Objective To study the efficacy of complete hemihepatic vascular exclusion (CHVE) in the prevention of tumour dissemination during liver resection for hepatocellular carcinoma (HCC).MethodsA case-control study was carried out on 281 patients who underwent liver resection for HCC between February 2006 and April 2010.89 patients underwent hepatic resection using CHVE (group A) and 192 using Pringle maneuver (group B).The postoperative 1-,2-,3 year rates of intrahepatic recurrence and lung metastasis,and the overall disease-free survivals were compared between the two groups.ResultsThe incidence of lung metastasis at 1 year after operation was significantly lower in group A than group B (6.7％ vs.15.1％,P=0.048).There were no signilicant differences in the incidences of lung metastasis at postoperative year 2 and 3 between the two groups (15.7％ vs.25.0％ and 32.6％ vs.30.7％ ; P＞0.05).The differences in the postoperative 1-,2-,3- year intrahepatic recurrence rates were not significant between the two groups (20.2％ vs.31.8％,51.7％ vs.60.3％,68.5％ vs.79.2％,respectively; P＞0.05).The median survivals of the two groups were 25.9 months and 21.7 months,respectively.Patients in group A had a significantly higher overall disease-free survival rate than patients in group B (P=0.035).ConclusionsCHVE was efficacious in reducing the incidence of lung metastasis and in improving the overall disease-free survival in patients after liver resection for HCC.CHVE contributed in preventing intraoperative tumour dissemination and in improving prognosis.

Objective To observe the effect of Chinese Medicines with the function of antioxidation on lupus nephritis(LN)pa- tients.Methods The 25 LN patients consisting of renal function normal group(15 cases)and renal failure group(10 cases)were treated with Huang Qi(Radix Hedysari)and Shu Dihuang(Radix Rehmanniae Praeparata)as main ingredients for 6 months in suc- cession.Changes of symptom,systemic lupus erythematosus disease activity index(SLEDAI),activity index(AI),lipid peroxide (LPO),superoxide dismutase(SOD),glutathione peroxide(GSH-Px),malondialchehyche(MDA),nitric oxide(NO),blood and urine routine examination,24-hour urine protein quantity,liver and kidney function,anti-double-stranded DNA(anti ds-DNA),complement 3(C_3)and complement 4(C_4),after treatment were observed.Results SLEDAI and AI scores were remarkably different from those before treatment(P

0.05).After the contamination,the mice body weight of high dose group of cypermethrin and dehamethrin were lower than the negative control group (P

Background Based on prior research in the field, a preliminary questionnaire was created to compare the coping strategies of schizophrenic patients to those of non-ill community residents. Results of the comparison were subsequently used to develop a questionnaire suitable for use in schizophrenic patients.Methods Ninety-one of the 92 items in the preliminary questionnaire were identified from previous questionnaires, and one additional item was created based on information provided in individual interviews with schizophrenic patients. This questionnaire was administered to 315 community controls and 208 schizophrenic inpatients. Exploratory Factor Analyses to identify the factor structure of coping strategies were independently conducted for controls and patients. Based on these results, a revised 65-item instrument was developed and administered to a new group of 287 controls and 219 schizophrenic inpatients. Confirmatory Factor Analyses (CFA) using Linear Structural Relations (LISREL) were independently conducted for the two groups to confirm their respective factor structures.Results Six coping categories identified in normal controls were problem solving, avoidance, cognitive adjustment, emotional adjustment, seeking special support, and denial. Among schizophrenic patients, however,coping strategies of "seeking special support" and "denial" were not independent of the other four coping categories. Their items were distributed among the others. Results of CFA confirmed this four-category model of coping strategies for schizophrenic patients.Conclusions Coping categories employed by schizophrenic patients were different from those employed by normal community controls. Schizophrenic patients lacked the necessary flexibility of selecting appropriate coping strategies.

Alcoholism ; therapy ; Humans ; Methanol ; poisoning

Carbamates ; analysis ; Fruit ; chemistry ; Organophosphorus Compounds ; analysis ; Pesticide Residues ; analysis ; Vegetables ; chemistry

Objective: To obtain a strain which has stronger antagonistic effect against Streptococcus mutans(S. mutans), and then to study the antagonistic effect of the fermentation filtrate of the strains. Method:Surface soil samples were harvested and used in an in vitro bacteria culture system for screening of antagonistic strains against Streptococcus mutans. Ferment filtrate of the strains was respectively prepared and the antagonism of the filtrate against S. mutans was examined.Result:A strain with strong restrain effect on Streptococcus mutans was found and was identified to be Bacillus licheniformis. The strain was named strain 1#. At pH 7.0, 150 r/min and constant temperature of 30 ℃ cultivated for 24 hours,the antagonistic energy of ferment filtrate was 1 500 IU/ml,the ferment filtrate showed strong heat stability, at 37 ℃ for 1 hour, the activity decreased by 35%; at 60 ℃ for 30 min, by 47%, for 1 h, by 50%, at 100 ℃,the activity maintained 39%.The optimum pH for the activity of the ferment filtrate was 7.0, at pH 3.0, the activity kept 70% and at pH 11.0, 65%.Conclusion:The fermentation filtrate of strain 1# of Bacillus licheniformis is antagonistic against S. mutans.

Objective To understand the situation of benzene series compounds pollution inside some Passenger cars in Tangshan and provide data for the formulation of corresponding countermeasures for the prevention and control of the pollution. Methods One hundred and twenty-two cars used for different periods of time were selected from March, 2009 to May, 2009 and the concentrations of benzene,toluene and xylene were determined.At the same time the basic situation (car type, date of manufacture) was investigated with questionnaire. Results The disqualified rate of benzene, toluene, xylene were 14.8%(18/122), 26.2%(32/122) and 20.5%(25/122) respectively. Eighty-one cars did not meet the standard, accounting for 66.4 %(81/122). The median of benzene, toluene, xylene in the cars used within six months were 0.086, 0.900, 0.400 mg/m3 respectively. The exceeded rate of benzene, toluene, xylene inside the cars which were used for not more than six months were 28.6%(10/35), 57.1%(20/35), 60.0%(21/35) respectively. The concentrations of benzene series compounds decreased gradually later on. The concentrations of benzene inside the cars with adsorbent were lower, the concentrations of toluene inside the highgrade cars were higher and the concentrations of xylene inside the cars with leather seats was higher. Conclusion Benzene, toluene, xylene pollution inside cars has been showed in this investigation in Tangshan. The concentrations of benzene series compounds are associated with using time, adsorbent, car grade and the seat material.

Objective To investigate the association of rs10004195 single nucleotide polymorphisms in Toll like re-ceptor 10(TLR 10) gene with helicobacter pylori infection and associated diseases. Methods A total of 652 pa-tients who has been examined by gastroscopy were obtained, and then peripheral blood samples were collected from all the patients. Immune colloidal gold method was used to test the serological Hp antibody of all the patients. The TLR10 gene rs10004195 polymorphisms were examined by direct DNA sequencing of the PCR products. Results The frequencies of AA,TT and AT genotype on TLR10 rs10004195 were 30. 98%, 20. 71%, 48. 31%;there was significant difference between Hp antibody positive group and Hp antibody negative group in the TT frequencies of TLR10 rs10004195 ( P<0. 05 ) . No significant difference between controls and Hp associated diseases groups in Hp antibody positive group or in Hp antibody negative group were observed. Conclusion There was correlation be-tween the TLR10 rs10004195 loci genotype and the risk of Hp infection, but no correlation with Hp associated dis-eases.