Objective To study the relationship between cognitive dysfunction and depression and event-related potential(ERP) in patients with silent brain infarction(SBI).Methods 68 SBI patients were tested by the Hamilton Depression Rating Scale for Depression(HAMD),scale of mini mental state examination(MMSE)and ERP;and the results were compared with those in 55 patients without cerebral infarction(control group).Results In the SBI group,the HAMD score was ≥17 in 31(45.6%)cases(depression subgroup)and

Objective To analyze the reasons of the occlusal disorder after mistaken concrescence of maxillofacial fracture, to observe the effect of the physiotherapy for the masticatory movement and the masticatory efficiency after occlusal reconstruction with fixed prosthesis. Methods The reasons of occlusal disorder of 45 patients were analyzed by reviewing the case history and clinical examination. Ultrasound diathermy and laser irradiation were used to help improve masticatory movement. The fixed prosthesis was used to reconstruct the occlusal relationship. Masticatory efficiency was measured with the method of sift out before treatment, one month and one year after treatment. Results The main reason of occlusal disorder was the delay of treatment because of the other treatment of body after trauma. The physiotherapy was effective in improving the masticatory movement. Statistically analysis showed the significantly difference before and after occlusal reconstruction with fixed prosthesis ( P

AIM: To study the effects of L-arginine on sebaceous gland hyperplasia in rats. METHODS: 10 mg?kg -1?d -11 of L-arginine was poured into the stomach in Sprague-Dawley rats for 7-14 d. The pathology phenomenon was observed in the rat skin. RESULTS: The backside skin of the male SD rats showed dewiness, greasiness and engrained yellow. The incidence was 100% for 7 d in the male SD rats, 80% in the female SD rats for 14 d, but 100% in the immature female SD rats for 14 d. CONCLUSION: L-arg nine can facilitate the hyperplasia of sebaceous gland in SD rats.

Objective To observe the relationship between serum bilirubin levels of elderly heart failure patients and type, clinical symptom and prognosis of the heart failure. To explore the pathophysiological role of heme oxygenase 1/CO bilirubin system in the pathogenesis of the heart failure. Methods Serum total bilirubin and direct bilirubin and indrect bilirubin levels of 57 inpatients admitted to our depatment because of heart failure from April 1998 to June 2000 were examined in the second day, first and second week after admission, respectively. Results (1) Compared with the recovery stage of the heart failure, the serum total bilirubin levels during the heart failure attack increased by 52 9% and 78 9%, respectively than the first and second week after the attack(26 1 ?mol/L vs 17 4 ?mol/L and 14 6 ?mol/L, P

Objective:To observe the effect of soluble CD14 (sCD14) on the inducing activity of lipopolysaccharide(LPS) on human gingival fibroblasts(HGFs). Methods:In vitro cultured HGFs were stimulated by FITC labeled LPS at the concentration of 0 (control), 100 ng/ml, 100 ng/ml LPS+100 ?g/ml sCD14 and 100 ng/ml LPS+100 ?g/ml ENP respectively for 24 h. The binding activity of LPS to HGFs was measured in the level of mean fluorescence intensity of FITC-LPS.TNF-? and IL-6 in the culture supernatant were measured by ELISA. Results:The binding activity of FITC-LPS to HGFs and the level of TNF-? and IL-6 in culture supernatant were significantly decreased in sCD14 and ENP group(P

With the further expansion of the connotations of the quality of medical services and the establishment of the bio psycho social medical model, it has become necessary to redefine quality evaluation of medical services. The authors give their interpretation of the quality of medical services and its evaluation from several perspectives, discuss the goals of quality evaluation of medical services, and expound in a rational manner the entire process and content of quality evaluation. On the basis of this, they make a comment on previous quality evaluation units and methods and put forward the tentative idea of conducting overall quality evaluation of whole process medical services.

