1.The Development of Xeno-transplantation and Medical Ethical Reflection
Chinese Medical Ethics 1995;0(03):-
The basic research and development of xeno-transplantation technique has been a new field. The article analyzed its current situation and problems, discussed the ethical problems the researchers and physicians faced, and raised a series of ethical principles which should be obeyed in xeno-transplantation, that is: stick to combining humanism and utilitarianism; observe the technological and sanitary criterion, choose the graft cautiously; Be attentive and loyal to the recipient's health; no harm and beneficial to the humankind. Besides, the article explored the importance of setting up laws and regulations about xeno-transplantation.
2.The clinical contrast research of treatment in children of abdominal allergicpurpura
Chinese Journal of Primary Medicine and Pharmacy 2012;(24):3729-3730
Objective To explore the effective treatment in children of abdominal allergicpurpura.Methods To retrospectively analyze the clinical data of 54 children with abdominal allergicpurpura.54 cases were divided into three groups.Each 18 cases in group Ⅰ,groupⅡ,and group Ⅲ.It was used large doses of methylprednisolone in the group Ⅰ,ranitidine in the groupⅡ,and cimetidine in the groupⅢ,based on conventional treatment.To analyze the effect and adverse effect after the treatment.Results The effect of groupⅠ,and groupⅡ,was significantly higher than group Ⅲ(t=11.775,8.901,7.613,5.786,10.105,12.347,all P<0.05).There was no significant difference between groupⅠ,and group Ⅱ(P>0.05).The adverse effect of groupⅠ,was significantly higher than the other groups(x2=4.500,5.017,all P<0.05).Conclusion The treatment of hormone had obvious effect in children with abdominal allergicpurpura,but it had some risks in the gastrointestinal,so we should close observe the gastrointestinal tract in children.Ranitidine and cimetidine are the drugs of inhibiting gastric acid secretion,but the ranitidine much better than cimetidine.
3.The effects of two surgical treatment on idiopathic scoliosis
Chinese Journal of Primary Medicine and Pharmacy 2011;18(3):323-324
Objective To study and compare the effects of different surgical operation in treatment of adolescent idiopathic seoliosis. Methods 70 patients with adolescent idiopathic seoliosis and patients informed consent were selected as research object,and they were divided into group A 35 cases and group B 35 cases according to their willingness, and they were separately treated with videoassisted anterior thoracoscopic correction and traditional anterior thoracoscopic correction, then the surgical time, complications, hospital stays, rates of patients satisfaction, total effective rate and Cobb, before and after the treatment were detected and compared. Results The surgical time [(225.6 ± 30. 8) min] and hospital stays [(2. 7 ± 0. 8) d] of group A were all shorter than those of group B [( 365. 4 ±23. 8) min, (4. 8 ± 1.2 ) d] ( t = 3.26,3.78, all P < 0. 05 ), complications rate ( 8. 6% ) was lower than that of group B (20. 0% ) ( x2 = 3. 45, P < 0. 05 ), rates of patients satisfaction ( 97. 1% ) and total effective ( 97. 1% ) were higher than those of group B(80. 0% ,85.75% ) (x2 =2. 85,3.01 ,all P <0.05) ,Cobb( 14. 2 ± 5.4)°was smaller than that of group B(23. 4 ±5.6) °(t =2. 97 ,P < 0. 05). Conclusion The effect of vidcoassisted anterior thoracoscopic correction in treatment of adolescent idiopathic seoliosis was good,and complications rate was low and it was worthy of extend and application.
4.Evaluations of percutaneous dilatational tracheostomy with continuous aspiration of subglottic secretions in intensive care elder patients
Chinese Journal of General Practitioners 2012;11(6):457-458
To evaluate percutaneous dilatational tracheostomy (PDT) with continuous aspiration of subglottic secretions in intensive care unit (ICU) elder patients.A total of 32 elder patients were selected randomly for PDT and 36 controls for traditional surgical tracheostomy (TST).The PDT group required regular mechanical ventilation with continuous aspiration of subglottic secretions.The operative duration was significantly shorter in PDT group than that in TST group [ ( 10.6 ±3.4)vs.(30.9 ±7.1)min,P <0.01].Incision length was significantly less in PDT group than that in TST group [ ( 1.3 ± 0.2 ) vs.(3.2 ± 0.3 )cm,P <0.01].Blood loss volume was significantly less in PDT group than that in TST group [ ( 10.4 ±3.8 ) vs.(40.7 ± 11.7 ) ml,P < 0.01].The incidence of ventilator associated pneumonia (VAP) was significantly lower in PDT group than that in TST group ( 15.6% vs.38.9%,P < 0.05 ).With multiple advantages of mini-invasiveness,safety,simplicity,convenience and easier installation,PDT is quite suitable for elder patients in ICU.
