Objective To investigate the effects of mother-infant early skin-to-skin contact with different duration on neonatal behavior and breast-feeding.Methods 80 infants born from January 2017 to June were selected and randomly divided into observation group and control group,40 cases in each group.The two groups were given early maternal and infant skin contact after birth.The observation group lasted for 1 hour,while the control group lasted until the perineal wound was sutured,with an average of (30.75 ± 1.13) minutes.Comparisons were made between the two groups in terms of crying within 0-1 h,5-6 h after birth,neonatal behavioral score (BNBAS) at 11 min and 119 min after birth,breastfeeding at the first and 6 weeks and 6 months after delivery.Results At 0-1 h,5-6 h after birth,the number and duration of crying in the observation group were significantly less than those in the control group,and the BNBAS score at 119 min was significantly lower than that in the control group (P ＜ 0.05).The score of breast feeding measurement tool in the observation group was (10.45 ± 2.22) at the time of first feeding,which was significantly higher than that in the control group (8.08 ± 1.61) (P ＜0.05).The rate of exclusive breastfeeding in the observation group was 72.5％ and 52.5％ at 6 weeks and 6 months postpartum,which was significantly higher than that in the control group (37.5％ and 17.5％,P ＜ 0.05).Conclusions 1 hour of mother-infant early skin-to-skin contact can reduce awakening and cry of infant,improve the effect of breast-feeding.