1.Materials for cartilage repair following sport articular cartilage injury
Chinese Journal of Tissue Engineering Research 2007;0(12):-
Knee joint is easily injured in daily life, in particular, incidence rate of articular cartilage is high due to a long-term high pressure stress and poor regeneration capacity. Therefore, articular cartilage injury is hard to be treated and attracts more and more attention in the domain of sport medicine. At present, a large quantity of methods for repairing cartilage is still developing. The recent studies indicate that autoallergic cartilage transplantation is the best method to repair sport articular cartilage injury. However, it is hard to be used widely due to its poor collection. In contrast, cell transplantation is frequently used to repair articular cartilage injury, but scaffold materials involving in long-term instability still need to be further studied in the future.
2.The usage of continuous suction through catheter in the surgery of endoscopic correction of nasal septum without nasal packing
Shouhou LIU ; Chen TANG ; Yibing WANG
Chinese Journal of Primary Medicine and Pharmacy 2011;18(4):497-499
ObjectiveTo explore the feasibility of non-nasal packing after correction of nasal septum. Methods53 cases of simple deviation of nasal septum were underwent endoscopic correction of nasal septum.The continuous suction in surgical cavity through catheter without nasal packing after surgery was applied to 46 cases with intact double-mucosa or little wound that could be sutured in front of nasal septum. ResultsOf the 46 patients,the volume of the bleeding 3 days after the operation were(8.1 ± 5.6)ml.The degree of the nasal mucosa edema in 33 patients were lightened than others,the space between the inferior nasal concha and the nasal septum were fine as well as the ventilation of the nasal cavity.Among those cases,there were 13 patients with severe nasal mucosa edema(5 cases were allergic rhinitis)which were treated with ephedrine and furaciline solution or glucocorticoid,as the results,the nasal mucosa shrinked,and the patients could respire well.The catheter were extracted 3 days after the operation until the primary healing.All the cases were healing well without the the nasal septum hematoma and other complications which were follow up more than half a year. ConclusionThe method of continuous suction in surgical cavity through catheter without nasal packing was feasible if double nasal septum mucosa was intact after correction of nasal septum.
3.Application of computer to medical ultrasound images
Yibing LI ; Dakun YU ; Xiaodong LIU
Chinese Medical Equipment Journal 1989;0(04):-
This paper introduces the application of computer to medical ultrasound images in which the processing of medical ultrasound images and picture archiving and communication system(PACS) are involved in.
4.Model Curricula Development of Clinical Biochemistry
Yibing YIN ; Beizhong LIU ; Zhiguang TU
Chinese Journal of Medical Education Research 2006;0(08):-
As required to the standards of the model curricula and with the years of continuous teaching research and reforming,the clinical biochemistry curriculum has kept developing from the teaching staff,content of course,teaching method and means and the teaching condition etc.,thus forming model curricula with special features and notable results.
5.Treatment of Acute Mesenteric Venous Thrombosis:12 Cases Report
Wenguo LIU ; Yibing WENG ; Yu WANG
Chinese Journal of Rehabilitation Theory and Practice 2008;14(6):578-579
Objective To detect the effect of the operative and non-operative therapy on acute mesenteric venous thrombosis (AMVT).Methods The documents of 18 AMVT patients from Jan 1990 to May 2006 were reviewed retrospectively.Results In 18 patients, 12 cases with intestinal necrosis received operation, among them, 2 cases received the operation only and 10 cases added with anti-coagulation therapy further. The rest 6 patients received non-operative therapy. All of 18 patients recovered well.Conclusion Non-operative therapy is safe and effective for the patients without intestinal necrosis. Post-operative anti-coagulation therapy is very important for the patients received the operative therapy.
6.Pseudomonas aeruginosa injection inhibits proliferation of human carcinoma cell lines
Yibing LIU ; Dali HU ; Yumeng ZHOU ; Qiling HUANG ; Shiyun PAN
Chinese Journal of Clinical Oncology 2013;(12):694-697
10.3969/j.issn.1000-8179.2013.12.003
7.Inducing scientific thinking and practice in the proteomics course for postgraduates
Manran LIU ; Lan ZHOU ; Xuemei ZHANG ; Yurong YAN ; Yibing YIN
Chinese Journal of Medical Education Research 2013;(7):677-679
Teachers introduced the means of the scientific thinking and scientific research prac-tice in the curriculum of proteomics in order to train the postgraduates to joint the theory and the practical research work in the curriculum course. For example, to cultivate students to truly understand the 2-DE protein separation technique, teachers used the various proteomic profile obtained from our research to points out its problems and limitations based on the classical 2-DE, then compared the improved 2-DE protein separation chromatography with the classical 2-DE graphic and analyzed what is the problem and how to solve them in the practical work. To improve the ability of scientific thinking for postgraduates , teachers took the tumor as the teaching cases and asked the postgraduates to search the references of can-cer associated with their professional , to put forward the scientific problems based on carefully reading these references, to design their research project and to seek the answer to their issue. These new teaching methods were found to be beneficial in training scientific talents of medical postgraduates.
