaching improvement.Methods Quantitative research and qualitative research was combined.Questionnaire including evaluation of curriculum,teachers and teaching quality was conducted among 273 students majored in anesthesiology and clinical medicine (2006 grade) as well as in forensic medicine,laboratory and stomatology (2008 grade) in quantitative research.Observation and indepth interview were used in qualitative research to observe the teaching process and receive students'feedback.Information about students' evaluation criterions and attitude toward teachers were collected by qualitative research.Chi-square test and descriptive statistic were used with SPSS 13.0.Results 90.8% students thought this lesson was necessary and important and the contents were accepted by them.24.2% students expected increasing study hours and having practice classes.Evaluation of course time,contents and importance were different by students of different majors.Average scores of students' evaluation on teachers' quality,teaching contents and teaching methods were 25.2,22.4,11.0,respectively.Three aspects of teaching methods got the lowest scores:vivid (2.71 points out of 3.0 points),interaction (2.71 points out of 3.0 points) and flexibility (2.72 out of 3.0 points).Interview results demonstrated that students have diversified demand for teaching methods and expect to increase practice lessons and multimedia teaching as well as to effective communicate between teaching and learning.Conclusions Course of AIDS and drug abuse is accepted by students.As a whole,students are basically satisfied with teachers,however,teachers and related sectors should pay more attention to teaching method improvement and teaching skill enhancement.
4.Cultivation of medical English majors' translation competence under the framework of eco-translatology
Chinese Journal of Medical Education Research 2014;(3):294-297
The accelerating pace of exchanges and cooperation in medical field between China and foreign countries demands a large number of medical papers, medical-related materials to be ac-curately translated into multiple languages , especially between English and Chinese . Oriented at English majors (medicine directed), based on eco-translatory approach and student-centered teaching method by creating simulations of the medical English ecological translation environment, this paper provided a better and effective practice-based teaching idea, which can promote students' medical English translation competence and strategies, even cultural consciousness and pragmatic ability in a comprehensive manner.
5.Research of sexual cognitive status for college students in Luzhou area
Chongqing Medicine 2014;(19):2464-2466
Objective To study the the current situation of sexual for college students in luzhou area and to provide basis for their sexual health education .Methods 2 226 college students from four colleges in luzhou area were investigated by stratified clus-ter sampling method ,SPSS11 .5 software was used to analysis the results .Results 59 .62% of the students′knowledge was mainly from the media ,the test for sexual knowledge of college students′was satisfactory ;58 .94% of college students would like to com-municate and communication about sex and love ,84 .61% of the students thought that college students should have correct love and chastity view ,82 .95% of the students thought that should make efforts to prevent venereal disease and AIDS ,55 .27% of the students were firmly opposed to marriy during school study ;75 .15% of the students were firmly opposed to premarital sexual be-havior ,44 .44% of the students minded that lover once had sex ,36 .56% of the students broken up immediately when found that loveer had sex before .Conclusion The college students′sexual maturity in advance but knowledge of sex education relative lag , making them for many sexual problems and phenomena ,so scientific and systematic sexual health education should be strengthen in students .
6.Progression of paclitaxel in the chemotherapy of advanced esophageal cancer
Cancer Research and Clinic 2011;23(10):715-718
Recently,paclitaxel has been used as a new agent on patients with advanced esophageal cancer,and several studies have demonstrated that paclitaxel and paclitaxel-based regimens have significant activity in patients with advanced esophageal cancer and showed highly response rates than the combination of 5-fluorouracil (5-Fu) and cisplatin.However,there have been some problems which need to be solved such as drug-resistance,side effect,and so forth.The new medicament form of paclitaxel can not only depress poison without anti-allergy but also raise medicament curative effect as well as the pharmacal concentration.Although most of the research on the new medicament form of paclitaxel are still limited in the stage of laboratory,it has possessed potential advance in the treatment of advanced esophageal cancer.
7.Clinical application of helical tomotherapy in tumor therapy
Journal of International Oncology 2010;37(11):828-831
Helical tomotherapy is the radiation treatment device that combined CT imaging with a linear accelerator, and capable of implementing 360-degree intensity modulated radiation therapy (IMRT), MVCT image guidance, adaptive therapy, stereotactic radio-surgery (SRS) and stereotactic body radiation treatment (SBRT) etc. A very broad spectrum of tumor can be treated by helical tomotherapy.
8.The effects of self-value on personality
Chinese Journal of Tissue Engineering Research 2002;6(19):2983-
This article try to illustrate the relationship of self value and personality by paraphrasing these two concepts,and deduce the effects of self value to personality from this.This article also point out the questions how to direct and help university students to set proper self value and then modle healthy personality.It bring forward supposition of the resolvement of the questions.On the base of the demonstrative research we carry out a validative research.
9.Comparison of the Drug Price Administration Models Among Different Developed Countries
China Pharmacy 1991;0(01):-
OBJECTIVE:To study the drug price administration models in some developed countries,so as to provide ref?erence information for establishing drug price administration model in China.METHODS:The comparative method and crite?rion method were adopted to study the published literature.RESULTS&CONCLUSION:Although different countries have carried out different models,they still have similarity in some policies.Therefore,we should pay attention to learn the advan?tages in different drug administration models.
10.A clinical study of interventional therapy for liver metastases from colorectal carcinoma
Journal of Interventional Radiology 2001;0(06):-
Objective To evaluate the efficacy and prognostic factors in patients with liver metastases from colorectal carcinoma treated by interventional therapy.Methods Follow up information of 80 patients with liver metastases from colorectal carcinoma were analyzed. The survival time and parameters were likely to affect the prognosis revealed by statistical methods. Results It was shown that the over all 0.5,1,2,3year survival rates were 100%,75.8%, 31.5% and 10.8% respectively. Univariate analysis showed that the age, the volume ratio of the tumors/liver, abundance of the tumor vessels, the retention of the lipiodol, resection of the original lesion and the difference of the tumor sizes between pre therapy and post therapy were the significant prognostic factors. Multivariate analysis showed that abundance of the tumor vessels and the difference of the tumor sizes between pre therapy and post therapy were the most significant factors. Conclusions The hepatic arterial infusion chemotherapy and embolization are effective to patients with liver metastases from colorectal carcinoma proportionately to the tumor vascular abundance and primary lesion resection.