Objective To study effect of self-care ability and subjective well-being of Based on peer support surgery nursing intervention for ICU surgery patients. Methods A total of172 cases patients with ICU surgery from July 2014 to June 2015 were divided into observation group and control group, the observation group given based on peer support nursing intervention, the control group routine nursing intervention, and followed up for 6 months, self-care ability, anxiety, depression, and subjective well- being were compared between two groups. Results Followed up for 6 months, the observation group life attitude, life style, diet adjustment, treatment compliance were (79.92 ± 7.23), (82.36 ± 7.15), (83.57±7.25), (85.73±7.45) points, significantly higher than the control group (72.25±7.12), (74.79±6.89), (73.66±7.08), (76.68±7.13) points, (t=7.010-9.069, P<0.01). Anxiety and depression scores were 47.16± 4.27, 48.58±5.32,which were significantly lower than the control group 50.48±4.56, 53.37±5.75 (t=4.928, 5.671, P<0.05). Health worry, life satisfaction and interests, energy, sad or happy mood, emotion and behavior control, relaxation and tension, subjective well-being scored 8.12±0.95, 7.68±0.85, 16.45±2.31, 13.02±1.24,13.25±1.33, 17.56±2.45, 78.69±8.02, were significantly higher than the control group 7.52± 0.82, 6.31±0.72,13.25±1.22, 12.35±1.22, 12.02±1.21, 14.36±1.42, 67.12±7.02 (t=3.572-11.405, P<0.05 or 0.01). Conclusions Based on peer support surgery nursing intervention help to improve self-care ability of surgery patients, alleviate the negative mood, and improve subjective well-being.

Objective To investigate the influencing factors of children pneumonia hospitalization expense and provide refer‐ence for its expense control .Methods Path analysis was performed on the hospitalization expense and its influencing factors based on 927 pneumonia children in a hospital in Chongqing in 2011 .Results Multivariate regression analyasis showed that the influen‐cing factors of children pneumonia hospitalization expense were proportion of drug expense ,length of hospital stay ,type of pay‐ment ,admission condition ,therapeutic outcome and age .The coefficient of determination (R2 =0 .867 ,F=597 .552 ,P<0 .01) .Be‐sides ,proportion of drugs ,admission condition and therapeutic outcome had indirect effects by influencing hospital stay .The coeffi‐cient of determination (R2 =0 .506 F=330 .336 ,P<0 .01) .According to the total coefficient of path analysis ,the factors of influen‐cing hospitalization expense were listed in descending order as follows :proportion of drug expense ,length of hospital stay ,therapeu‐tic outcome ,type of payment ,admission condition and age .Conclusion Reducing drug proportion ,length of hospital stay ,and strengthening supervision on medicare patients′ expense are effective measurements to control children pneumonia hospitalization ex penses .

Using Low Shear-30 rheometer, we studied apparent viscosities at high (51.2-128.5s~(-1)), moderate (11.02-37.6s~(-1)), and Low (0.376-8.11s~(-1)) shear rate, viscoelastic properties of whole blood and hemodynamic parameters in 10 patients with acute myocardiac infarction(AMI), comparing with 10 patients with angina pectoris (AP) and 11 normal subjects(NS). It was demostrated that the apparent viscosities of whole blood at different shear rates mentionned above and viscoelastic properties of whole blood (the dynamic modulus G′, the loss modulus G″, "the viscous ?′ and the elastic component ?″ of complex viscosity) increased distinctly and parameters of cardiac function (EF, CO, LVET, PEP/LVET, HI, SV and CI) were abnormal obviously in AMI, in comparing with AP and NS (P

Relationship between hemorheology and blood gas analysis was studied in 37aged patients with chronic cor pulmonale, including 17 instable and 20 stable. Apparentviscosity (?a) of shear rate of 230.4 (?a(H)) and 5.76/s (?a(L)), TK values, redcell aggregation index(RAI) and PaCO_2 in instable chronic cor pulmonale (AG) were muchhigher than that of stable. patients (BG). Oxygen delivery index (OD) and PaO_2 in AGwere lower than in BG. ?a (H) was negatively correlated with OD and pH (r=-0.58,-0.40, P