8.Effect of Radix astragali on the expression of myocardial Cx43 in rats with dilated cardiomyopathy
Yonghua YUAN ; Xuehua HE ; Yibing FANG ; Liping LIU ; Xiaohui XIA
Journal of Clinical Pediatrics 2014;(11):1080-1083
Objective To observe the effect of Radix astragali (RA) on myocardial connexin-43 in rats with dilated cardiomyopathy (DCM). Methods The dilated cardiomyopathy model in rat was established through intraperitoneal injection with adriamycin. The rats in the model group were randomly divided into RA group and the model control group according to different methods of administration. Rats in RA group were gavaged with Astragalus particles and double-distilled water, and rats in model control group and normal control group were gavaged with an equal amount of double-distilled water daily for four weeks. At the end of 12 weeks, the left ventricular ejection fraction (LVEF) was measured with echocardiogram. The Cx43 mRNA level was tested by reverse transcriptase polymerase chain reaction (RT-PCR). Immunohistochemical method was used to observe myocardial Cx43 expression and distribution. Results Compared with the model control group, the Cx43 mRNA and protein expressions and LVEF were increased signiifcantly in RA group (P<0.05). The disorders in distribution of myocardial Cx43 improved in RA group in contrast to the model control group. Conclusions Radix astragali can improve myocardial Cx43 expression and distribution in DCM rats, and can further improve the cardiac function.
9.Pull-through Welch procedure for the lower rectal carcinoma: a report of 28 cases
Daorong WANG ; Yibing ZHOU ; Guoyu CHEN ; Xunliang LIU ; Jusheng XU ;
Chinese Journal of General Surgery 1993;0(01):-
Objective To find a novel operative modality with sphincter preservation in the treatment of middle and low rectal carcinoma. Methods Pull through lower resection was performed on 28 rectal cancer patients. The distance between the anal verge and the lower margin of the tumor was 6~8cm(20 patients) or 8~10cm(8 patients), including 8 patients in Dukes A stage, 16 Dukes B and 4 Dukes C. The resected line from tumor distal margin was 2cm, 3cm, and 4cm, respectively. Results There was no operative death, anastomotic fistula or anastomotic stenosis in these cases. Mean follow up period was 30 months. Local recurrence was found in two cases (7.1%) 18 months after the operation, and 26 cases were cancer free till the end of the follow up. Defecation was satisfactorily controlled 8~12 weeks after the operation. Conclusions Pull through Welch procedure could meet the criterion of the radical resection of rectal carcinoma,and keep the internal and external sphincter muscles intact in the superior lower anterior resection. The normal defecationcan can maintain after the operation due to the preservation of internal and external sphincter muscles.
10.Optimized design of mini-implant diameter and length in IV osteoid through three- dimensional finite element analysis
Guanjun ZHOU ; Chenxi LI ; Xiaoli JIAO ; Yibing LIU ; Lihua SHAN
Chinese Journal of Tissue Engineering Research 2016;20(12):1812-1817
BACKGROUND:Diameter and length of mini-implant have effects on its stability, which has been reported mostly in I and II osteoid, but less in IV osteoid. OBJECTIVE:To optimize the design of mini-implant diameter and length in IV osteoid by a three-dimensional finite element analysis. METHODS:Implant-mandible solid model was established. A 2 N orthodontic force that was perpendicular to the long axis of the implant and at a 30° angle with the distal central axis was applied onto the top of the implant. The implant was designed for different diameters (1.2-2.0 mm) and lengths (6-10 mm). Peak stress and peak displacement of the mandible were mechanicaly assessed, and stress sensitivity variables were analyzed. RESULTS AND CONCLUSION:The stress and displacement of the implant were mainly concentrated in the neck of the implant. The stress of implant-bone interface mainly focused on the contact area of the implant-cortical bone interface, and the stress of the cancelous bone was relatively smal, but the stress of the cortical bone was weakened faster. When the implant length was constant, the implant diameter had a great effect on stress changes, and the stress of bone tissue was reduced with the increase of implant diameter. When the implant diameter was constant, the implant length had no significant effect on the stress of bone tissue. To sum up, the stress of bone tissue and displacement were sensitive to the change of implant diameter rather than the change of implant length. These findings indicate that implant diameter has a greater effect on stress distribution of bone tissue than the implant length, and the implants with > 1.5 mm in diameter are suitable for IV osteoid.