1.The role of complete hemihepatic vascular exclusion in the prevention of tumour dissemination during hepatectomy
Chinese Journal of Hepatobiliary Surgery 2012;18(7):512-514
Objective To study the efficacy of complete hemihepatic vascular exclusion (CHVE) in the prevention of tumour dissemination during liver resection for hepatocellular carcinoma (HCC).MethodsA case-control study was carried out on 281 patients who underwent liver resection for HCC between February 2006 and April 2010.89 patients underwent hepatic resection using CHVE (group A) and 192 using Pringle maneuver (group B).The postoperative 1-,2-,3 year rates of intrahepatic recurrence and lung metastasis,and the overall disease-free survivals were compared between the two groups.ResultsThe incidence of lung metastasis at 1 year after operation was significantly lower in group A than group B (6.7% vs.15.1%,P=0.048).There were no signilicant differences in the incidences of lung metastasis at postoperative year 2 and 3 between the two groups (15.7% vs.25.0% and 32.6% vs.30.7% ; P>0.05).The differences in the postoperative 1-,2-,3- year intrahepatic recurrence rates were not significant between the two groups (20.2% vs.31.8%,51.7% vs.60.3%,68.5% vs.79.2%,respectively; P>0.05).The median survivals of the two groups were 25.9 months and 21.7 months,respectively.Patients in group A had a significantly higher overall disease-free survival rate than patients in group B (P=0.035).ConclusionsCHVE was efficacious in reducing the incidence of lung metastasis and in improving the overall disease-free survival in patients after liver resection for HCC.CHVE contributed in preventing intraoperative tumour dissemination and in improving prognosis.
2.Effect of Cypermethrin and Deltamethrin on DNA Damage in Lymphocytes in Male Mice
Journal of Environment and Health 2007;0(08):-
0.05).After the contamination,the mice body weight of high dose group of cypermethrin and dehamethrin were lower than the negative control group (P
3.Clinical Observation on 25 Cases of Lupus Nephritis Treated by Chinese Medicines with the Function of Antioxidation
Journal of Traditional Chinese Medicine 1993;0(05):-
Objective To observe the effect of Chinese Medicines with the function of antioxidation on lupus nephritis(LN)pa- tients.Methods The 25 LN patients consisting of renal function normal group(15 cases)and renal failure group(10 cases)were treated with Huang Qi(Radix Hedysari)and Shu Dihuang(Radix Rehmanniae Praeparata)as main ingredients for 6 months in suc- cession.Changes of symptom,systemic lupus erythematosus disease activity index(SLEDAI),activity index(AI),lipid peroxide (LPO),superoxide dismutase(SOD),glutathione peroxide(GSH-Px),malondialchehyche(MDA),nitric oxide(NO),blood and urine routine examination,24-hour urine protein quantity,liver and kidney function,anti-double-stranded DNA(anti ds-DNA),complement 3(C_3)and complement 4(C_4),after treatment were observed.Results SLEDAI and AI scores were remarkably different from those before treatment(P
5.The factor structure of coping strategies in schizophrenic patients
Yongsheng TONG ; Dengfeng WANG ; Ying CAO
Chinese Journal of Nervous and Mental Diseases 2006;32(5):385-391
Background Based on prior research in the field, a preliminary questionnaire was created to compare the coping strategies of schizophrenic patients to those of non-ill community residents. Results of the comparison were subsequently used to develop a questionnaire suitable for use in schizophrenic patients.Methods Ninety-one of the 92 items in the preliminary questionnaire were identified from previous questionnaires, and one additional item was created based on information provided in individual interviews with schizophrenic patients. This questionnaire was administered to 315 community controls and 208 schizophrenic inpatients. Exploratory Factor Analyses to identify the factor structure of coping strategies were independently conducted for controls and patients. Based on these results, a revised 65-item instrument was developed and administered to a new group of 287 controls and 219 schizophrenic inpatients. Confirmatory Factor Analyses (CFA) using Linear Structural Relations (LISREL) were independently conducted for the two groups to confirm their respective factor structures.Results Six coping categories identified in normal controls were problem solving, avoidance, cognitive adjustment, emotional adjustment, seeking special support, and denial. Among schizophrenic patients, however,coping strategies of "seeking special support" and "denial" were not independent of the other four coping categories. Their items were distributed among the others. Results of CFA confirmed this four-category model of coping strategies for schizophrenic patients.Conclusions Coping categories employed by schizophrenic patients were different from those employed by normal community controls. Schizophrenic patients lacked the necessary flexibility of selecting appropriate coping strategies.
