1.Assessment of emotional valence of the neutral pictures: it depends on the category
Chinese Journal of Behavioral Medicine and Brain Science 2013;22(7):624-626
Objective To explore which category of pictures could induce neutral emotion better for male and female respectively,and investigate the effects of inducing neutral emotion with eight categories of neutral pictures,including the nature,plants,animals,humans,culture,death-waste,food and computer graphics.Methods Using selected stimuli from the simple version (revised by Huang and Luo(2004)) of the International Affective Picture System (IAPS),the rating of calm-mood degree were collected for 135 neutral pictures based on 186 undergraduate students (78 male and 108 female).Results The pictures in the categories of plants(6.87 ±1.53),nature(7.00 ± 1.73) and culture(6.93 ± 1.37) induced neutral emotion significantly better than human (5.89 ± 1.49),computer graphics (5.94 ± 1.93) and food (5.87 ± 2.03) (P < 0.05) which were better than animals (5.03 ± 1.70) and death-waste (4.71 ± 1.94) (P < 0.05).In addition,gender difference was found in rating calm-mood degree for death-waste,people and animals categories.For these categories males showed higher rating for the calm-mood degree than females (P< 0.05),while for the other categories,there was no gender difference.Conclusion The ideal categories of neutral pictures that inducing neutral emotion are plants,nature and culture.This study provide empirical evidences for selecting and using pictures to induce relative calm mood in the emotional study,and the contribution of this study to the clinical research is discussed.
2.Clinical observation on treatment of chronic hepatitis B and hepatic fibrosis with Fugan Tablet
Chinese Traditional Patent Medicine 1992;0(12):-
AIM: In order to observe the curative effect of Fugan Tablet on chronic hepatitis B and hepatic fibrosis,we held clinical observation of 120 cases of chronic hepatitis B and hepatic fibrosis. METHODS: 120 cases of chronic hepatitis B and hepatic fibrosis were divided into curative group with Fugan Tablet and control group with Hepatic Ling Injection,and the change of symptom,hepatic function,iconography index,hepatic fibrosis in serum and the hepatic histology were observed before and after the treatment,then the curative result of the two groups was compared. RESULTS: The total effective percentage of curative group was 88.33%,and the total effective percentage of control group was 68.33%.Comparing the two groups,the difference was obvious(P
3.Several interpretation of improtant clinical trials on antihypertensive therapy
Chinese Journal of Practical Internal Medicine 2003;0(01):-
In the PROFESS and TRANSCEND trials,telmisartan(80 mg daily),compared with placebo,reduced systolic blood pressure by about 4 mmHg,but did not influence the primary composite cardiovascular endpoint.The difference between the ACCOMPLISH and ALLHAT trials in the amlodipine-diuretic comparison might be attributed to the combination of amlodipine with an angiotensin converting enzyme inhibitor in the ACCOMPLISH trial,which provided further evidence that by smoothly controlling blood pressure over 24 hours amlodipine prevent vascular events better than other antihypertensive drugs.
4.Determination of residual organic solvents in Ginkgo biloba Leaves for injection by headspace GC
Teng WANG ; Yifang YANG ;
Chinese Traditional Patent Medicine 1992;0(05):-
Objective:To establish a method for analysis of residual organic solvents (methanol, ethanol, acetone, ethyl acetate) in Ginkgo biloba Leaves for injection.Methods: The contents of residual solvents in Ginkgo biloba Leaves for injection were determined by headspace GC on HP 5 column, with FID detector, high purity nitrogen as the carries gas.Results: There was a good linearity ( r :0.9909~0.9999). The RSD of precision and accuracy was less than 5%, the average recovery rate was in the range of 93.06%~113.78%.Conclusions: The method was simple, quick and accurate and can be used for quality control of Chinese patent medicine.
