1.Blood-Enriching Decoction of Angelica Sinensis Cause Improvements in Cellular Immunity
Chinese Journal of Immunology 1985;0(06):-
100 cases of patients with brain tumor were tested with lymphocyte transformation testand erythrocyte-rosette forming cell,the results showed the lymphocyte transfor-mation test and Erythrocyte-Rosette Forming Cell of the patients with brain tumorwas lower than that of the normal value,of the 100 postoperative brain tumor cases75 were treated with blood-enriching decoction of Angelica Sinensis and 25 were usedas control.The lymphocyte transformation test and erythrocyte-Rosette formingcell of the treated group showed a remarkable rise(P
2.A Sutdy on the Relationship among the Severity of Coronary Disease,CRP and Mild Renal Dysfunction
Li SHEN ; Yichen WANG ; Jun YIN
Journal of Chinese Physician 2001;0(09):-
Objective To explore the relationship among the severity of coronary disease, c-reaction protein (CRP) and mild renal dysfunction. Methods 64 patients underwent coronary angiography were divided into two groups according to their serum creatinine (cr) levels: normal renal function(cr
3.Deep neck abscesses accompanied by multiple underlying diseases: 2 case reports.
Yichen WAN ; Yan YAN ; Li WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2012;26(19):906-907
Patients who complained of pain, tenderness mass in neck, fever, limitation of mouth opening, pharyngalgia,dysphagia,with lab showing increased Neu, remarkably decreased PLT, upsurging Glu, urine-Glu, ALT, T-Bil, AFP, were finally diagnosed to suffer from deep neck abscesses after CT scanning. What was worth mentioning was that diabetes, hepatitis C, thrombocytopenia, and fungus infection added to the complexity of the treatment.
Abscess
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complications
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Adult
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Aged
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Blood Coagulation Disorders
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complications
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Diabetes Complications
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Hepatitis C
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complications
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Humans
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Male
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Mycoses
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complications
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Neck
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pathology
4.The proper orthogonal decomposition method for the Navier-Stokes equations
Axia WANG ; Yichen MA ; Wenjing YAN
Journal of Pharmaceutical Analysis 2008;20(3):141-148
The proper orthogonai decomposition (POD) method for the instatiouary Navier-Stokes equations is considered. Several numerical approaches to evaluating the POD eigenfunctions are presented. The POD eigenfunctions are applied as a basis for a Galerkin projection of the instationary Navier-Stokes equations. And a low-dimensional ordinary differential models for fluid flows governed by the instationary Navier-Stokes equations are constructed. The numerical examples show that the method is feasible and efficient for optimal control of fluids.
5.Spontaneous recovery of calculation and number processing in patients with stroke: a one-year follow-up study
Yichen YIN ; Suping ZHANG ; Wanqing DENG ; Muzhen WANG
International Journal of Cerebrovascular Diseases 2013;21(7):531-535
Objective To investigate the spontaneons recovery of calculation and number processing in patients with stroke.Methods Assessment of calculation and number processing were performed in 30 stroke patients with stable conditions (21 cerebral infarction and 9 cerebral hemorrhage) within 3 weeks after stroke,and they were followed up for one year.Calculation and number processing was assessed using the Revised EC301 Calculation and Number Processing Battery in Chinese version at 3,6,and 12 months after stroke onset.Results The scores in the areas of numerical sequences,numerical understanding,numerical transcoding,numerical calculation,numerical knowledge and the total scores increased significantly with the passage of time (all P <0.001).There were significant differences between each area and total scores at 3,6,and 12 months after stroke and those at 3 weeks (all P <0.01),however,there were no significant differences among the three time points.The total scores and the scores in each area increased significantly with the passage of time in the cerebral infarction group and the hemorrhage group (all P <0.001),however,there were no significant differences in each area at the same time point between the two groups.There was significant difference in the recovery of the total scores between the cerebral hemorrhage group and the cerebral infarction group (P =0.008).Pearson correlation analysis showed that the recovery of the calculation and number processing in all patients (R =0.452,P =0.012) as well as in the cerebral infarction group (R =0.683,P=0.001) and the cerebral hemorrhage group (R =0.250,P =0.049) within one year showed a significant positive correlation with the total score of the first assessment.Conclusions The impaired calculation and number processing may partly spontaneously recover after stoke,and it shows significant improvement within 3 months after onset.The recovery in patients with cerebral hemorrhage may be better than that in those with cerebral infarction.The more serious the impairment in initial calculation and number processing,the worse the spontaneous recovery will be.
6.Observation on the effect of different types of statins combined with donepezil in the treatment of Alzheimer disease
Yichen YIN ; Wuhua XU ; Muzhen WANG ; Suping ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2013;20(18):2721-2723
Objective To explore the effect of different types of statins combined with donepezil in the treatment of Alzheimer disease(AD).Methods According to the digital table,90 patients with AD were randomly divided into the statins A group(atrovstatin combined with donepezil) 31 cases,statins B group(simvastatin combined with donepezil)27 cases,and donepezil group(only with donepezil) 32 cases.All patients were treated for one year.The blood lipid level (including cholesterol (CH) and low density lipoprotein cholesterol (LDL-C),mini-mental state examination(MMSE),activity of daily living(ADL) and global deterioration scale (GDS) were detected and compared respectively among groups before and after treatment.Results The MMSE,ADL and GDS scores of the donepezil group were (17.00 ± 2.99) points,(60.44 ± 14.57) points,(4.28 ± 1.22) points,respectively,which were worse than those of the statins A group [(19.90 ± 3.07) points,(71.61 ± 18.50) points,(3.39 ± 1.15) points] (t =0.218,P < 0.05,t =2.669,P < 0.01,t =2.562,P < 0.01) and statins B group [(19.88 ± 6.66) points,(71.89 ± 19.61) points,(3.37 ±l.39)points](t=l.959,P <0.05,t=2.991,P <0.0l,t=2,265,P <0.01).Conclusion The combination of donepezil and statins can effectively improve cognitive function and daily living ability in patients with AD,and its effect is superior to single use of donepezil.
