Objective To analyze the diagnostic methods and etiological factors in patients with fever of unknown origin (FUO).Methods The clinical data of 358 patients with FUO,Who were treated in hospital since February 2001 to April 2005,were retrospectively analyzed.Results Among the 358 patients,312 patients were definitely agnosed(87.2%),A- mong the 312 definitely diagnosis patients,172 cases were infectious disease(132 cases were bacterial infection,31 cases were virus infection,6 eases were fungus infection and 3 cases belonged to other disese),143 cases were bacterial were non-infections disease(66 cases were collagen vascular diseases,63 cases were malignant tumor and 14 cases belonged to other disese).46 cases remained origin-unknown until they were discharged from hospital.Conclusion In the diag- nosis of FUO,We should manage to collect oathogenic,immunologic and pathologic evidences.Infectious diseases,collagen vascular diseases and malignant tumors are the main causes of FUO.

Objective To compare the clinical results of endodontic mandibular first molar by different restoration methods.Methods From January 2011 to February 2013,96 patients in our hospital dental visits with 110 defective teeth who accepted the dental restoration were randomly selected in this clinical research.The repairing of defective teeth were divided into 3 groups randomly:36 were fabricated with CAD/CAM zirconia all -ceramic crowns,35 were CAD/CAMzirconia all -ceramic onlays,39 were direct filling and repairing with composite resins. The clinical effects of 3 groups were evaluated and compared at baseline,and 1,6,12 months after restoration using modified USPHS criteria.The results were analyzed statistically by SPSS 13.0.Results It was not found that 110 defective teeth were debonded at 12 months after restoration.There were significant differences in assessment results of secondary caries,marginal fitness,appearance and color matching at 12 months after restoration by different restoration methods (χ2 =6.705,7.768,6.910,11.624,all P <0.05).Conclusion The dental restorations with CAD/CAMzirconia all -ceramic crowns and CAD/CAM zirconia all -ceramic onlays show satisfactory clinical performance in short time.

Blood Volume ; Child ; Edema ; etiology ; therapy ; Evidence-Based Medicine ; Hemofiltration ; methods ; Humans ; Nephrotic Syndrome ; complications ; therapy ; Renal Dialysis ; methods ; Severity of Illness Index

Child ; Chronic Disease ; Humans ; Kidney Diseases ; therapy ; Kidney Failure, Chronic ; therapy ; Nutritional Support ; Renal Insufficiency, Chronic ; therapy

Coronary Stenosis ; diagnostic imaging ; Humans ; Ultrasonography, Interventional ; methods

Objective To observe the clinical efficacy of traditional Chinese medicine fumigation in treating ankylosing spondylitis (AS). Methods Sixty patients were divided into fumigation group (30 cases) and non-fumigation group (30 cases), the treatment course was 20 days. The changes of finger pitch, pillow away from the wall, hip flexion, hip extension of the patients and the impact of fumigation on acute inflammation (ESR, CRP) were observed. Enzyme-linked immunosorbent assay was used to determine serum TNF-? and IL-10 before and after treatment to observe the effect of fumigation treatment on inflammatory cytokine expression. Results The total effective rate of treatment group was 90.0% and control group was 83.3%. The efficiency rate of the treatment group was 66.6% and control group was 33.3%. After treatment, finger pitch, pillow away from the wall, hip flexion, hip extension of the treatment group were better than before treatment, the difference was significant. ESR, CRP and TNF-?, IL-10 of the treatment group were significantly decreased compared with the control group (P

Integrin ?V?3, one of the major members of the integrin family, plays a pivotal role in tumor angiogenesis because it mediates the cell-extracellular matrix and cell to cell adhesion as well as controls cells proliferation, differentiation, cellular modality and motility.Due to restricted high-expressions in tumors, integrin ?V?3, is considered a suitable targeting receptor for tumor diagnosis.In the past decade, several molecular imaging tracers for integrin ?V?3, have been used to noninvasively visualize its expression in tumor tissues and angiogenic blood vessels through the usage of nuclear imaging, nuclear magnetic resonance imaging, ultrasound, and optical imaging.Noninvasive detection of integrin ?V?3, expression can potentially be used for tumor diagnosis and prognosis.The current imaging probes used to target integrin ?V?3, through usage of different technologies are briefly recapitulated in this review.

Objective To observe the therapeutic effect of herbal fumigation and steaming for rheumatoid arthritis(RA) and to explore its anti-inflammation mechanism.Methods Twenty-two RA patients were randomized into two groups: group A(N=10) received meloxican and methotrexate,and group B(N=12) received herbal fumigation and steaming of Xunzheng Prescription(mainly composed of Rhizoma et Radix Notopterygii,Radix Angelicae Pubescentis,Radix Saposhnikoviae,Ramulus Cinnamomi,Herba Asari,Rhizoma Chuanxiong,Caulis Piperis Kadsurae,Radix Cynanchi Paniculati,Rhizoma Curcumae Longae,Lignum Sappan,Borneolum Syntheticum) additionally.The treatment lasted 20 days.The changes of joint symptoms and signs,erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP) were observed before and after treatment.Serum tumornecrosis factor ?(TNF-?) and intercellular adhesion molecule 1(ICAM-1) contents were detected by enzymelinked immunoassay.Results Compared with group A,joint pain and tenderness index as well as morning stiffness time were improved in group B (P

Objective To study traditional Chinese herb fumigation and steaming in treating AA model rats and the change of IL-1? in serum and joint, and explore its mechanism. Method Fifty Wistar rats were randomly divided into normal group, model group, aqua group, high dose group, low dose group. Except normal group and the right foot of rats were injected CFA 0.1 mL to make AA model. Aqua group, high dose group and low dose group received steam treatment for 10 days. In the 21st day, the content of IL-1? in serum and the expression level in joint were detected. Results Traditional Chinese herb fumigation and steaming group had notable reduction the IL-1? content in serum and strong positive expression of IL-1? in joint than model group. Conclusion Traditional Chinese herb fumigation and steaming can down-regulate the level of IL-1? in serum and restrain IL-1? expression in joint.

60 year) were recruited for this study and tested with " Fuling "(poris cocos),which is rich in insoluble fibers. Fuling (50g per day),in the form of steamed bun,was given to each subject twice a day(breakfast and supper) for seven days.Fasting and postprandial blood glucose were measured before and after the study.Results:The fasting blood glucose levels before and after the study were 8 76?2 04mmol/L and 7 94?1 45mmol/L,respectively ( ?s , P