Pathology diagnosis plays an important role in clinical medical activities but we have to face the plight of the scarcity of the pathological physicians in China.The curriculum structure in forensic science for undergraduates is almost equivalent to clinical medicine for undergraduates.However,the study of forensic pathology course makes the undergraduates' starting point of pathology of forensic science higher than that of clinical medical undergraduates.From the training experience of forensic pathologists and clinical pathologists' mutual exchange and cooperation in developed countries,we proposed that forensic undergraduates participate in the physician qualification examination as similar professional qualification and participate in the hospital standardized training of pathological physicians residents and apply for graduate professional degree education of clinical pathology to alleviate the shortage of clinical pathologists.

Autophagy is associated with the occurrence,development and drug resistance of ovarian cancer,which has become a hot topic in ovarian cancer.Many scholars believe that cancer is closely associated with tumor suppressor genes,and some tumor suppressor genes are related to autophagy.This article will review the effects of tumor suppressor genes on ovarian cancer through autophagy at home and abroad,which provides the reference for clinical research.

Physical factor therapy is commonly used in the treatment of nervous system damage. Recent years, physical factor therapy gets popular attention because of its good therapeutic effects, low cost, simple operation and widely application. This article respectively in-troduced the effects of electrical stimulation therapy, functional magnetic stimulation therapy and biofeedback therapy on neurogenic blad-der.

Objective To investigate effect of hs-CRP,IL-6, TNF-αand ICAM-1 in patients with coronary heart disease by Guanxinshengmaiyin. Methods 120 patients with coronary heart disease were selected and randomly divided into two groups.60 cases in control group were treated by routine treatment, 60 cases in experiment group were on the base of control group with Guanxinshengmaiyin,1 month for a course.hs-CRP, IL-6, TNF-αand ICAM-1 levels, clinical efficacy, electrocardiogram ( ECG ) and adverse reactions were compared after treatment.Results Compared with before treatment, hs-CRP, IL-6, TNF-αand ICAM-1 levels were lower(P<0.05).Compared with control group, the serum hs-CRP, IL-6, TNF-αand ICAM-1 levels were lower ( P<0.05 ) , the total efficiency ( 80.00%) was higher ( P<0.05 ) , the depth of T wave of lead II and lead III were lower (P<0.05),the adverse reactions occur rate was lower(P<0.05).Conclusion Guanxinshengmaiyin can reduce serum hs-CRP, IL-6, TNF-αand ICAM-1 levels in patients with coronary heart disease, and has good clinical curative effect, less adverse reaction.

Objective To characterize the changes of motor nerve conduction velocity (MCV) and F wave in patients with definite amyotrophic lateral sclerosis (DALS) as related to the duration and severity of the disease. Methods A total of 46 patients with DALS were recruited for the ALS group and 35 healthy adults for the control group. MCV and F wave were examined with median, ulnar, tibial and peroneal nerves in all the patients and compared with those in the controls. Results It was found that the distal motor latencies (DML) and MCV of the median, ulnar, tibial and peroneal profundus nerves in the ALS group were all significantly delayed as compared to those in the control group. The F wave occurrence frequency was lower, the central latencies as well as its side-to-side difference of the F wave in the 4 nerves were significantly longer in the ALS group than those in the control group. For those with more severe conditions, their central latencies of F wave and DML in the 4 nerves of ALS patients were significantly longer, and the MCV were significantly slower than those with milder conditions. A 3-year of follow-up of the patient revealed that there were progressive delay in DML and F wave central latencies, as well as a progressive decrease in MCV or CAMP amplitude. Conclusion The duration and severity of ALS has significant effects on the MCV and F wave of nerves in the upper and lower limbs. MCV and F wave can be used as valuable electrodiagnostic tools for DALS.

This article summarized the mechanism of traditional Chinese medicine treatment for lung cancer in recent years. Related literatures were from the immune regulation, inhibiting growth and metastasis of lung cancer cells and promoting apoptosis and reversing drug resistance. Review showed that traditional Chinese integrated with western medicine for lung cancer has gradually become the consensus of clinical practioners.

Transcranial direct current stimulation is one of the non-invasive brain-stimulation techniques. Based on the introduction of the origin and development, this article gave an overview of the mechanisms emphatically, the current view is that the transcranial direct current stimulation may exert effect on neuromodulation by changing cortical excitability, increasing synaptic plasticity, impacting cortical excitation/ inhibition balance, altering regional cerebral blood flow, modulating the activity within and between different cortical networks. In this review, clinical studies and analysis findings were compared, and then 2 problems should be discussed for ideal effects: choice of stimulating parameters and timing of the stimulation in relation to task performance.

Acidosis ; complications ; physiopathology ; Animals ; Aorta, Thoracic ; drug effects ; physiopathology ; Dopamine ; pharmacology ; In Vitro Techniques ; Male ; Rats ; Rats, Wistar ; Shock, Septic ; complications ; physiopathology ; Sympathomimetics ; pharmacology

Animals ; Aorta, Thoracic ; physiology ; Dopamine ; pharmacology ; Hydrogen-Ion Concentration ; In Vitro Techniques ; Rats ; Vasoconstriction ; drug effects