Objective:To understand the epidemic situation of Redondoviridae in Beijing and analyze its epidemiologic characteristics.Methods:Pharyngeal swab samples of healthy people and patients with acute respiratory infection in Beijing, including influenza like cases and severe acute respiratory infection (SARI) cases in hospitals were collected. Real time PCR was used to detect the nucleic acid of Redondoviridae. The positive samples were amplified and sequenced to analyze their species. The age and sex distribution of patients and species distribution of Redondoviridae were obtained through statistical analysis. Multiplex PCR was used to detect other common respiratory pathogens in the positive samples of Redondoviridae in influenza like cases and SARI cases, and the pathogenicity of Redondoviridae was analyzed.Results:The positive rates of Redondoviridae in healthy people and acute respiratory infection cases were 20.48% (189/923) and 11.23% (43/390), respectively, with a statistically significant difference ( P<0.05). The positive rate of male was higher than that of female in the healthy population, and the positive rate of the elderly group was higher than that of the adult group and the underage group, with a statistically significant difference ( P<0.05). The positive rate of male patients with acute respiratory tract infection was higher than that of female patients, but there was no significant difference. The proportion of Vientovirus in the positive samples of Redondoviridae was higher than that of Brisavirus, and the difference was statistically significant ( P<0.05). Among the throat swabs of respiratory tract infection cases, 43 were positive for Redondoviridae, of whom 24 were not detected for other pathogens. Conclusions:Redondoviridae widely exists in healthy people of all age groups in Beijing, and is also found in acute respiratory infection cases. The positive rate of Redondoviridae is different in different ages and genders. Both Vientovirus and Brisavirus were detected, and the proportion of Vientovirus was significantly higher than Brisavirus.

The theory of"lung governing skin and hair"has always occupied an important position in the clinical practice of traditional Chinese medicine.However,in western medicine,the close correlation between the lungs and the skin in health and disease has not been established.The difference between these two medical views has triggered an urgent need for the scientific interpretation and clinical application of the theory of"lung governing skin and hair"in western medicine.Therefore,the purpose of this paper is to discuss the application of"lung governing skin and hair"in chinese medicine and the correlation between the lung and the skin in western medicine from the connotation and history of"lung governing skin and hair"in Chinese medicine.In addition,we will discuss the common pathologic biomarkers of lung and skin diseases in western medicine and the co-morbidities between lung and skin,with the aim to provide new ideas for the clinical diagnosis and treatment of lung and skin diseases and modern research,as well as providing a direction for the integration of the theory of"lung governing skin and hair"into the clinical practice of western medicine.