5.Progress on study on oral lesions in patients with AIDS
Journal of Peking University(Health Sciences) 2004;0(01):-
A large number of studies showed that hairy leukoplakia,pseudomembranous candidiasis,Kaposi' sarcoma,non-Hodgkin's lymphoma,linear gingival erythema,necrotizing ulcerative periodontitis and necrotizing ulcerative gingivitis were the most common lesions in patients with HIV infection and AIDS,and their higher prevalence and incidence rates correlated with the falling CD4 counts and higher virus load of the patients.The use of highly active antiretroviral therapy(HAART) was associated with decreases in the prevalence of oral diseases.Oral manifestations may represent early signs of AIDS di-sease and call attention to disease progression.Oral fluid has been shown to possess superior sensitivity for HIV antibody detection as serum.Abstract:SUMM ARY A large number of stud ies showed that hairy leukoplakia,pseudomembranous cand id iasis,decreases in the prevalence of oral d iseases.Oral manifestations may represent early signs of AIDS d i-sease and call attention to d isease progression.Oral fluid has been shown to possess superior sensitivity forHIV antibody detection as serum.Kaposi’sarcoma,non-Hodgkin’s lymphoma,linear gingival erythema,necrotizing ulcerative periodonti-tis and necrotizing ulcerative gingivitis were the most common lesions in patients with HIV infection and AIDS,and their higher prevalence and incidence rates correlated with the falling CD4 counts and higher virus load of the patients.The use of highly active antiretroviral therapy(HAART) was associated with
6.Effect of Astragalus membranaceus and Angelica sinensis on the hemodynamics of restenosis of blood vessel in rat
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
Objective To investigate the effects of Astragalus membranaceus and Angelica sinensis on the hemodynamics and pathological features of arterial wall in restenosis of blood vessel in rats in order to find the potential mechanism of the effect of Astragalus membranaceus and Angelica sinensis in preventing restenosis after ablation of intima. Method Thirty SD rats were randomly divided into 5 groups (6 each):control group (C),model group (M),Astragalus membranaceus treatment group (H),Angelica sinensis treatment group (D),and combined Astragalus membranaceus with Angelica sinensis treatment group (HD). The restenosis model was reproduced by denuding rat's aorta endothelium with balloon catheter in all the groups except group C. After intramuscular injection of Astragalus membranaceus 0.42ml/(kg?d) in group H,Angelica sinensis 0.21ml/(kg?d) in group D,and Astragalus membranaceus 0.42ml/(kg?d) together with Angelica sinensis 0.21ml/(kg?d) in group HD for 21 days,the changes in hemodynamics and the pathological features of arterial wall were observed in all the groups. Result Compared with rats of group C,in which the intima was smooth and the smooth muscle cells (VSMCs) in media were orderly arranged,the intimal thickness of aorta,pulsatile index (PI) and resistance index (RI) increased,while the diameter of lumen,blood velocity decreased remarkably in group M. Compared with the rats in group M,the extent of hyperplasia and thickness was notably reduced,RI and PI were lower while blood velocity was lowered in group H,D and HD after being treated for 21 days. Conclusion Hyperplasia induced by remaval of endothelial cells may be reduced and blood circulation may be improved to different extents by individually or simultaneously use of Astragalus membranaceus and Angelica sinensis,thus preventing restenosis of the aorta after removal of its intima.
7.Studies on the Chemical Constituents of Korean Monkshood (Aconitum coreanum)
Chinese Traditional and Herbal Drugs 1994;0(12):-
The compounds were isolated from Aoonitum coreanum (Lev1.) Rapaics and identificd by TLC, IR, MS and NMR, as ?-sitosterol (Ⅰ), daucosterol (Ⅱ), Guan-Fu base A (Ⅲ),GuanFu bas. G (Ⅳ), condelphine (Ⅴ), Guan-Fu base Ⅰ (Ⅵ), hetisinone (Ⅶ), isoatisinum chloride (Ⅷ), atisinum chloride (Ⅸ), and Guan-Fu base z (Ⅹ) from the root. Compounds Ⅲ and Ⅸ were also found in the aerial parts of the plant. compounds Ⅱ, Ⅴ, Ⅶ and Ⅷ were obtained for the first time from this plant. Most of them exhibited antiarrhythmic activlty.
8.Clinical Meanings of Measurement of Urinaemia Patients'Parameters on Pletelet and Hemoglobin.
Journal of Medical Research 2006;0(01):-
Objective To observe changes on those parameters on pletelet and hemoglobin of urinaemia patients by treatments of dialysis.Methods candidators are divided into three groups respectively-a control group,two case groups.The two case groups are consist of patients who are treated through dialysis on not.In the three groups,the parameters on pletelet,hemoglobin,MPV and PDW are measured on hemocytometer in our laboratory. Results Dramatic difference is made in the parameters on PLT,Hb,MPV and PDW between the formers of dialysis and the control group.(P
9.Theorectical study on the relationship between hypertension and combined phlegm and blood stasis and f ive zang viscera
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(03):-
So as to explore the relationship between hypertension happen and combined phlegm and blood stasis,aswell as relations to fi ve zang-viscera,we analysis and study the related articles in literatures of past dynasties about phlegm,blood stasis with dizzy and headache,fi ve zang-viscera with dizzy and headache.We fi nd that there are relationships between phlegm and dizzy and headache,between blood stasis and dizzy and headache,between fi ve zang-viscera and dizzy and headache,as well as between phlegm,blood stasis and disorders of functions of fi ve zang-viscera.Thus,phlegm induces dizzy and headache,blood stasis induces dizzy and headache,the disorders of functions of fi ve zang-viscera cause phlegm or blood stasis,and the diseases of fi ve zang-viscera induce dizzy and headache.Therefore,the happen of dizzy and headache in hypertensive disease has direct or indirect relationships with diseases of fi ve zang-viscera,which should be noticed in clinical treatment.In clinical practices,we fi nd that in the f ive zang-viscera,the heart and kidney have the close relationship with hypertension.In literatures of past dynasties,the discuss about combined phlegm and blood stasis inducing diseases can be found,but there are no records about combined phlegm and blood stasis inducing dizzy and headache,though that is one of the most important pathological factors of hypertension happen in clinical treatment,so we should pay attention to combined phlegm and blood stasis in the treatment of hypertensive disease.