Objective:To investigate the expression of anti-endothelial cell antibodies(AECA) in patients serum with anti-neutrophil cytoplasmic antibody( ANCA) negative pauci-immune deposition type crescentic glomerulonephritis and its relationship with clinical signatures. Methods:We selected 94 pauci-immune deposition type crescentic glomerulonephritis patients from 2010 to 2015 treated in our hospital,45 of which with ANCA-negative( observation group) and 49 cases of ANCA-positive patients ( control group) , AECA levels of each groups serum were detected by Western blot test. Results: The average age of the observation group and Bermingham vasculitis activity score(BVAS) respectively (41. 08 +9. 43) years old and (15. 03 +3. 82),significantly lower than the control group (P<0. 05);the observation group had fever,joint pain accounted for 26. 67% and 13. 33%,significantly lower than the control group ( P<0. 05 );the observation group of nephrotic syndrome accounted for 48. 89%, higher than the control group ( P<0. 05);observation group positive rate of serum AECA was 46. 67%,significantly lower than the control group 81. 63% (P<0. 05);the observation group IgG-AECA identified 7 proteins,while the control group had identified 11 proteins,of which the observation group the positive rate of anti 90 kD antibody was 13. 33%( 6/45 ) , significantly lower than the control group 51. 02%( 25/49 ) ( P<0. 05 );observation group of anti 76 kD antibody positive patients had rash ratio of 100%, significantly higher than negative patients ( P<0. 05),anti 200 kD antibody positive the BVAS score of the patients was (18. 02 + 2. 51),which was significantly higher than that of the negative patients ( P < 0. 05 ) . Conclusion: The different level of AECA in ANCA negative pauci-immune crescentic glomerulonephritis patients may be associated with certain clinical manifestations;clinical manifestations differences between the ANCA negative and positive patients may be associated with different expression of the AECA related,the detail need a further study.

ObjectiveTo search for the optimum external masking time and tonal models for patients with tinnitus.MethodsTwenty-seven patients with cochlear tinnitus were selected respectively from three different out-patients departments and divided into three groups. Nine patients in every group were treated with different masking parameters according to factorial design which had three masking noises, i.e. narrow band noise (NBN), wide band noise (WBN), speech noise (SN),and three masking time ranges, i.e. 15,30,45 minutes. The results before and after treatment were compared and analysed with analysis of variance (ANOVA). ResultsThe treatment effect when masking for 15 minutes was worse than that for 30,45 minutes, but there was no difference between 30 and 45 minutes. The NBN had the best effect when tinnitus signal was single, the WBN was effective for tinnitus with multiple sounds. ConclusionNBN or WBN masking for 30 minutes showed better therapeutic effect.

Objective To evaluate the therapeutic effect of long-pulsed Nd:YAG 1064 laser on hyperplastic scars by using a rabbit ear model.Methods Five female and five male New Zealand long-ear white rabbits weighting 2.0-2.5 kg were used in this experiment.Four square full-thickness skin wounds sized 1.5 cm x1.5 cm were created on the ventral surface of each ear to develop a model of hyperplastic scar.Finally,a total of 74 hyperplastic scars developed on the 80 wounds,and the scars on the left and right ears served as the control (unirradiated) and treatment (irradiated with long-pulsed 1064 nm Nd:YAG laser) group,respectively.After 30 days of irradiation,the color and texture of scars were observed and the scar thickness was measured by color Doppler ultrasonogTaphy.Then,the scars were harvested followed by the analysis of density of fibroblasts and microvessels as well as the changes in collagen fibers in scars by HE staining,CD31 staining and Masson staining,respectively.Results A decrease was observed in the color,hardness and thickness of scars in the irradiated ears compared with the unirradiated ears.The average thickness of scars,microvessel density and fibroblast density in scars were significantly lower in the treatment group than in the control group(2.137vs.3.089 am,t=5.72,P<0.01;38.333/mm2vs.68.056/mm2,t=4.93,P<0.01;166.940/mm2vs.355.000/mm2,t=13.36.P<0.01).Masson staining revealed a disorganized arrangement of collagen fibers in the control group but a sparse and regular alignment in the treatment group.Conclusion Long-pulsed 1064 nm Nd:YAG laser may promote the shrinkage and suppress the hyperplasia of scars.

Objective: To strengthen the education of ethics,honor and humiliation,and humanities for the working staff in community healthcare service,so as to better serve the community residents.Method: To strengthen the education of ethics,honor and humiliation,and humanities for the working staff in community healthcare service,and check the outcome.Conclusion: It is necessary to recognize the humanistic function of community healthcare service,strengthen practice and the ability of healthcare service to improve residents' trust and satisfaction of community healthcare service.