1.Advances in studies on cerebral creatine deficiency syndrome.
Chinese Journal of Pediatrics 2010;48(6):445-448
Brain
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metabolism
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Brain Chemistry
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Creatine
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deficiency
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Humans
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Syndrome
2.Effect of understanding of stroke patients for illness on direction of rehabilitation
Chinese Journal of Rehabilitation Theory and Practice 2004;10(12):749-750
ObjectiveTo investigate the understanding of stroke among stroke patients and promote the direction of rehabilitation.MethodsA survey was carried out among 80 stroke patients by questionnaire.Results42.5% of those patients knew nothing about the risk factor of stroke and the rate of right behavior related to maintain health was relatively low. The rate of satisfaction with rehabilitative direction was only 66.3% though 98% patients had experienced that direction.ConclusionIntensive and continuous direction of rehabilitation is necessary for the stroke patients. Comprehensive health education should be given to those patients to ensure their best self care and improve their quality of living.
4.MRI Manifestation of Temporomandibular Joint after Trauma
Hua WANG ; Xiaoying WANG ; Yi ZHANG ; Dongmei HE ; Xuexiang JIANG
Journal of Practical Radiology 1991;0(03):-
Objective To investigate MRI manifestations of temporomandibular joint trauma,emphasized on the displacement and deformation of the meniscus.Methods Thirteen patients with TMJ trauma were examined by MRI with 3-inch dual surface coils.T1WI and T2WI images in oblique sagittal and coronal plane were acquired in both closed-and open-mouth positions.Results Twenty(20/26,76.9%) joints had condylar fractures.Nineteen(19/20,95%) discs in 12 patients displaced anteromedially with the condylar fragments,six(6/20,30%) discs showed distortion and deformation.The other one patient had unilateral condylar fracture companied with avulsion and lateral dislocation of ipsilateral disc(1/20,5%),and the opposite disc also showed slight anterior displacement.Effusion was observed in 12(12/20,60%) joints with condylar fractures.The location of the discs didn't show obvious change between closed-and open-mouth positions.Conclusion MRI is an effective method for demonstrating TMJ injuries,and is useful for detecting the changes of morphology and position of the discs.
5.Content Determination of Cabozantinib in Its Raw Material by RP-HPLC
Wei XU ; Changjuan ZHAN ; Hua WANG ; Yi WANG ; Qi GUO
China Pharmacy 2017;28(12):1696-1698
OBJECTIVE:To establish a method for the content determination of cabozantinib in its raw material. METHODS:RP-HPLC method was adopted. The determination was performed on Inertsil ODS-SP C18 column with mobile phase consisted of acetonitrile-0.02 mol/L ammonium acetate buffer (pH 5.2,52:48,V/V) at the flow rate of 1.0 mL/min. Detection wavelength was set at 241 nm,the column temperature was 38 ℃,and sample size was 20 μL. RESULTS:The linear range of cabozantinib were 9.88-49.40 μg/mL(r=0.9999). The limit of quantitation was 11.46 ng,and the limit of detection was 3.36 ng. The RSDs of preci-sion,stability,repeatability tests were all lower than 2.0%;recoveries were 98.5%-101.7%(RSD=1.2%,n=9). CONCLU-SIONS:The method is simple,accurate and suitable for the content determination of cabozantinib in its raw material.
6.Drug Release Comparison of Nifedipine Sustained-release Tablets from Four Manufacturers
Yi WANG ; Changjuan ZHAN ; Wei XU ; Hua WANG ; Yong ZHANG
China Pharmacist 2014;(11):1856-1858
Objective:To compare the drug release of nifedipine sustained-release tablets from four manufacturers to evaluate the intrinsic quality. Methods:The drug release rate was determined by UV respectively with pH 1. 2 HCl solution, pH 4. 0 sodium ace-tate buffer, pH 6. 8 phosphate buffer and water as the dissolution medium. The dissolution curves were compared by f2 factor. Results:The drug release rate of nifedipine sustained-release tablets from the four manufacturers all met quality standard of our country, al-though the dissolution curves in the different dissolution medium was various. Conclusion:There are differences in intrinsic quality a-mong the nifedipine sustained-release tablets from the four manufacturers. The dissolution examination standard should be improved fur-ther.
7.Effects of Hyperbaric Oxygen Combined with Fastigial Nucleus Stimulation on Chronic Cerebral Circulation Insufficiency with Transcranial Doppler and Electroencephalography
Lei WANG ; Yi HE ; Hu ZHENG ; Hua WANG ; Houcheng LI
Chinese Journal of Rehabilitation Theory and Practice 2009;15(12):1130-1132
Objective To observe the of changes of cerebral blood flow and electroencephalography in chronic cerebral circulation insufficiency (CCCI) treated with fastigial nucleus stimulation (FNS) and hyperbaric oxygen (HBO). Methods 144 cases of CCCI were divided into 4 groups: 36 cases were treated with FNS and HBO, 36 cases with FNS, 36 cases with HBO, 36 cases without any treatment as control group. The blood velocity of anterior, middle, posterior cerebral arteries, vertebral artery and basilar artery were measured with transcranial Doppler (TCD) and the brain waves (α, β, δ, θ) were recorded with electroencephalography (EEG) before and after the treatment. Results Compared with the control, the brain blood velocity and α wave increased in all the treatment groups, especially in the HBO+FNS group, while β, δ, θ waves decreased (P<0.05). Conclusion FNS and HBO can increase cerebral blood flow and improve the cerebral function respectively.
9.Airway management in acute cyanide poisoning.
Min-xiao LIU ; Guo-hua ZHOU ; Yi-hong WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2010;28(2):152-153
Adult
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Aged
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Airway Management
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Cyanides
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poisoning
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Female
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Humans
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Male
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Middle Aged
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Poisoning
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nursing
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Young Adult
10.Relationship between Renal Nitric Oxide and Glomerular Hyper filtration in Experimental Diabetic Rats
ming-hua, LIU ; shu-zhen, SUN ; qian, LI ; yi, WANG
Journal of Applied Clinical Pediatrics 1986;0(01):-
Objective To explore the mobile changes of nitric oxide(NO) and the relationship between nitric oxide and glomerular hyperfiltration in experimental diabetic rats.Methods Experimental diabetes mellitus(DM) was induced in rats with streptozotocin(STZ).The levels of NO and NOS in renal tissue homogenate were assayed after establishment of diabetesat the 4 th,8 th,12 th week.At the same time, renal morphology in diabetic rats was examined by light microscope and image of computer.Results The contents of NO and NOS in renal homegenates were evidently increased at 4 th week,and decreased gradually from 8 th week(P