Objective To investigate the modified herniorrhaphy method for adult oblique inguinal hernia. Methods From June 2001 to June 2005,the clinical data of 56 paitients with oblique inguinal her-nias were analyzed retrospectively. Results Rapid recovery,with few complication as well as low cost were achieved.Follow-up time was in 6 months to 5 years.Postoperative recurrence was not found. Conclusion With modified herniorrhaphy,the normal anatomical structure of internal ring were restored and the trans-verse fascia defect are strengthened at the same time. Normal anatomical structure of inguinal canal are main-tained. This procedure possesses a higher cure rate and postoperative recurrent rate may be reduced obviously.

目的观察脑卒中急性期接受心理康复程序治疗对患者心理障碍的疗效。方法271例脑卒中病患者随机分治疗组和对照组。两组患者均接受一般的药物治疗和功能锻炼。治疗组还接受心理康复程序治疗。结果治疗组患者各种心理障碍得到明显改善;临床疗效评定显效率和总有效率明显优于对照组。结论脑卒中急性期心理康复应和药物治疗、功能康复同步进行,并贯穿全康复过程。

Objective　The aim of this paper was to investigate endothelial dysfunction，platelet activation, and inflammation in elderly hypertensive patients and those complicated with cerebral infarction. Methods　Twenty-eight elderly hypertensive patients complicated with cerebral infarction(within 72 hours after onset of neurological symptoms),thirty-one Stage Ⅰ～Ⅱelderly hypertensive patients and twenty-eight elderly healthy individuals were selected as subjects.Their plasma concentrations of von Willebrand factor(vWF), alpha granule membrane protein-140(GMP-140), and serum concentrations of C-reaction protein(CRP) were examined. Results　Elderly hypertensive patients complicated with cerebral infarction had significantly higher plasma vWF, GMP-140, and serum CRP than elderly hypertensive patients and elderly healthy individuals. Plasma vWF and GMP-140 were higher in elderly hypertensive patients than elderly healthy individuals, whereas serum CRP was increased slightly and there was no significant difference between elderly hypertensive patients and elderly healthy individuals. Conclusion　This study suggests that elderly hypertensive patients complicated with cerebral infarction have obvious endothelial dysfunction, platelet activation, and inflammatory change. Stage Ⅰ～Ⅱ elderly hypertensive patients have obvious endothelial dysfunction and platelet activation as well.

60 mm Hg and PaCO2

The precocious puberty in female rats were induced by subcutaneous injection of N-methyl-DL-aspartate (NMA). The female rats with induced precocious puberty showed the same sexual feature as the rats that had normal puberty. NMA plays its role at the level of hypothalamus. Subcutaneous injection of NMA is an effective means to induce true precocious puberty in female rats.

OBJECTIVE To explore the incidence rate,pathogen distribution and characteristics of drug resistance of ventilator-associated pneumonia(VAP) patients due to acute lung injury and acute respiratory distress syndrome(ALI/ARDS) after severe injury,and analyze impact factors on VAP.METHODS All 183 cases with ALI/ARDS after severe injury from Jan 2004 to Mar 2008,were admiitted and given mechanic ventilation over 48 hours in our ICU and EICU.RESULTS VAP was found in 98 cases,accounted for 53.56%.Among them,42 were early-onset VAP and the other 56 were late-onset VAP.Altogether 276 pathogens were isolated,and most of them were Pseudomonas aeruginosa,Staphylococci aureus,Klebsiella pneumoniae,Acinetobacter baumannii and Escherichia coli.In 41 cases only one pathogen was isolated,the other 57 cases were with two or above pathogens.The revealed important risk factors were coma,prolonged mechanical ventilation,tracheotomy,antiacid treatment,use of antimicrobial agents and low albumin.CONCLUSIONS The incidence rate of VAP due to ALI/ARDS is high,and most of the isolated pathogens are drug resistant.Mixed infections are found commonly in these cases.

Object To study the causes for the occurrence of red skin and dark green skin of Panax quinquefolius L. during processing and its mechanism. Methods To observe the phenomena and analyze the result which simulated the processing condition of P. quinquefolius based on its components. Results The cross section of P. quinquefolius began to appear light red at 40 ℃, lasting 72 h. Whereas the time of browning was shortened with the temperature rising. The cross section of P. quinquefolius turned green while dipping in solution of Fe 3+ ion of 0 01 mol/L for 25 min. The time of turning green was shortened with the increasing concentration of Fe 2+ , Fe 3+ solution. Conclusion The results show that red skin of P. quinquefolius was caused by the Maillard reaction while drying at the excessive higher temperature. Whereas the complex reaction between phenolic substances in P. quinquefolius and metal ions during processing might result in dark green skin of P. quinquefolius. This expounds the mechanism of red skin and dark green skin turning during the P. quinquefolius processing in the theory.

Objective To establish the preparation techniques for preparing the reference substance of platycodin-D.Methods Raw material of platycodi radix was extracted with 70 %MeOH.The concentrated extract passed through D101 macroporous resin column,then the 40 %alcohol eluate was separated by silica gel column chromatography with chloroform-methanol gradient elution.The fractions contained platycodin-D were collected and purified by HPLC.Results HPLC analysis and normalization of peak areas showed the purity of the platycodin-D was 98.8 %.Conclusions The preparation techniques are simple and high yield,can be used for preparing the reference substance of platycodin-D.

Objective To study the influence of interleukin(IL)-1β,intercellular adhesion molecule(ICAM)on diahetic renal microangiopathy.Methods Sixty-two patients with type 2 diabetic mellitus were divided into three groups:normal albumin urine group(20 patients),microamount albumin urine group(22 patients),and dominancy albumin urine group(20 patients)according to their urinary albumin excretion rate(UAER).IL-1β,ICAM was measured by enzyme-linkedimmuno sorbent assay(ELISA)method in the type 2 diabetic mellitus and the healthy persons.Results The concentration of IL-1β,ICAM in the three groups with type 2 diabetic mellitus was higher than that of the twenty healthy persons(P＜0.05),higher in the dominancy albumin urine group than that in the microamount albumin urine and normal albumin urine groups(P＜0.01).The concentration of IL-1β in the microamount albumin urine group was higher than that in the normal albumin urine group(P＜0.05),the concentration of ICAM in the microamount albumin urine and normal albumin urine groups was equal(P＞0.05).Higher serum IL-1β and ICAM was associated with higher UAER(P＜0.05).The concentrations of IL-1βwas positively correlated with ICAM.Conclusion ICAM,IL-1β is probably correlated to UAER of diabetic renal microangiopathy,80 it has very important meaning and clinic value to measure the concentration of IL-1β,ICAM in serum earlier.