6.Relevant research of occurrence and severity of alcoholic liver diseases
Jing TONG ; Ying WANG ; Bingyuan WANG
Journal of Chinese Physician 2013;(2):156-158
Objective To investigate the disease occurrence-related factors and severity of alcoholic hepatitis (AH) and alcoholic liver cirrhosis (ALC).Methods According to the clinical diagnostic criteria that were passed by the 2010 Chinese Society of Fatty Liver Hepatology and alcoholic liver disease study group,the clinical data of 241 AH and ALC patients were analyzed.Results The amount of liquor taken daily,the time limit of drinking,and total amount of liquor taken in ALC patients were significantly different from those in AH patients (P <0.01),respectively.In ALC patients,the proportion (48.39%)of workers,peasants,and unemployed low-income alcoholics was significantly higher than that (25.58%)in AH patients (P <0.01).Laboratory tests showed the AST/ALT ratio in the ALC group (2.63 ±4.74)was significantly higher than that in the AH group (1.01 ±0.52) (P <0.01); TG [(1.33±1.24)mmol/L] and cholesterol (CHOL) [(3.14 ± 1.25) mmol/L] in ALC group were significantly lower than TG [(2.29 ± 1.60)mmol/L] and CHOL [(4.27 ±0.79)mmol/L] in the AH group (P <0.01).Conclusions Alcoholic liver disease occurrence and severity were related to the amount of liquor taken,the time limit of drinking,and the work ; AST/ALT ratio,TG and CHOL values were consistent with the severity of alcoholic liver disease.
7.Problems about On-line Pharmacy Development in China
Lingquan MENG ; Ying ZHOU ; Xiao TONG
China Pharmacy 2005;0(16):-
OBJECTIVE: To explore the development channel of on-line pharmacy in China. METHODS: The problems existing in the individual customers and the retail chain pharmaceutical enterprises were analyzed. RESULTS & CONCLUSIONS: The relation between the individual customers and the retail chain pharmaceutical enterprises should be coordinated when developing the on-line pharmacy. Only when the problmes such as the psychology and habbits of individual customers, and the running cost, drug safe distribution, network development and so on in the retail chain pharmaceutical enterprises have been solved can the on-line pharmacy smoothly developed.
8.Screen of antagonistic strains against Streptococcus mutans and investigation of the curb activity of ferment filtrate
Ying LIU ; Jing ZHANG ; Mingyou TONG
Journal of Practical Stomatology 2001;0(01):-
Objective: To obtain a strain which has stronger antagonistic effect against Streptococcus mutans(S. mutans), and then to study the antagonistic effect of the fermentation filtrate of the strains. Method:Surface soil samples were harvested and used in an in vitro bacteria culture system for screening of antagonistic strains against Streptococcus mutans. Ferment filtrate of the strains was respectively prepared and the antagonism of the filtrate against S. mutans was examined.Result:A strain with strong restrain effect on Streptococcus mutans was found and was identified to be Bacillus licheniformis. The strain was named strain 1#. At pH 7.0, 150 r/min and constant temperature of 30 ℃ cultivated for 24 hours,the antagonistic energy of ferment filtrate was 1 500 IU/ml,the ferment filtrate showed strong heat stability, at 37 ℃ for 1 hour, the activity decreased by 35%; at 60 ℃ for 30 min, by 47%, for 1 h, by 50%, at 100 ℃,the activity maintained 39%.The optimum pH for the activity of the ferment filtrate was 7.0, at pH 3.0, the activity kept 70% and at pH 11.0, 65%.Conclusion:The fermentation filtrate of strain 1# of Bacillus licheniformis is antagonistic against S. mutans.
9.Clinical observation of the prevention of pressure ulcers in malignant tumor patients with forced position by Resina Draconis
Qunqiu TONG ; Yiwen YING ; Yinqiao CHEN
Chinese Journal of Primary Medicine and Pharmacy 2017;24(7):992-995
Objective To explore the precaution efficacy of Resina Draconis for pressure ulcers in malignant tumor patients with forced position.Methods According to digital table method,168 malignant tumor patients with forced position were randomly divided into observation group and control group.Furthermore,the control group accepted the basic nursing,the observation group accepted the basic nursing and the Resina Draconis packed in bone-like parts.Afterwards,the patients' local skins were observed at intervals,and the incidence rates of pressure sores were compared between the two groups.Results The incidence rate of pressure ulcers of the observation group was 3.57%,which of the control group was 11.90%,the difference between the two groups was statistically significant (x2 =4.085,P =0.043).Conclusion Application of Resina Draconis can prevent pressure sores in malignant tumor patients with forced position.
10.Clinical study on the recovery of wrist joint function after radical distal fracture by combined stasis elimination and powder intervention
Yan LI ; Yongjun TONG ; Ying CHEN
Chinese Journal of Biochemical Pharmaceutics 2017;37(6):81-83
Objective To study the clinical study of the effect of removing blood stasis and eliminating powder on the recovery of wrist function after distal radius fracture.MethodsA total of 82 patients with distal radius fractures were selected from September 2012 to October 2016.The random number table method was divided into study group and control group.The two groups were given intervention, and the study group (VAS score), the correlation index(swelling time, pain time, fracture healing time), clinical curative effect and the recovery of wrist function were observed and compared with the two groups.ResultsAfter treatment, the VAS scores of the two groups were significantly lower than those before treatment, and the VAS scores of the study group were significantly lower than those of the control group (P<0.05).After the treatment group, the swelling time, pain time (P<0.05).After treatment, the total effective rate was 87.80% higher than that of the control group (68.29%) (P<0.05).After treatment, the two groups were significantly higher than those in the control group (P<0.05), and the wrist function scores of the study group were significantly lower than those of the control group (P<0.05).ConclusionThe combined effect of removing blood stasis and eliminating powder is effective in the treatment of distal radius fractures, which can effectively reduce the pain and reduce the healing time of the fracture and promote the recovery of the wrist function.