7.Hormone replacement therapy for gynaecological cancer
Yichen WANG ; Xiaoxian XU ; Yanmin SHEN ; Aijun YU
Journal of International Oncology 2012;39(10):778-781
Treatment of gynaeeological cancer frequently results in the loss of ovarian function and menopausal syndrome.The most effective treatment is hormone replacement therapy (HRT).According to the current studies,HRT does not increase the risk of recurrence or death in patients with early stage endometrial cancer and uterine leiomyosarcomas. The safety of HRT in ovarian cancer patients is inconclusive. Cervical squamous cell carcinoma, vaginal cancer and vulvar cancer are not contraindications for HRT. Estrogen replacement therapy (ERT) is contraindicated for low-grade endometrial stromal sarcomas. Therefore,after integrated risk assessment and discussion,patients with severe menopausal symptoms can be treated with HRT to improve the quality of life.
8.Factors affecting the treatment of hypertension in Elderly in the community of Yanji Area of Shanghai
Yichen WANG ; Jinglong ZHANG ; Qian CHEN ; Hanji SHANG ; Yanling XU
Chinese Journal of Hypertension 2001;9(2):167-168
Objective To evaluate the factors affecting the treatment of old persons diagnosed hypertension. Method A sample of 55566 persons from the community of Yanji area of Shanghai was recruited. Results Among the 19295 persons over sixty there are 5842 patients with hypertension, the morbidity was 30.3%. Among the 36271 persons aged fifteen to fifty-nine there are 3536 patients with hypertension, the morbidity is 9.7%. The ratio of non-treatment in the old age group is 3.1% and in younger group is 8.8%. However,the compliance to the treatment was better in the younger than in old group(73.7% vs 56.2%). The age,hypertension grade and sex were all accounted for the differences in the regularity of the hypertension treatment. Conclusion Further effort on the education of non-old hypertensive patients is essential to decrease the damage from hypertension.
9.Clinical study of the relationship between the level of morning blood pressure surge and hs-CRP in coronary events among old patients
Weisheng LU ; Shuyan CHEN ; Jiangrong ZHANG ; Zhihong PAN ; Yichen WANG
Journal of Chinese Physician 2011;(z1):13-16
Objective To explore the relationship between the level of morning blood pressure surge (MBPS) and High-sensitivity C-reactive protein( hs-CRP) in acute coronary events among old patients and to evaluate their clinical value. Methods One hundred and twenty - three patients with coronary disease were divided into two groups, each of which was old myocardial infarction(OMI, n = 55) and old myocardial infarction with acute cardiovascular syndrome (OMI + ACS, n =68). The control group includes the patients without coronary disease( n =50). The patients who have infection, malignant tumors, liver and kidney dysfunction, blood diseases, valvular heart diseases, congenital heart diseases, aortic dissection,secondary hypertension were not included. All groups were received 24 hours ambulatory blood pressure monitoring to calculate MBPS and the determination of hs-CRP in serum. Results Compared with each two groups, the levels of MBPS and hs-CRP in OMI group were significantly higher than those of the control group (0. 01 < P <0. 05) , and had more significance in the other groups ( P <0.01). The levels of MBPS and hs-CRP had positive relationship in coronary events in the elderly ( r =0. 76, P <0. 01) . Conclusion The level of MBPS is positively correlated with serum hs-CRP which is one of key risk factors of inflammatory reactions by impairing vessels in body. The two factors both play important roles in the occurrence and the development of coronary events among old patients. They both have important clinical value in recurrent acute coronary events among old patients.
10.Impact of hyperglycemia on hypersensitive C-reaction protein, B-type natriuretic peptide and ventricular remodeling of elder patients with acute myocardial infarction
Weisheng LU ; Fang LIU ; Jiangrong ZHANG ; Huimin YUAN ; Yichen WANG
Clinical Medicine of China 2014;30(11):1156-1158
Objective To explore the impact of hyperglycemia on Hypersensitive C-reaction protein (hsCRP),B-type natriuretic peptide(BNP) and ventricular remodeling in elder patients with acute myocardial infarction(AMI).Methods One hundred and twenty elder patients with AMI are divided into hyperglycemia group(blood sugar in admission > 7.8 mmol/L) and non-glycemia group(blood sugar in admission ≤7.8 mmol/L).The levels of blood sugar in admission,hsCRP,BNP were detected.LVEF,LVEDD,LVESD,WMS were observed by cardiac echo in admission and two weeks after therapy.Results The blood sugar in admission,hsCRP and BNP of the patients in hyperglycemia group were (9.6 ± 0.6) mmol/L,(1 750.6 ±677.1) ng/L,(56.1 ±38.6) ng/L,higher than those in non-glycemia group (t =38.679 and P =0.000; t =11.941 and P =0.000; t =3.288 and P <0.01,respectively).LVEF,LVEDD,LVESD and WMS of patients in hyperglycemia group didn't show statistical significance before and after therapy.However,there were significant in hyperglycemia group (t =2.049 and P =0.043,t =2.836 and P =0.005,t =3.814 and P =0.000,t =2.086 and P =0.039,respectively).Conclusion Hyperglycemia can reduce the increase of hsCRP and BNP,which has an impact on hsCRP,BNP and ventricular remodeling in elder patients with acute myocardial infarction,but the mechanism need to further research.