External fixators have been widely u sed in treatment of war trauma due to t heir small size,light weight,easy application,and convenience in transport.There are several types of military external fixato r,such as FESSA(Fixateur Externe du Service de Sant?des Arm?es),CMC(Croatian Medical Corps),Synthes and Hoffman-Ⅱ.All of these have been used on the battlefields of Rwandese War,Croatia Wa r and the first Persian Gulf War.Most of military external fixators are unilateral connectable-joint.For temp orary fixation,one bar is enough;by adding another parallel bar,the fixation can be use d for long-time fixing.Facing with a great demand of war trauma treatment ,we should develop new types of military external fixator with more simplicity and less size or weight. [

Objective Vascular endothelial growth factor( VEGF) is the key to regulat vascularization, and plays an important role in the development of acute myeloid leukemia. With the understanding of anti?tumor angiopoiesis, researchers take VEGF and its receptors as targets, continuously exploring the new drug. We summarized the biological characteristics of VEGF, vascular?targeted therapy and the clinical application of drugs.

BACKGROUND:The existing bone grafting apparatus are al long tubular-shape, antegrade bone grafting; however, the bone grains within the tube were difficult to put through, along with large bone loss. OBJECTIVE:To design a new concept of minimaly invasive bone grafting apparatus, so as to achieve the minimaly invasive bone grafting in vertebral body and intervertebral space. METHODS: On Solidworks 2012 software platform, the 3D three-dimensional solid modeling technology was employed to design a new concept of gun-shape bone grafting device with the characteristics of headend reversely placing at the grafting position and antegrade pushout, against the problems such as antegrade bone grafting, long bone grafting path and difficulty in bone grafting existing in precious percutaneous or/and transpedicular bone graft apparatus. The virtual assembly and simulative bone grafting surgery were performed with the bone grafting apparatus for observation of the instrument matching degree and grafting surgical procedures. RESULTS AND CONCLUSION: A set of minimaly invasive gun-shape bone grafting apparatus was successfuly designed; its length was 20 cm in total; the length of the front semi-closed bone tube was 2.5 cm. There are two kinds of diameter specifications: inner diameter of 3.5 mm/outer diameter of 4 mm, and inner diameter of 5 mm/outer diameter of 6 mm. Virtual assembly revealed that the grafting apparatus were wel matched. Stimulative surgery displayed that the bone grain loading and launch were simple. The gun-shape bone grafting device is reasonable in design, avoiding pushing too long distance, bone pushing difficulties, bone loss and other problems in previous tubular bone grafting apparatus. Percutaneous, endoscopic vertebrae or intervertebral space minimaly invasive bone grafting can be performed with this apparatus.

Acupuncture Therapy ; Adolescent ; Craniocerebral Trauma ; complications ; Humans ; Male ; Optic Nerve Injuries ; etiology ; physiopathology ; therapy ; Vision, Ocular