5.Clinical Observation on Naomaitong Capsules for Treatment of 86 Cases of Cerebral Thrombosis
Yifang WANG ; Jiaxiang WANG ; Xiaohua GUO
Journal of Traditional Chinese Medicine 1993;0(10):-
Objective: To observe therapeutic effect of Naomaitong Capsules on cerebral thrombosis and to study the mechanism. Methods: 160 cases of thrombosis were randomly divided into a treatment group(n=86) and a control group(n=74), and they were treated by Naomaitong Capsules and LuoXinTong, respectively. After treatment for 3 months therapeutic effects were investigated. Results: The cured and markedly effective rate was 81.39% and the total effective rate was 95.35% in the treatment group with significant differences as compared with those in the control group (P
6.Study of cognitive tendencies in recognizing negative emotional faces
Pingping MA ; Yifang WANG ; Ping WEI
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(2):157-159
Objective To study the cognitive tendencies in recognizing negative emotional faces.Methods The experiment used the traditional flanker paradigm for reference.Forty-eight university students (19 males,29 females) finished the flanker tasks deigned by E-Prime, and their accuracy rate and reaction time were recorded in the study.Results ANOVA revealed that,in all cases,the accuracy rate of anger was significant higher than fear and sadness (96.60% ,94.50% ,94.40% ) (P<0.05).And when the flanking stimuli were fear faces or there were no flanking stimuli, the reaction time of anger was much shorter than fear and sadness ( respectively,fear(801.27 ± 140.99) ms,anger(723.94 ± 151.37 ) ms, sadness(812.21 ± 148.85 ) ms; fear(788.17 ±148.81 ) ms, anger ( 694.28 ± 111.99 ) ms, sadness (763.57 ± 133.91 ) ms, P < 0.05 ).When the flanking stimuli were anger or sadness faces, the reaction time of anger was significant shorter than fear( respectively, fear( 824.09 ± 164.42) ms, anger (721.48 ± 124.06 ) ms, sadness ( 760.50 ± 131.12 ) ms; fear ( 798.95 ± 146.40) ms, anger (702.55 ± 136.07 ) ms, sadness (750.48 ± 133.86) ms, P < 0.05).Conclusion There are no flanker effects in recognizing different negative emotional faces, but there are anger superiority effects of face recognition and cognitive tendencies, which is helpful for clinical diagnosis and treatment of some diseases associated with emotional disorders.
8.Roles of neurovascular unit in cognitive impairment induced by chronic cerebral hypoperfusion
Dapeng WANG ; Yifang WU ; Jian HAI
Chinese Journal of General Practitioners 2017;16(3):244-246
Chronic cerebral hypoperfusion (CCH) may result in neurovascular unit (NVU) injury,causing cognitive impairment.The NVU consists of neurons,glial cells,vascular cells and extracellular matrix.The damage of NVU can induce the blood-brain barrier dysfunction,abnormal cell signaling,as well as cognitive impairment.However,its molecular mechanism is unclear.Thus,investigating the role of NUV in CCH-induced cognitive impairment may provide a theoretical basis for the novel treatment of cognitive impairment.
9.Analysis on quality of leaves of improved Ginkgo biloba seedling sprout Ⅰ
Yifang YANG ; Hui WANG ; Yeying XIA ;
Chinese Traditional and Herbal Drugs 1994;0(11):-
Object To examine the quality of leaves from the improved Ginkgo biloba L seedling sprout Methods Total flavonoids in the leaves were determined by HPLC Results Flavonoids in the leaves of seedling sprout were apparently higher in June than in August and November, and were much higher than grafting seedling sprout which was also higher in June than in August 2 year old tree contained 2 5 to 3 8 times more flavonoids than 50 year old tree The content of female trees were higher than that of male Conclusion The content of active flavonoids were related to the season, age, breeding, environment and geographic conditions, etc
10.The application of systemic lupus erythematosus-specific quality of life questionnaire in systemic lupus erythematosus
Shuya WANG ; Wei TIAN ; Liang CHEN ; Zhiyi ZHANG ; Yifang MEI
Chinese Journal of Rheumatology 2014;18(3):190-194
Objective To elucidate the relationship between quality of life (QOL) and disease activity of systemic lupus erythematosus (SLE),as well as to reveal the factors impacting disease activity and the QOL of SLE utilizing the combination of SLE-specific quality of life questionnaire (SLEQOL) and the medical outcomes survey short form 36 (SF-36).Methods SLEQOL and SF-36 health survey questionnaire were applied.Information on gender,disease duration,age,education level were collected.Serum complement (C3 and C4) level and erythrocyte sedimentation rate (ESR) were measured.Patients were divided into inactive,mild active,moderate active and severe active respectively according to SLE disease activity index (SLEDAI).Pearson's product moment correlation coefficient was used to analyze the correlation between the activity of disease and the QOL.Multiple linear regression was employed to explore the factors which could impact on SLEQOL.Results The physical function of SLEQOL was positively correlated with SLEDAI (r=0.36; P<0.05).The association between reported health transition of SF-36 and SLEDAI was positive (r=0.19; P<0.05).Physical functioning,role-physical,role-emotional,body pain and vitality were all negatively correlated with SLEDAI (r:-0.20,-0.19,-0.19,-0.19,-0.21 respectively; P<0.05).The scores of patients with severe disease activity were significantly increased in the physical functioning of SLEQOL than other three groups (18±10 vs 11±5,12±6,13±7; P<0.05).Scores on the Health transition of patients with moderate and severe disease activity were lower than those of whom with mild disease activity (23±28.14±17 vs 34±39,P<0.05).Patients with mild or severe disease activity had lower score than those of patieuts in disease inactive (30±41,34±39 vs 44±44,P<0.05).Multiple linear regression analyses showed that disease duration and education level might be the influencing factors of SLEQOL.Conclusion QOL of patients with SLE is related to the level of disease activity and is impacted by disease duration and education.