1.Analysis of some water soluble vitamin nutritional status of middle age and old people in Shangqiu
Weibing YIN ; Aiqin WANG ; Bin ZHAO
Chinese Journal of Primary Medicine and Pharmacy 2008;15(10):1673-1674
Objective To investigate some water soluble vitamin nutrition status of old people in Shangqiu and explore the improving ways. Methods A dietary survey was carried out and urinary VB1, VB2 and VC were test-ed. Results The intakes of VB1 ,VB2 and VC were much lower than the recommended amounts. Conclusion The intakes of VB1 ,VB2 and VC were seriously deficient in old people and preventive measures should be taken such as intaking fresh vegitable, fruits and coarse food grain.
2.Is it inflammatory linear verrucous epidermal nevus or linear psoriasis?
Bin YIN ; Yu-ping RAN ; Peng WANG ; Jebina LAMA
Chinese Medical Journal 2013;126(9):1794-1795
3.Advance in the islet transplantation for the treatment of diabetes
Wei WANG ; Bin YE ; Pengfei RONG ; Wei NIE ; Yin LIU
Chinese Journal of Digestive Surgery 2010;09(5):334-336
Islet transplantation is effective in treating diabetes, however, its clinical use is highly restricted by a series of influencing factors. This review elucidates the non-immune factors including islet purification, instant blood-mediated inflammatory response and revascularization deficit on the development of islet transplantation, and also highlights the application and perspective of islet xenotrasplantation in the treatment of diabetes.
4.Effects of Gubenkeli capsule on matrix metallopeptidase 9 and tissue inhibitor of metalloproteinase1 levels in lung tissue of a rat model of chronic obstructive pulmonary disease*
Xiaoping YANG ; Zhaoshan ZHOU ; Haibo HU ; Pingli WANG ; Bin YIN
Chinese Journal of Tissue Engineering Research 2011;15(11):2087-2090
BACKGROUND: The effectiveness and safety of traditional Chinese medicine treatment for chronic obstructive pulmonary disease (COPD) have been preliminarily approved by clinical practices.OBJECTIVE: To investigate the effects of Gubenkeli capsule on the protein expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinase1 (TIMP-1) in lung tissue of COPD model rats.METHODS: A total of 50 Wistar rats were randomly divided into five groups with 10 rats in each group: normal control, model, prednisone, Gubenkeli capsule-low dose, and Gubenkeli capsule-high dose. COPD rat models were established in all rats with the exception of the normal control rats by smoking and intratracheal instillation of LPS. At 29 days after COPD induction, rats from the prednisone, Gubenkeli capsule-low dose, Gubenkeli capsule-high dose groups were intragastrically administered prednisone (1.04 mg/kg per day), Gubenkeli capsule (0.4, 0.94 g/kg per day), once a day, to observer rat general conditions. Protein expression of MMP-9 and TIMP-1 in the lung tissue was detected by immunohistochemical methods. RESULTS AND CONCLUSION: Protein expression of MMP-9 and TIMP-1 in the lung tissue of COPD rats was significantly increased (P < 0.05). After drug intervention, the general conditions of COPD rats were greatly improved, and protein expression of MMP-9 and TIMP-1 in the lung tissue was decreased. Prednisone yields the strongest effects, followed by high-dose Gubenkeli capsule and low-dose Gubenkeli capsule. These findings demonstrate that Gubenkeli capsule alleviates the clinical manifestations of COPD model rats, improve airway remodeling, and correct the imbalance between prolease and antiprotease in a dose-response manner.
5.Clinical application of fat granule auto-graft in facial soft tissue depression
Lianbo ZHANG ; Bin WANG ; Qingguo GAO ; Guang ZHANG ; Weitian YIN
Chinese Journal of Medical Aesthetics and Cosmetology 2008;14(2):91-93
Objective To evaluate the clinical application of fat granule auto-graft in facial soft tissue depression reconstruction.Methods Autologous subcutaneous fat granules were obtained by syringe aspiration from donating site.then washed with normal saline.Small amounts of fat granules were injected into the facial sites with soft tissue depression by means of multiple passes immediately.Results We performed such fat iniection in a total of 18 cases,all of the procedures were safe and successful.In most cases,single injection were enough,only one underwent two sessions of fat iniection.All members were followed-up for 1.5 months to 24months,the average were 14 months.All facial tissue depression were reconstructed for difierent degrees.The rate of fullness and symmetry.fullness and pretty symmetry and fullness with little asymmetry were 77.8%,16.7%and 5.5%.respectively.No infection,fat necrosis or liquefaction occured.Conclusion Being satisfled in correction of deformity of facial depression.the implantation of autologous fat globules iS safe and effective with less side-effects.
6.Cloning and expression analysis of leucoanthocyanidin reductase gene in Fagopyrum dibotrys.
