Pulmonary valve stenosis is a common congenital heart disease,and its early diagnosis and treatment can improve growth and prognosis in children with pulmonary valve stenosis.With the development of the diagnostics and treatment,percutaneous balloon pulmonary valvuloplasty has replaced surgery as the first choice for isolated pulmonary valve stenosis.This paper reviews the recent progress in diagnosis and treatment of pulmonary valve stenosis.

Adult ; Calcium-Transporting ATPases ; metabolism ; Erythrocyte Membrane ; metabolism ; Female ; Humans ; Hydrocarbons ; adverse effects ; Lipid Peroxidation ; Male ; Middle Aged ; Occupational Exposure ; Sodium-Potassium-Exchanging ATPase ; metabolism ; Young Adult

Adult ; Female ; Humans ; Hydrocarbons ; adverse effects ; Kidney ; drug effects ; physiology ; Liver ; drug effects ; physiology ; Male ; Middle Aged ; Occupational Exposure ; adverse effects ; Smoke ; adverse effects ; Young Adult

Adult ; Female ; Humans ; Hydrocarbons ; adverse effects ; Male ; Middle Aged ; Occupational Exposure ; adverse effects ; Pulmonary Ventilation ; drug effects ; Radiography, Thoracic ; Smoke ; adverse effects ; X-Ray Film

Combined Modality Therapy ; Disease Progression ; Gastrointestinal Neoplasms ; diagnosis ; therapy ; Humans ; Physicians ; psychology

BACKGROUND:Patients with knee arthroplasty mostly had bilateral lesions. It is stil controversial to perform simultaneous bilateral surgery or unilateral arthroplasty. The focus of controversy is that bilateral arthroplasty of the same period can get a real upgrade of the repair effect if it does not increase the risk of surgery. There have always existed controversies. OBJECTIVE:To comparatively analyze simultaneous bilateral and unilateral arthroplasty from aspects of safety, economy and effects. METHODS:118 patients suffering from severe bilateral knee osteoarthritis and treated by total knee arthroplasty in the First Affiliated Hospital of Anhui Medical University from April 2011 to April 2014 were divided into simultaneous bilateral arthroplasty group (n=47) and unilateral arthroplasty group (n=71). Variables reflecting safety, economy and effects were set up and data were colected and analyzed. RESULTS AND CONCLUSION: There was no evident difference in safety between simultaneous bilateral arthroplasty and unilateral arthroplasty groups (P > 0.05). In economy and effect, simultaneous bilateral arthroplasty group was significantly better than unilateral arthroplasty group (P < 0.05). These results suggest that with the same surgical management level, if the patient could resist, simultaneous bilateral surgery should be more welcomed, while performing simultaneous bilateral surgery in patients with preoperative cardiovascular diseases should be decided carefuly. Patients with diabetes melitus preoperatively should be guarded against postoperative infection.

Being the kernel of functional gene group,the field of protein group becomes the focal point of life science research in 21th century.SELDI,which is based on the combination of chip technology and mass spectrum technology,has become the main method for filtrating tumor marker in clinical research.This paper introduces the basic principle of SELDI system and summarizes the application of SELDI to tumor marker detection in galactophore cancer.

Objective To observe the distribution and concentration of ~(125)I-nerve growth factor (NG-F) in rabbits' eyes after intravitreal injection and posterior juxtascleral injection.Methods Intravitreal injection(group A) and posterior juxtascleral injection (group B) were performed with the dosage of 30μg/100μl ~(125)I-NGF on left and right eyes in 45 white rabbits respectively.The γ-counts and the concentration of ~(125)I-NGF (%ID/g) of each ocular tissue was determined 15 and 30 minutes,and 1,3,6,12,24,and 48hours after injection.Results The ~(125)I-NGF diffusion in group A was faster in ocular content and ocular inner wall.The vitreous content of ~(125)I-NGF decreased gradually in group A,the curve changes in other eye tissues were normal.The concentration of ~(125)I-NGF reached the peak 3 hours after injection in aqueous humor,iris and ciliary body,retina,and choroids,but 6 hours after injection in sclera and 8 hours in cornea.The changes of concentration of ~(125)I-NGF in group B showed normal curve change.The peak time in group B were all 6 hours,in all the tissues except aqueous humor (3 hours).Except the high concentration in vitreous body caused by intravitreal injection,the concentration of ~(125)I-NGF in retina was the highest in group A.Conclusion Intravitreal injection of ~(125)I-NGF can gain higher concentration in each ocular tissue than posterior juxtaseleral injection,especially in retina.So intravitreal injection of NGF is a better ocular delivery method to treat the ocular fundus diseases.

Objective To analyze the IgG variances between workmen and workwomen in x-ray room,and to provide reference for the assessment of staff in the department of radiology.Methods The staff in the department of radiology who recieved health examination from Janurary 2012 to Janurary 2016 were divided into the male group and the female group.The health examination data of 75 staff in each group were slected and the basic immunization level of the two groups were tested.And then compared the the IgG variances between the two groups.The analysis were conducted by two means of grouping,namely the working age of staff (less than 10 years,between 10 and 20 years, and over 20 years)and the age of staff (aged 21 to 30,aged 31 to 50,aged 51 to 78).Results The level of IgG in the female group were higher than that in the male group when their working age were less than 10 years,and the difference was significant (P <0.05).Both in the male group and the female group,the level of IgG in staff aged 31 to 50 were lower than the others,and the difference was significant (P <0.05).Conclusion The level of IgG in female staff were higher than that in the male staff in different age stages,and it increased with the increase of working age.To analyze the IgG variances of staff the in x-ray room could provide reference for assessment of physiclal status.

To improve standardization and consensus regarding interpreting,and reporting CT and MRI scans of the liver in patients with high-risk HCC,Liver Imaging Reporting and Data System (LI-RADS) was launched in 2011 and subsequently modified in 2013 and 2014,respectively.Major diagnostic imaging features for HCC are hyper-enhancement in the arterial phase,rapid dissection in the portal vein phase and balance phase,capsule presence and appearance,interval threshold tumor growth and tumor diameter.LI-RADS categorizes nodules recognized at CT or MRI as LR-1 (definitively benign),LI-RADS is a system of standardized criteria for interpreting liver CT and MR images of patients at risk of hepatocellular carcinoma in higher interobserver reliability and faster categorization while maintaining diagnostic accuracy.LR-2 (probably benign),LR-3 (intermediate probability of being HCC),LR-4 (probably HCC) and LR-5 (definitively HCC).According to diagnostic classification,different options for treatment recommendations are adopted by surgeons including continue standard surveillance,regular follow-up,alternative imaging method,multidisciplinary discussion,liver resection or transplantation.LI-RADS is a system of standardized criteria for interpreting liver CT and MR images of patients at risk of hepatocellular carcinoma in higher interobserver reliability and faster categorization while maintaining diagnostic accuracy.