[Objective]To summarize febrile disease syndrome and treatment characteristics in“Common Treatise of Febrile Diseases”of Yu Genchu, add new meanings to the research of the doctrine of febrile disease. [Methods] Through col ating febrile disease contents in“Common Treatise of Febrile Diseases”to analyse and discuss. [Results] The name of febrile disease appears rarely in“Common Treatise of Febrile Diseases”,but the contents of the book contain febrile disease,such as febrile disease diagnosis,treatment and aftercare. [Conclusion]The name of “typhoid fever”is throughout the whole book,but as a scholar of younger age,we should know it is generalized “typhoid fever”, which is the name of seasonal exogenous disease.The book explains the original idea of Zhongjing and integrates with the theories of the doctors of febrile diseases, reflecting Yu Genchu ’s academic idea of cold-warm combination and initiating the research of Shao Pai Shang Han.

[Objective]To explore the six medicinal ingredients,namely"(臧)Zangdu,Luru,Shashen,Baishashen,Shuchong and Fangji(ji)",in the Wucheng Hanjian prescription,in order to restore their original appearance.[Methods]Through literature search and double evidence method,a large number of relevant papers and books were consulted,and the research results were compared and summarized.[Results]This prescription consists of twenty-six medicinal ingredients,and the methods of preparation are diverse."(臧)Zangdu"should be"Daizhe"used by modern people;"Shashen"should be"Nanshashen",and"Baishashen"should be"Beishashen";"Shuchong"should be"Zhechong";there are two possible specific medicinal ingredients for"Luru",one is"Qucao",and the other is"lvru";"Fangji(ji)"should be"Fangkui".This prescription is used to treat"cold and dampness epidemic"with the etiology of cold and dampness,the main symptoms of constipation,coughing,and body pain,and the pathogenesis of external cold,internal drinking,and heat stagnation.[Conclusion]The research and restoration of the true appearance of the Wucheng Hanjian prescription is not only beneficial for further exploring the development process of traditional medicine,but also has practical reference significance for modern research on Chinese medicine,and also has certain value for the tracing research of Zhe school of traditional Chinese medicine.