Jing MA ; Bin WANG ; Yin DAI ; Shunzhao SUI ; Mingyang LI
Acta Pharmaceutica Sinica 2012;47(7):953-61
The leucoanthocyantin reducase (LAR) gene, an important functional gene of catechins biosynthesis pathway, was cloned from Fagopyrum dibotrys (D.Don) Hara by degenerate PCR and rapid amplification of cDNA ends (RACE). The full-length cDNA of FdLAR is 1 581 bp (GenBank accession: JN793953), containing a 1 176 bp ORF encoding a 391 amino acids protein, and its 3'-untranslated region has an obvious polyadenylation signal. The recombinant plasmid containing FdLAR completed ORF was transformed into E. coli BL21 (DE3). The target fusion peptide with molecular weight of 66 kD was expressed under the condition of 16 degrees C and induced by IPTG at final concentration of 1.0 mmol x L(-1). Bioinformation analysis indicated that the amino acid sequence of FdLAR showed great homology to other LAR with the NADB-Rossmann conversed domain in the N-terminus. Real-time quantitative PCR was used to detect the expression levels of FdLAR gene during different development periods. The determination of flavonoids contents in appropriate rhizomes showed that the relationship between FdLAR gene expression and the accumulation of flavonoids displayed different trends during vegetative growth and reproductive growth stages, suggesting that the FdLAR gene may be involved in the pathway of flavonoid metabolisms in Fagopyrum dibotrys.
7.Study on Health Service Rescue Vest of Armed Police Forces
Bin MENG ; Hongsheng GAO ; Yundou WANG ; Ruichang WU ; Yin BAI
Chinese Medical Equipment Journal 2003;0(11):-
Objective To evaluate the performance of a kind of military health service rescue vest. Methods The author studied the structure analysis, basic performance experiments and ergonomics tests. Results The vest was scientifically designed, easy to use, in line with the ergonomics and can fulfill the requirements of military health service secure in different environment. Conclusion The secure vest can fulfill medical first aid at scene and military health service rescue. It can be used for soldiers.
8.Anterolateral minimally invasive plate osteosynthesis technique for distal humeral shaft fracture
Xian WANG ; Dong YIN ; Bin LIANG ; Dezan QIU
Journal of Central South University(Medical Sciences) 2014;(11):1157-1162
Objective: To evaluate the clinical effcacy of the modiifed anterolateral minimally invasive plate osteosynthesis technique for distal humeral shaft fracture, and to explore its feasibility, security, advantage and disadvantage. Methods: hTe clinical effcacy of 17 patients with distal humeral shatf fracture, who were treated with the anterolateral humerus minimally invasive plate osteosynthesis during 2009 to 2012, were retrospectively analyzed. hTe operative time, bleeding volume, complications, esseous union time and range of motion (ROM) of elbow were recorded, and the functional outcome of elbow joint was evaluated by Mayo elbow performance score (MEPs). The varus angle was measured in the malunion patients atfer the distal humeral shatf fracture healed. Results: All of the 17 patients obtained bony union at an average of 19.2 weeks postoperatively, an average of 4.5 screwes were inserted in distal humerus. hTe mean ROM of elbows was 133° and the MEPS were 98.2. Seven patients suffered humeral malalignment and the mean varus degrees were 8.3°. Conclusion: hTe technique of anterolateral humerus minimally invasive plate osteosynthesis is safe and feasible for distal humeral shatf, and the satisfactory clinical outcomes can be obtained by this modiifed technique. However, some of the patients may appear malunion with varus angulation of humerus.
9.Application of Electroencephalogram Non-linear Analysis (review)
Jing TENG ; Yulai WANG ; Bin YAO ; Ling YIN
Chinese Journal of Rehabilitation Theory and Practice 2007;13(8):748-750
Electroencephalogram non-linear analysis is one of the methods to study brain electric signal complexity and the mutual connection of signals based on the non-linearity principle and method. It can provide condition such as the neural networks function, contact information, the changing trajectory cerebrum function activity. It can be used for nerve spirit disease studying, the depth anaesthetize monitor ,the sleep studies in modern medicine, it breaks the ice in traditional Chinese medicine just now. The application of electroencephalogram non-linear analysis has open up an exhibition further to cerebrum's research.
10.The value of NT-probrain natriuretic peptide in predicting the severity of the coronary lesions in old patients with non-ST elevation acute coronary syndromes
Yigang YIN ; Li ZHU ; Yin REN ; Xiaobin WANG ; Zhongbao RUAN ; Jie LIN ; Jianmin LI ; Bin WANG
Chinese Journal of Geriatrics 2012;31(10):878-880
Objective To evaluate the relationship between NT-probrain natriuretic peptide (NT-proBNP) levels and the degree of coronary artery stenosis in elderly patients with non-ST elevation acute coronary syndromes (NST-ACS).Methods The levels of NT-proBNP were determined in 258 elderly patients with NST-ACS divided into 3 quartile groups based on the degree of coronary artery stenosis,and 62 normal controls.And NT-pro BNP were compared among 4 groups.Results The serum levels of NT proBNP were increased in the NST-ACS patients with single,two or three-artery lesion compared with normal controls [(197.3±80.2)ng/L,(381.7±73.5)ng/L,(496.5± 99.8) ng/L vs.(68.2 ± 36.1) ng/L].The level of NT proBNP was enhanced along with increasing severity coronary artery disease (all P<0.01).And with aging,the NT-proBNP levels were rising [aged>60-69 years:(182.34±69.13) ng/L; aged≥70-79 years:(302.68±87.51)ng/L; aged≥80 years:(482.09±82.2)ng/L] (all P<0.01).Conclusions The NT-proBNP level is enhanced along with aging and increasing severity of coronary artery stenosis in elderly NST-ACS patients.