To analyze the compatibility regularity of compound traditional Chinese medicine (TCM) patents for treating dyslipidemia, and provide basis for the clinical development and research of new TCM for treating dyslipidemia. Totally 243 compound traditional Chinese medicine patents for treating dyslipidemia were collected from the national patent database from September 1985 to March 2014 and analyzed by using drug frequency, association rules, complex network and entropy method of Traditional Chinese Medicine Inheritance System (V1.1). The commonest single medicine in the treatment of dyslipidemia is Crataegi Fructus 109 (44.86%). The commonest pair medicine is Crataegi Fructus-Salviae Miltiorrhizae Radix et Rhizoma 53 (21.81%). The commonest corner drug is Crataegi Fructus-Cassiae Semen-Polygoni Multiflori Radix 25 (10.29%). The common prescriptions on basis of association rules are Prunellae Spica-->Salviae Miltiorrhizae Radix et Rhizoma (0.833), Rhei Radix et Rhizoma, Alismatis Rhizoma-->Polygoni Multiflori Radix (1.00), Salviae Miltiorrhizae Radix et Rhizoma, Cassiae Semen, Alismatis Rhizoma-->Polygoni Multiflori Radix (0.929). The core drugs based on complex networks are Salviae Miltiorrhizae Radix et Rhizoma and Crataegi Fructus. The new prescriptions extracted by entropy method are Atractylodis Macrocephalae Rhizoma-Glycyrrhizae Radix et Rhizoma-Platycladi Semen-Stephaniae Tetrandrae Radix; Citri Reticulatae Pericarpium-Poria-Coicis Semen-Pinelliae Rhizoma. This study shows the regularity in the compatibility of compound TCM patents treating dyslipidemia, suggesting that future studies on new traditional Chinese medicines treating dyslipidemia should focus on the following six aspects: (1) Single medicine should be preferred: e. g. Crataegi Fructus; (2) Pair medicines should be preferred: e. g. Crataegi Fructus-Salviae Miltiorrhizae Radix et Rhizoma; (3) Corner drugs should be preferred: e. g. Crataegi Fructus, Cassiae Semen, Polygoni Multiflori Radix; (4) The compatibility among drugs shall be given attention, and highly correlated drugs should be preferred: e. g. Prunellae Spica, Salviae Miltiorrhizae Radix et Rhizoma; Rhei Radix et Rhizoma, Alismatis Rhizoma, Polygoni Multiflori Radix; Salviae Miltiorrhizae Radix et Rhizoma, Cassiae Semen, Alismatis Rhizoma, Polygoni Multiflori Radix; (5) Core drugs should be dominant and compatible, e. g. in the digestion catharsis method, the core drugs is Crataegi Fructus and compatible with Salviae Miltiorrhizae Radix et Rhizoma; (6) Application of new prescriptions: Atractylodis Macrocephalae Rhizoma, Glycyrrhizae Radix et Rhizoma, Platycladi Semen, Stephaniae Tetrandrae Radix; Citri Reticulatae Pericarpium, Poria, Coicis Semen, Pinelliae Rhizoma.
Dyslipidemias ; drug therapy ; Entropy ; Humans ; Medicine, Chinese Traditional ; Patents as Topic

Objective To evaluate the effect of stellate ganglion block (SGB) on cerebral vasospasm in patients undergoing intracranial aneurysm surgery. Methods Forty ASA Ⅱ or Ⅲ patients aged 14-64 yr weighing 40-81 kg undergoing intracranial aneurysm clipping were randomly divided into 2 groups ( n = 20 each): group control (group C) and group SGB. Left SGB was performed with 0.25% ropivacaine 10 ml immediately after intubation. Successful block was verified by development of Homer syndrome within 15 min after block. Anesthesia was induced with midazolam, propofol, fentanyl and vecuronium and maintained with isoflurane inhalation and intermittent iv boluses of fcntanyl and vecuronium. The patients were intubated and mechanically ventilated. PETCO2 was maintained at 30-35 mm Hg. BIS was maintained at 50-60. Right internal jugular vein was cannulated and the catheter was threaded cranially until resistance was met for blood sampling. Blood samples were collected before skin incision (T1), before clipping of aneurysm (T2), at 30 min after clipping (T3 ), and at the end of surgery (T4) for determination of plasma concentrations of endothelin (ET), calcium gene-related peptide (CGRP) and S100B protein. Transcranial Doppler was used to measure the flow rate of blood in bilateral middle cerebral artery and extracranial carotid artery at 1 and 3 days after surgery. All patients were observed for incidence of brain ischemia during 1-7 days after surgery. Results Plasma ET and S100B protein concentrations were significantly decreased, while plasma CGRP concentration was significantly increased after clipping of aneurysm at T3 and T4 in group SGB as compared with group C. The incidence of cerebral vasospasm and brain ischemia was significantly lower in group SGB than in group C. Conclusion SGB performed before operation can significantly reduce the incidence of cerebral vasospasm after clipping of intracranial aneurysm by inhibiting the release of ET and promoting the release of CGRP.