1.Application of ultrasound for simulated positioning of brachytherapy in cervical cancer: An alternative to traditional MRI/CT?
Yicen ZOU ; Ning ZHANG ; Guanghui CHENG ; Dongmei HAN
Chinese Journal of Radiation Oncology 2018;27(7):701-705
The role of three-dimensional brachytherapy (3D-BT) in the radical treatment of cervical cancer has been widely recognized. Obtaining the image information through simulated positioning is a key step of 3D-BT.Currently, MRI/CT positioning has been commonly applied in clinical practice, which has respective limitations when applied in radiosurgery. Consequently, it is of necessity to explore an accurate, highly efficient and convenient positioning approach. Besides MRI and CT, ultrasound is a novel positioning method in clinical settings. Through literature review, the application of ultrasound in 3D-BT was summarized, aiming to provide reliable reference for clinicians.
2.Survival analysis on patients with occupational pneumoconiosis in Guangdong Province from 1980 to 2019
Xi WU ; Fanli MENG ; Ru JING ; Yuhao HAN ; Yuhao WANG ; Yicen GU ; Daoyu YANG ; Ningbin QUAN ; Jinbi PENG ; Xudong LI
China Occupational Medicine 2023;50(2):140-144
3.The predictive effect of ARIMA model for occupational pneumoconiosis in Guangdong Province
Yuhao HAN ; Xi WU ; Jinbi PENG ; Yuhao WANG ; Ru JING ; Daoyu YANG ; Yicen GU ; Ningbin QUAN ; Xudong LI
China Occupational Medicine 2023;50(2):150-154
4.A study on the impact of long working hours on the psychological health of medical personnel in third class hospitals
Ningbin QUAN ; Jin WANG ; Yuhao WANG ; Ru JIN ; Daoyu YANG ; Jinbi PENG ; Yicen GU ; Yuhao HAN ; Jingyi LU ; Zhao ZHANG ; Luyao XU ; Shuling HUANG ; Xiaozhou SU ; Xudong LI
The Journal of Practical Medicine 2023;39(24):3267-3274
Objective To understand the characteristics of long-working hours exposure of medical staff,and analyze the impact of long-working hours exposure on mental health problems such as occupational stress,depression,fatigue accumulation,and insomnia.Methods The cluster random sampling method was used to select the medical staff of 12 tertiary general hospitals in Guangdong Province as the research subjects,and the"Core Scale of Occupational Stress Measurement"and other scales were used to evaluate their occupational mental health.Results The average working hours of medical staff per day were(8.99±2.18)h;2,094 people were exposed during long working hours,accounting for 78.96%.The results of binary logistics regression analysis showed that after excluding the influence of sociodemographic factors such as age,long working hours(weekly working hours greater than 40 h)were the risk factors for occupational stress,depressive symptoms and fatigue accumulation of medical staff(P<0.01),and the longer the working week,the higher the risk of occupational stress,depressive symptoms and fatigue accumulation.Weekly working hours greater than 48 hours are risk factors for insomnia(P<0.01).Conclusion Long working hours are common among delivery workers on food delivery platforms,and long working hours are a risk factor for occupational tension and fatigue.
5. Effects of different administration methods on the pharmacokinetics and tissue distribution of ribavirin in rats
Lu GUO ; Yicen HAN ; Xiaoshu LIU ; Jing ZHANG ; Qin LANG ; Tian ZHONG ; Zhendong ZHONG ; Yi SHI ; Yong YANG ; Yuan BIAN
Chinese Journal of Clinical Pharmacology and Therapeutics 2022;27(1):25-32
AIM: To establish a HPLC-QqQ-MS with multiple reaction monitoring (MRM) method for pharmacokinetics and tissue distribution study of ribavirin by oral and respiratory administration. METHODS: The experiment established a high-sensitivity LC-MS analytical method for the detection of ribavirin, and the linearity, specificity, recovery, accuracy, and precision were investigated. The established methods were used to investigate the pharmacokinetics and tissue distribution of the oral and respiratory administration methods. RESULTS: The concentration of drugs in the blood through respiratory tract administration is higher, and the drug absorption is faster. Respiratory tract administration C