Objective To summarize the key points of nursing care in reservation of catheters in 11 cases of nasopharyngeal carcinoma patients who received concurrent chemo-radiotherapy with symptomatic thrombosis after ultrasound-guided implantation of double-lumen PICCs(PowerPICC).Methods From January,2014 to December,2015,totally 11 cases with symptomatic venous thromboembolism were identified among 109 cases of nasopharyngeal carcinoma patients receiving concurrent radiotherapy and chemotherapy,and observation and nursing care were provided at the early stage of thrombosis and during thrombosis.Results All double-lumen PICCs were reserved,and no recurrence or aggravation of thrombosis was recorded to the end of the treatment.The duration of carrying PICCs was 67～89(77.45±6.65) days.Conclusion With careful treatment and nursing,PICC catheter-related complications can be reduced and the duration of carrying catheters can be prolonged,which leads to accomplishment of the treatment plan for patients.

Objective:To analyze the prevalence and burden of herpangina(HA)in Chinese children from 2016 to 2020, which provides basic data reference for the diagnosis, treatment and prevention and control of HA in China.Methods:The homepage information of hospitalized children with HA were collected from 27 children′s hospitals and maternal and child health hospitals in 23 provinces of China from 2016 to 2020 and the epidemiology, severity and disease burden of HA were descriptively and statistically analyzed.Results:A total of 24, 099 hospitalized children with HA were reported from 27 children′s hospitals and maternal and child health hospitals in 2016-2020. In all that the hospitalized children, the male-to-female ratio was 1.46∶1 and 23, 432 children (97.23%) were ≤ 6 years old. HA onset lasted from April to September and its peak was in June or July every year except 2020. The largest number of hospitalized children with HA were found in East China (8, 520/23, 849; 35.72%). During study years, the proportion of hospitalized children with HA among all admissions in 27 investigated hospitals was 0.42% (24, 099/5, 790, 910). In terms of regions, the highest proportion was in Northeast China 0.69% (1, 720/249, 244). A total of 1, 510 (6.27%) children were severe cases and the male-to-female ratio was about 1.35∶1; 1, 326 (87.81%) children were ≤ 3 years old and the highest proportion of severe cases was in 28 days to ≤ 1 years old children (7.47%, 784/10, 494). The median of expenses for hospitalized children with HA was 3, 570.41 RMB (IQR 2, 698.03-4, 747.30), and the median hospital stay was 5 days (IQR 4-6).Conclusions:HA onset in China was predominantly in summer and at the age of ≤ 6 years. Meanwhile, owing to a large number of hospitalized children with HA and the high expenditures they generated, HA caused a considerable disease burden.

Objective:This study aimed to provide basic data for the prevention, diagnosis and treatment of pediatric viral myocarditis (VMC) in China through analyzing the epidemic characteristics and disease burden of pediatric inpatients with VMC from 2016 to 2021.Methods:We performed a descriptive statistical analysis to the age, genders, seasons, regions and hospitalization cost and days of pediatric VMC inpatients and the death. All of the information was obtained from 27 Children′s hospitals or Maternal and Child Health hospitals of 23 provinces of China from 2016 to 2021.Results:A total of 7 647 599 cases including 1 646 VMC inpatients were admitted into our study. The annual numbers of hospitalizations were 173, 227, 313, 301, 295 and 337, with the hospitalized constituent ratios being 14.9/100 000, 17.9/100 000, 23.0/100 000, 20.5/100 000, 26.5/100 000 and 26.4/100 000 from 2016 to 2021. In recent 6 years, the proportion of VMC hospitalizations had increased yearly ( P<0.001), and had associated with the onset age ( P<0.001). Aged 12-≤18 years owned the highest hospitalized constituent ratio. The Northeast of China owned the largest number of VMC inpatients, and the East second to it. Among the 1 646 VMC children, there were 68 deaths, with the hospitalized case fatality rate of 4.13%. There were no significant differences between genders, age, seasons, years and fatality rate of VMC inpatients. For the diseases burden, the median of hospitalization days of all VMC inpatients was 10 days (IQR 6, 21), and the median of hospitalization cost was 1 1 842.3 RMB (IQR 6 969.22, 19 714.78). The median of hospitalization days of deceased VMC children was only 1 day (IQR 1, 3), the median cost could be 8 874.03 RMB (IQR 5 277.94, 5 6 151.59). Conclusions:In this study, we found that proportion of hospitalization of VMC children increased year by year, adolescence might be a risk factor of VMC. The fatality of VMC inpatients could be up to 4.13%, and the death led to a huge economic burden of society, family and individuals.